| Digitava Ltd | Information & communication | 2019 |
| Digitech Data Ltd | Information & communication | 2021 |
| Digitelenetworks Ltd | Information & communication | 2021 |
| Digitrack Analytics Limited | Extraterritorial | 2020 |
| Diir Consulting Limited | Professional & scientific | 2010 |
| Dilieto Cafe Limited | Hospitality | 2022 |
| Dilini Property Management Ltd | Real estate | 2023 |
| Dilli Vibes Ltd | Manufacturing | 2025 |
| Dima and Sons Property Ltd | Real estate | 2022 |
| Dimension Property Service Ltd | Construction | 2024 |
| Dining Orpington Limited | Hospitality | 2025 |
| Diop Services Limited | Professional & scientific | 2026 |
| DIR Services Limited | Transport & logistics | 2016 |
| Dirdan Limited | Professional & scientific | 2026 |
| Direct Response Building Maintenance Ltd | Construction | 2012 |
| Direct Stars Ltd | Education | 2023 |
| Direct Workplace Solutions Ltd | Construction | 2019 |
| Dirty Dozen Ltd | Administrative & support | 2023 |
| Discover London Tours Ltd | Administrative & support | 2010 |
| Disrupteve Property Limited | Real estate | 2022 |
| Disruptive Engineering Limited | Information & communication | 2019 |
| Distribution Resourcing Services Ltd | Transport & logistics | 2016 |
| District Services (Southern) Ltd | Construction | 2015 |
| Divas & Dudes Hair Boutique Ltd | Other services | 2013 |
| Divine Additions Limited | Real estate | 2001 |
| Divine Skill Limited | Other services | 2019 |
| Divluna Ltd | Health & social care | 2016 |
| DJ Stream TV Ltd | Arts & recreation | 2023 |
| DJB Legal Services Ltd | Professional & scientific | 2021 |
| DJD Events Limited | Manufacturing | 2024 |
| DJM Elevators Limited | Professional & scientific | 2012 |
| Djshn Investments Limited | Real estate | 2024 |
| DK888 Limited | Construction | 2024 |
| DL Investments Holding Limited | Financial services | 2023 |
| DM Lifters Ltd | Transport & logistics | 2024 |
| Dm-Ai Limited | Professional & scientific | 2025 |
| Dmao Services Ltd | Other services | 2023 |
| DMC Construction Ltd | Construction | 2026 |
| DMC FIN Consulting Ltd | Professional & scientific | 2023 |
| DMG Keys Limited | Hospitality | 2024 |
| Dmitri Martin Associates Limited | Professional & scientific | 2016 |
| Dmitro Development Ltd | Construction | 2018 |
| DMS Locum Ltd | Health & social care | 2013 |
| DNS Solutions Ltd | Extraterritorial | 2018 |
| DO & EL Limited | Hospitality | 2013 |
| DO Cycling Limited | Wholesale & retail | 2020 |
| DO More Daily Ltd | Wholesale & retail | 2018 |
| Doback Ventures Limited | Financial services | 2024 |
| Dobcom Limited | Information & communication | 2014 |
| Dockside Marine Detailers Ltd | Wholesale & retail | 2025 |
| Doesitwell Ltd | Administrative & support | 2017 |
| Dolce Restaurant Chain Services Limited | Hospitality | 2023 |
| Dolomite Renovations Limited | Construction | 2016 |
| Domelia Dental Ltd | Health & social care | 2020 |
| Domestic Ltd | Manufacturing | 2018 |
| Dominics Transport Limited | Construction | 2024 |
| Donald Macintosh Property Services Limited | Real estate | 1958 |
| Donegan Electrical Limited | Construction | 2014 |
| Donev Group Ltd | Construction | 2015 |
| Donmor Global Services Limited | Transport & logistics | 2018 |
| Donovan Bros. Limited | Wholesale & retail | 1947 |
| Donrynure Limited | Households | 1982 |
| Dontay Solutions Ltd | Wholesale & retail | 2024 |
| Dony Andreica Ltd | Construction | 2025 |
| Dora Design & Art Limited | Information & communication | 2019 |
| Dorchester Green Apartments Limited | Construction | 2024 |
| Dormer Properties Limited | Construction | 2020 |
| Dorrington Court Property Management Limited | Households | 1991 |
| Dorryn Limited | Households | 1997 |
| Dorset Holidays Ltd. | Extraterritorial | 2023 |
| Dosa Adda Ltd | Hospitality | 2024 |
| Dott-It Limited | Information & communication | 1998 |
| DOUBLELUCK88 Limited | Hospitality | 2024 |
| Dove Corporate Services (UK) Ltd | Other services | 2025 |
| Dover Development Inc. | | 1992 |
| Down to Earth Garden Services Limited | Administrative & support | 2023 |
| Downe Livery Ltd | Agriculture & fishing | 2020 |
| Downriver Limited | Manufacturing | 2022 |
| DP BIN Cleaning Ltd | Administrative & support | 2025 |
| DR Jarek Nowacki Locum Practice Limited | Health & social care | 2014 |
| DR Mani Vision Care Limited | Health & social care | 2012 |
| DR Mayur Kumar Limited | Health & social care | 2014 |
| DR Melanin Ltd | Health & social care | 2023 |
| DR Nuri Dent Ltd | Health & social care | 2022 |
| DR Remigiusz Lecybyl Ltd | Professional & scientific | 2011 |
| DR Software Solutions Limited | Information & communication | 2014 |
| DR Zeena Skin & Wellness Clinic Ltd | Other services | 2019 |
| DR. Parnerkar Poornawad Foundation | Health & social care | 2024 |
| Dr.Hope Limited | Health & social care | 2013 |
| Draft Projects Ltd | Construction | 2024 |
| Dream Carpentry Ltd | Manufacturing | 2021 |
| Dream Design Build Ltd | Professional & scientific | 2025 |
| Dream House Project Ltd | Construction | 2020 |
| Dream Pursuit Media Ltd | Professional & scientific | 2020 |
| Dreamhouse Builders Ltd | Construction | 2023 |
| DRG Direct Building Ltd | Construction | 2016 |
| DRG Limited | Professional & scientific | 2015 |
| DRH Group Limited | Financial services | 2024 |
| Driffield Support Ltd | Information & communication | 2019 |
| Drilon Development Ltd | Construction | 2016 |