| OIL Recoveries Limited | Water & waste | 2010 |
| OIL Resources Limited | Wholesale & retail | 1997 |
| Oitas Services Limited | Construction | 2004 |
| OJ Mcauley Ltd | Manufacturing | 2025 |
| Olcotwish C.I.C. | Hospitality | 2018 |
| Olive Door Limited | Real estate | 2014 |
| Oliver C Stevens Financial Planning Ltd | Professional & scientific | 2026 |
| Olivia Grange Management Company Limited | Real estate | 2003 |
| Ology Kids Casting Limited | Administrative & support | 2018 |
| OLU Ltd | Energy | 2024 |
| Olumo Rock Properties Ltd | Construction | 2024 |
| Olyvine Ltd | Other services | 2021 |
| OM Kitchens Ltd | Wholesale & retail | 2025 |
| Omnia Consultancy Services Limited | Wholesale & retail | 2022 |
| Omskrik Discount Ltd | Wholesale & retail | 2024 |
| ON the Grind Coffee Ltd | Hospitality | 2023 |
| One Vision Services Limited | Administrative & support | 2024 |
| Online Chemistry Tutor Ltd | Education | 2016 |
| Online Home Services Limited | Information & communication | 2024 |
| Online Supplement Ltd | Wholesale & retail | 2024 |
| Ooosh! Your Local Driving School Ltd | Education | 2019 |
| Operators Philosophy Syndicate Ltd | Other services | 2020 |
| Opollo Salon Suites (Whitchurch) Limited | Real estate | 2024 |
| Optiglaze Systems Ltd | Construction | 2025 |
| Orange Track Ltd | Information & communication | 2012 |
| Orbita Black Limited | Administrative & support | 2014 |
| Orchard Lodge (Residents) Limited | Households | 1993 |
| Orchard Point Limited | Administrative & support | 2016 |
| Orcol Limited | Water & waste | 2024 |
| Organic DAN Limited | Agriculture & fishing | 2003 |
| Ormskirk Accounting Ltd | Professional & scientific | 2023 |
| Ormskirk Boxing Academy Community Interest Company | Arts & recreation | 2024 |
| Ormskirk Chippy Ltd | Hospitality | 2021 |
| Ormskirk Civic Hall CIC | Arts & recreation | 2016 |
| Ormskirk Garage Ltd | Wholesale & retail | 2023 |
| Ormskirk Golf Club Limited | Arts & recreation | 2022 |
| Ormskirk Healthcare Limited | Wholesale & retail | 2010 |
| Ormskirk Heritage Hub CIC | Education | 2025 |
| Ormskirk Instruments Limited | Real estate | 1993 |
| Ormskirk Lettings Limited | Real estate | 2008 |
| Ormskirk Market Ltd | Wholesale & retail | 2021 |
| Ormskirk Martial Arts Limited | Other services | 2017 |
| Ormskirk Masonic Hall Company Limited(The) | Hospitality | 1965 |
| Ormskirk Mini-Mart Ltd | Wholesale & retail | 2020 |
| Ormskirk Mortgages Limited | Financial services | 2002 |
| Ormskirk Pizza LA Kebab Ltd | Hospitality | 2016 |
| Ormskirk Properties Limited | Real estate | 2016 |
| Ormskirk Rufc Trading Limited | Hospitality | 2024 |
| Ormskirk Skip Recycling Limited | Water & waste | 2011 |
| Ormskirk Student Lettings Limited | Real estate | 2013 |
| Ormskirk Windows Ltd | Construction | 2026 |
| Oscar Delta Ltd | Financial services | 2016 |
| Oscarsports Ltd | Arts & recreation | 2025 |
| Osei Ltd | Professional & scientific | 2019 |
| OT Catton Ltd | Construction | 2018 |
| Oteca Ltd | Professional & scientific | 2023 |
| Othala Builders Ltd | Construction | 2025 |
| OTR Communications Ltd | Information & communication | 2022 |
| Outer Reach Ltd | Professional & scientific | 2024 |
| Overbury Solutions Limited | Manufacturing | 2014 |
| OYM Sports Ltd | Manufacturing | 2026 |
| P & a Projects Limited | Manufacturing | 2003 |
| P & C Communications Limited | Information & communication | 1994 |
| P & C Enterprises Limited | Financial services | 2016 |
| P & C Secure Solutions Ltd | Extraterritorial | 2019 |
| P & P Properties NW Ltd | Real estate | 2026 |
| P J S Electrical Contractors (North West) Limited | Construction | 2004 |
| P J Spencer Education Consultant Ltd | Education | 2015 |
| P to the Power of TEN Consulting Ltd | Professional & scientific | 2023 |
| P&M Berkley Ltd | Real estate | 2011 |
| P&R Catering Limited | Hospitality | 2017 |
| P. O'Neill Orthodontics Limited | Health & social care | 2022 |
| P.G.B Coatings Ltd | Manufacturing | 2024 |
| PAC Estates Ltd | Real estate | 2026 |
| PAC Law Limited | Professional & scientific | 2024 |
| Pacgdx Limited | Manufacturing | 2021 |
| Pactive Limited | Information & communication | 2018 |
| Pactive Sports Limited | Administrative & support | 2025 |
| Padua Properties Limited | Real estate | 2002 |
| Paediatric Skin Clinic Dolms Limited | Health & social care | 2026 |
| Paediatric, Perinatal and Placental Pathology Ltd | Health & social care | 2026 |
| PAG Group Services Limited | Manufacturing | 2017 |
| Paint Lounge Ltd | Wholesale & retail | 2025 |
| Palamino N W Ltd | Wholesale & retail | 2015 |
| Paloma Forrest Nurseries Ltd | Wholesale & retail | 2022 |
| Pandora's Box (Ormskirk) Ltd | Wholesale & retail | 2014 |
| Pangea Metal Sculptures Ltd | Manufacturing | 2014 |
| Paradigm First AID Training Limited | Education | 2023 |
| Paradyme Property Management Limited | Real estate | 2022 |
| Paragon Business Services Limited | Administrative & support | 2005 |
| Parcelchex Limited | Extraterritorial | 2008 |
| Parcelminder Limited | Extraterritorial | 2008 |
| Parkleytech Ltd | Information & communication | 2021 |
| Parkside Trading Limited | Other services | 2019 |
| Parkview Property (Lancashire) Limited | Construction | 2015 |
| Parlat Limited | Information & communication | 2006 |
| Partyville Ltd | Arts & recreation | 2020 |
| Parvati Beauty Ltd | Other services | 2020 |
| Pasta 51 Ormskirk Limited | Hospitality | 2023 |
| Pathway Residential Care Ltd | Health & social care | 2025 |