| Sweet Foundations Limited | Real estate | 2025 |
| Sweet Obsession (Oldham) Ltd | Hospitality | 2018 |
| Sweet Treats by Zulaikha Ltd | Administrative & support | 2016 |
| Sweethearts and Desserts Limited | Wholesale & retail | 2022 |
| Sweetspot.Mcr Ltd | Hospitality | 2025 |
| Swift Gear Ltd | Wholesale & retail | 2023 |
| Swift Roofing Cumbria Ltd | Construction | 2026 |
| Swift Taxi Rental Limited | Administrative & support | 2025 |
| Swift Trade Global Ltd | Wholesale & retail | 2025 |
| Swiftnex Ltd | Wholesale & retail | 2026 |
| Swiftroute Solutions Ltd | Wholesale & retail | 2026 |
| Swifts Radio Cars Ltd | Transport & logistics | 2010 |
| Swinton Practice Ltd | Health & social care | 2010 |
| Swinton Travel Limited | Transport & logistics | 2011 |
| Swipe & Buy Ltd | Wholesale & retail | 2025 |
| Swiss Corporate Limited | Other services | 2015 |
| Swiss Summit Ltd | Real estate | 2021 |
| Switched on Electrical (MCR) Ltd | Construction | 2012 |
| SWY Properties Ltd | Households | 2024 |
| Swys Properties Ltd | Households | 2024 |
| Swysh Investments Ltd | Wholesale & retail | 2022 |
| SY Mechanics Ltd | Wholesale & retail | 2025 |
| Sycamore House (Long Lane) Management Company Limited | Real estate | 2002 |
| Sydeen Health Care Limited | Health & social care | 2022 |
| Syed Ahmed Perfumes Ltd | Wholesale & retail | 2025 |
| Syed and Company Oldham Ltd | Professional & scientific | 2021 |
| Syeda Properties Limited | Real estate | 2003 |
| Syeda's Kitchen Ltd | Hospitality | 2023 |
| Sykes Construction Ltd | Construction | 2026 |
| Syktec Ltd | Information & communication | 2020 |
| Sylhet Catering Ltd | Wholesale & retail | 2023 |
| Sylhet Jewellers Ltd | Wholesale & retail | 2024 |
| Sylheti Bazar Limited | Wholesale & retail | 2018 |
| Syltech Limited | Administrative & support | 2013 |
| Sylviasales Ltd | Wholesale & retail | 2026 |
| SYM Property Group Ltd | Real estate | 2019 |
| SYM Retreats Ltd | Hospitality | 2025 |
| Symphony Forte Distribution Ltd | Wholesale & retail | 2019 |
| Synatrix AI Limited | Wholesale & retail | 2025 |
| Synerge Ltd | Information & communication | 2022 |
| Synergy Sprint Ltd | Transport & logistics | 2022 |
| Syngesis C.I.C. | Professional & scientific | 2021 |
| Syntax Controls Limited | Professional & scientific | 2003 |
| Syphon FX Limited | Financial services | 2025 |
| Syslog Limited | Information & communication | 2014 |
| System Design Consultancy Ltd | Information & communication | 2014 |
| System One Guarding Ltd. | Administrative & support | 2014 |
| Sytronix Holdings Limited | Financial services | 2026 |
| Sytronix Limited | Manufacturing | 2021 |
| SZA Services Ltd | Administrative & support | 2024 |
| Szka Ltd | Construction | 2025 |
| Szuaa Limited | Wholesale & retail | 2025 |
| T & C Civil Engineering Ltd | Construction | 2005 |
| T & C Motor Panels Limited | Wholesale & retail | 2010 |
| T & S Metals Limited | Other services | 2014 |
| T Auto's Limited | Administrative & support | 2008 |
| T Barber Properties Ltd | Real estate | 2024 |
| T H Fabrications Limited | Manufacturing | 1998 |
| T Hartley and Co Limited | Wholesale & retail | 2018 |
| T Holden Electrical Ltd | Construction | 2022 |
| T K Collections Ltd | Water & waste | 2026 |
| T L Contractors Limited | Construction | 2017 |
| T P Matrix Limited | Manufacturing | 1996 |
| T P Surfacing Ltd | Construction | 2019 |
| T Worthington Properties Limited | Other services | 2015 |
| T&I Properties Limited | Real estate | 2025 |
| T'S Hire, Recovery & Storage Limited | Other services | 2009 |
| T-Bek Developments Ltd | Construction | 2019 |
| T-W-S Nationwide Ltd | Construction | 2020 |
| T. & a. Installations Ltd. | Construction | 2022 |
| T. Athorn Mouldmakers Limited | | 1982 |
| T. Collins & SON Limited | Other services | 1997 |
| T.Electronics UK West Africa Ltd | Construction | 2020 |
| T.S Dent Removal Ltd | Wholesale & retail | 2026 |
| T.V. & E. Mcpartland Limited | Manufacturing | 1975 |
| T20 Darts Oldham Ltd | Wholesale & retail | 2022 |
| T9 Digital Ltd | Wholesale & retail | 2018 |
| T92 Limited | Wholesale & retail | 2025 |
| Ta.Ka Investments Ltd | Real estate | 2025 |
| TA9 Limited | Hospitality | 2024 |
| TA9 Property Ltd | Real estate | 2024 |
| Taabi Enterprises Ltd | Wholesale & retail | 2026 |
| Table Angels and Event Creations Ltd | Arts & recreation | 2019 |
| Tadeusz Building Services Ltd | Construction | 2018 |
| TAG Manchester Ltd | Professional & scientific | 2018 |
| TAG Technology UK Ltd | Professional & scientific | 2008 |
| Tagged Resources Ltd | Administrative & support | 2010 |
| Taglec Electrical Contractors Limited | Construction | 2016 |
| Taharah Services Ltd | Administrative & support | 2024 |
| Tahir Halal Meat & Poultry Ltd | Wholesale & retail | 2025 |
| Tahm Trading Ltd | Wholesale & retail | 2025 |
| TAI Optics Limited | Health & social care | 2025 |
| Tailored Climbing Wall Solutions Ltd | Arts & recreation | 2013 |
| Tailored-Ot Ltd | Health & social care | 2022 |
| Taimo Limited | Wholesale & retail | 2026 |
| TAJ Balti House Limited | Hospitality | 2019 |
| TAJ Royton Ltd | Hospitality | 2026 |
| Takk Hire Ltd | Administrative & support | 2024 |
| Tala Transport Limited | Transport & logistics | 2017 |
| Talbot Street North Management Limited | Real estate | 2009 |