| Embassy Auto Hub Limited | Wholesale & retail | 2024 |
| Embelton UK Limited | Manufacturing | 2015 |
| Embers Aquatics CIC | Other services | 2019 |
| Embodyism Limited | Health & social care | 2021 |
| Emck Ltd | Professional & scientific | 2020 |
| Emclo Construction Limited | Construction | 1999 |
| Emclo Developments Limited | Construction | 2004 |
| Emeir Group Ltd | Administrative & support | 2022 |
| Emerald Events MCR Ltd | Other services | 2021 |
| Emerald Goods Ltd | Wholesale & retail | 2024 |
| Emerald SC Private Investments Limited | Real estate | 2026 |
| Emerge Partners Ltd | Professional & scientific | 2020 |
| Emfrs (Filming) Ltd | Public administration | 2015 |
| EMG Energy Consultants Ltd | Extraterritorial | 2014 |
| Emhar Properties Limited | Real estate | 2014 |
| EMI Interiors and Construction Ltd | Construction | 2020 |
| Emilia Gasiorowska Ltd | Health & social care | 2021 |
| Emily Harvey Art Ltd | Professional & scientific | 2021 |
| Eminence Imperial Ltd | Wholesale & retail | 2025 |
| Eminence&Co Ltd | Hospitality | 2020 |
| Eminent Joinery & Maintenance Ltd | Construction | 2021 |
| Eminent Joinery Ltd | Construction | 2022 |
| Eminent Motor Group Ltd | Wholesale & retail | 2020 |
| Emissionszero Ltd | Wholesale & retail | 2021 |
| Emit Services Ltd | Manufacturing | 2022 |
| Emjm Ltd | Other services | 2025 |
| Emma Courtney Real Estate Limited | Real estate | 2025 |
| Emma Healthcare Ltd | Health & social care | 2026 |
| Emmanuel Court (NO. 1) Management Company Limited | Households | 2006 |
| Emmy Jayne's Nursery School Ltd | Education | 2005 |
| Emobilita AZ Electronics Ltd | Wholesale & retail | 2024 |
| EMP Trade Limited | Wholesale & retail | 2023 |
| Emperor of Grace Limited | Wholesale & retail | 2018 |
| EMPEROR24HR Mobile Limited | Health & social care | 2019 |
| Emphasis IT Limited | Information & communication | 2021 |
| Empire Facilities Management Services Ltd | Real estate | 2021 |
| Empire Plates Ltd | Transport & logistics | 2018 |
| Empire Print Solutions Ltd | Manufacturing | 2025 |
| Empire Restaurant & Lounge Limited | Hospitality | 2023 |
| Empire Taxi Solutions Ltd | Transport & logistics | 2015 |
| Empire UK Properties Ltd | Real estate | 2023 |
| Empirical Blue Ltd | Professional & scientific | 2015 |
| Empower ME Studio Ltd | Professional & scientific | 2025 |
| Empower Women Ltd | Health & social care | 2025 |
| Empowered Collective Ltd | Health & social care | 2021 |
| Empowering Together CIC | Public administration | 2025 |
| Emran Property Investments Ltd | Real estate | 2025 |
| Emsa Property & Investments Ltd | Real estate | 2022 |
| Enabling Change Limited | Wholesale & retail | 2001 |
| Enabling Sme's Ltd | Extraterritorial | 2022 |
| Enamel Ltd | Administrative & support | 2017 |
| Enar Solutions Ltd | Professional & scientific | 2026 |
| Enchanted Burger Limited | Hospitality | 2023 |
| Enclave Pharmaceutical Ltd | Health & social care | 2025 |
| Endo 61 Limited | Health & social care | 2009 |
| Endtoend Courier Services Ltd | Transport & logistics | 2025 |
| Enem Marketing Solutions Limited | Information & communication | 2012 |
| Eneo Transport Limited | Transport & logistics | 2026 |
| Energon Cube Limited | Wholesale & retail | 2014 |
| Energy Hydration Recovery Ltd | Wholesale & retail | 2022 |
| Energy Life Ltd. | Health & social care | 2014 |
| Energy Link Solution Limited | Energy | 2026 |
| Enermis Ltd. | Information & communication | 2008 |
| Enersave Pure Solutions Ltd | Other services | 2020 |
| Engine & Transmission Ltd | Wholesale & retail | 2020 |
| Engine Components Limited | Wholesale & retail | 2015 |
| Engine Depot Ltd | Wholesale & retail | 2026 |
| Engines for YOU Ltd | Wholesale & retail | 2022 |
| Engraved Eterna Ltd | Wholesale & retail | 2026 |
| Engreen Environmental Consultants Limited | Professional & scientific | 2002 |
| Enigma FM Ltd | Administrative & support | 2022 |
| ENQ Properties Limited | Real estate | 2024 |
| Enrichiva Ltd | Construction | 2020 |
| Ensure Security Ltd | Administrative & support | 2018 |
| Enterprise Driver Recruitment Limited | Administrative & support | 2014 |
| Enterprise Franchise Services Limited | Administrative & support | 2015 |
| Enterprise Transport Training Limited | Transport & logistics | 2015 |
| Enterprise Web Solutions Limited | Information & communication | 2014 |
| Entwistle Investments Ltd | Real estate | 2024 |
| Entwistleconsultancy Ltd | Other services | 2024 |
| Envero Business Limited | Transport & logistics | 2024 |
| Enviro Windows Oldham Ltd | Construction | 2025 |
| Envirocare Limited | Wholesale & retail | 2008 |
| Environ Insulation Ltd | Construction | 2008 |
| Environmental Water Services Limited | Water & waste | 1990 |
| Envirotrad Pack Ltd | Construction | 2014 |
| Envirox Water Ltd. | Water & waste | 2012 |
| Envision Markets Ltd | Education | 2023 |
| Envy Clothing Ltd | Wholesale & retail | 2025 |
| Envyteck Limited | Professional & scientific | 2024 |
| ENZ Estates Ltd | Real estate | 2021 |
| Enza Consulting Limited | Professional & scientific | 2022 |
| Enza Contracting Ltd | Construction | 2022 |
| Enza Homes Limited | Real estate | 2021 |
| Enza Property Group Limited | Construction | 2020 |
| EOC4CHRIST Ltd | Other services | 2021 |
| EP Medical Limited | Health & social care | 2024 |
| EPC1 James Yarwood Ltd | Professional & scientific | 2026 |
| Epic Label Limited | Professional & scientific | 2025 |
| Epic Merchandise Ltd | Other services | 2019 |