| Tyrone Attic Stairs & Home Improvements Ltd | Construction | 2025 |
| Tyrone Diesel Systems Ltd | Wholesale & retail | 2024 |
| Tyrone Maintenance Services Ltd | Administrative & support | 2023 |
| Tyrone Mortgages Ltd | Financial services | 2023 |
| Tyrone Roofing Contracts Limited | Construction | 2025 |
| Tyrone Services Ltd | Construction | 2019 |
| Tyrone Truck & Trailer Limited | Wholesale & retail | 2012 |
| Tyrone Utilities Ltd | Construction | 2021 |
| U Value Timber Systems Ltd | Manufacturing | 2025 |
| U-Dig (Plant Hire) Limited | | 1989 |
| Udder Health Solutions Limited | Professional & scientific | 2015 |
| Unflatpack Solutions Ltd | Extraterritorial | 2015 |
| Ungaro Services Ltd | Construction | 2023 |
| Unique Massage Ltd | Health & social care | 2026 |
| Uptown Bibi Limited | Wholesale & retail | 2018 |
| Urban Motion C.I.C. | Education | 2023 |
| Urban Motion Holdings Ltd | Professional & scientific | 2024 |
| Urgent Taxis Ltd | Transport & logistics | 2017 |
| V a Generators Limited | Wholesale & retail | 2008 |
| V8 Training Ltd | Education | 2019 |
| Valley Foods Ltd | Wholesale & retail | 2026 |
| Valleyfield Farm Ltd | Agriculture & fishing | 2025 |
| Vault 87 Ltd | Arts & recreation | 2023 |
| Vehicle Solutions N.I Ltd | Wholesale & retail | 2019 |
| Vela Consulting Ltd | Health & social care | 2012 |
| Veyo. Performance Ltd | Wholesale & retail | 2025 |
| Vicon Engineering Ltd | Construction | 2020 |
| Victoria Rentals Ltd | Administrative & support | 2017 |
| VIEW2BUILD Limited | Construction | 2017 |
| Village Pharmacy Limited | Wholesale & retail | 2013 |
| Vincent Dempsey Plant Limited | Administrative & support | 2009 |
| Visiblegy Limited | Information & communication | 2016 |
| Vitalize Omagh Ltd | Other services | 2022 |
| Vivo Derry Road Ltd | Wholesale & retail | 2023 |
| VMB Contracts Ltd | Construction | 2015 |
| Vogue Solutions Hire and Sales Limited | Wholesale & retail | 2015 |
| Volaire Ltd | Wholesale & retail | 2025 |
| W & D Fraser Limited | Households | 1984 |
| W & H Alexander Ltd | Construction | 2013 |
| W H Energy Ltd | Energy | 2014 |
| W KEE Construction Ltd | Manufacturing | 2024 |
| W U Rail Limited | Construction | 2013 |
| Walker Walton Hanson Limited | Professional & scientific | 2021 |
| Wallace & Dickson (Cookstown) Limited | Financial services | 2002 |
| Walters Retail Ltd | Wholesale & retail | 2021 |
| Warnock Healthcare Ltd | Wholesale & retail | 2023 |
| Washpro Ltd | Administrative & support | 2025 |
| Waterside Theatre Company Limited | Arts & recreation | 2010 |
| Waterworx Pipeline and Civils Ltd | Professional & scientific | 2016 |
| Waterworx Robotics Limited | Manufacturing | 2018 |
| Watson & Colhoun (M) Limited | Professional & scientific | 2012 |
| Watson & Colhoun (O) Limited | Professional & scientific | 2012 |
| Watson & Colhoun Omagh Limited | Professional & scientific | 2014 |
| WD Livestock Ltd | Agriculture & fishing | 2016 |
| Weld-Tech Engineering Services Limited | Manufacturing | 2003 |
| Wescom Incubators Ltd | Manufacturing | 2018 |
| West Tyrone Associates Ltd | Real estate | 2009 |
| West Tyrone Rural Limited | | 1996 |
| West View Farms Limited | Agriculture & fishing | 2013 |
| Western Ambulance Service (NI) Ltd | Transport & logistics | 2019 |
| Western Emergency Skills Training Limited | Education | 2019 |
| Westwind Properties Ltd | Households | 2001 |
| WH Agri Limited | Financial services | 2018 |
| WH Tyres & Servicing Ltd | Wholesale & retail | 2023 |
| White Energy Storage Ltd | Energy | 2024 |
| Whitebridge Services Ltd | Agriculture & fishing | 2025 |
| Wholefuel Group Holdings Ltd | Financial services | 2025 |
| Wholefuel Group Ltd | Manufacturing | 2025 |
| Wild Rover Promotions Ltd | Arts & recreation | 2019 |
| Wilkin Plant Hire Ltd | Construction | 2025 |
| Wilkinson Contracts Limited | Construction | 2014 |
| William J. M. Fraser & Co. Limited | Households | 1984 |
| William Keys & Sons Holdings Limited | Wholesale & retail | 2019 |
| William Keys & Sons Ltd | Wholesale & retail | 2019 |
| Wilsons Farms Ltd | Agriculture & fishing | 2022 |
| Windcar Limited | Professional & scientific | 2013 |
| Windtur Ltd | Energy | 2014 |
| Windy Hill Eggs Limited | Agriculture & fishing | 2026 |
| Windy Powers Ltd | Energy | 2015 |
| Windyhall Limited | Real estate | 2007 |
| Witch's Brew Ltd | Hospitality | 2023 |
| WJ Mclaughlin and Sons Limited | Construction | 2013 |
| Wolfie Wildly Nourishing Limited | Manufacturing | 2024 |
| Wood Green Healthcare Limited | Professional & scientific | 2016 |
| Wood Green Management Company (NI) Limited | Health & social care | 2016 |
| Wood Pole Utility Service Ltd | Construction | 2016 |
| Woodbrook Farms Ltd | Agriculture & fishing | 2020 |
| Woodbrook Lodge Farm Ltd | Agriculture & fishing | 2024 |
| Woodland Haulage Ltd | Agriculture & fishing | 2020 |
| Woodvale Construction Company Limited | Construction | 2013 |
| Woodvale Lowry JV Limited | Construction | 2023 |
| Woodvale Residential Limited | Real estate | 2021 |
| Workroom (JT) Ltd | Manufacturing | 2012 |
| WPH Plant Hire and Sales Limited | Administrative & support | 2015 |
| WPH Plant Hire Holdings Ltd | Administrative & support | 2022 |
| Xcat Omagh Ltd | Wholesale & retail | 2018 |
| Xcat the Clearance Company Ltd | Wholesale & retail | 2018 |
| XKV8 NI Ltd | Construction | 2014 |
| Xolve Limited | Wholesale & retail | 2020 |
| Y.A.R. Industries Ltd | Wholesale & retail | 2012 |