| Red Rose Valeting Limited | Administrative & support | 2022 |
| Red Squirrel Investments Limited | Real estate | 2019 |
| Red Visual Content Production Ltd | Information & communication | 2024 |
| Redbeam Limited | Manufacturing | 2020 |
| Redbrick UK Limited | Administrative & support | 2002 |
| Reddish Demolition Limited | Construction | 1959 |
| Reddish Training Limited | Education | 2020 |
| Reddish Vale Insulations Limited | Water & waste | 1984 |
| Redeem Capital Ltd | Administrative & support | 2023 |
| Redfern Homes Middleton Limited | Real estate | 2025 |
| Redfern Roofcare Ltd | Construction | 2025 |
| Redfox Countryside Services Ltd | Other services | 2016 |
| Redfox Property Lettings and Management Ltd | Real estate | 2018 |
| Redgalaxy Ltd | Professional & scientific | 2011 |
| Rediscover Wines Ltd | Wholesale & retail | 2021 |
| Redland Roofing Services Ltd | Construction | 2026 |
| Redline Prestige Ltd | Wholesale & retail | 2025 |
| Redmonds Solicitors Limited | Professional & scientific | 2006 |
| Rednevada Technology Limited | Information & communication | 2023 |
| Redrosecomposites Ltd | Manufacturing | 2022 |
| Reds Gym Limited | Arts & recreation | 2022 |
| Redstone Ridge Commerce Ltd | Wholesale & retail | 2026 |
| Redtec (UK) Limited | Wholesale & retail | 2005 |
| Redwaves Ltd | Wholesale & retail | 2025 |
| Redwood Commercial Vehicles Ltd | Wholesale & retail | 2022 |
| Redwood Construction (Saddleworth) Limited | Construction | 2009 |
| Redwood Manufacturing Limited | Administrative & support | 2019 |
| REE Ming Ltd | Hospitality | 2013 |
| Reed Turbines Ltd | Construction | 2021 |
| Reed Ward Properties Ltd | Administrative & support | 2019 |
| Reedward Plastics NW Ltd | Wholesale & retail | 2015 |
| Reel Appeal Limited | Manufacturing | 2004 |
| Reel Issues Creative Limited | Professional & scientific | 2026 |
| Reevex Ltd | Wholesale & retail | 2025 |
| Refine Engineering Ltd | Professional & scientific | 2025 |
| Refined Luxury Decorating Ltd | Construction | 2025 |
| Refinery-Supplies Limited | Manufacturing | 1987 |
| Reflection Home Improvements Limited | Construction | 2008 |
| Reform Kitchen Limited | Hospitality | 2020 |
| Refresh Cleaning Services (NW) Ltd | Administrative & support | 2026 |
| Refresh Refresh Ltd | Administrative & support | 2023 |
| Refrigeration House Limited | Financial services | 2024 |
| Refurb Car Cosmetics Ltd | Wholesale & retail | 2025 |
| Rega Supermarket Limited | Wholesale & retail | 2023 |
| Regal (Shaw) Ltd | Manufacturing | 1973 |
| Regal Achievers Educational Ltd | Professional & scientific | 2024 |
| Regal Effects Facility Management and Property Developers Limited | Construction | 2024 |
| Regal Partners Ltd | Wholesale & retail | 2024 |
| Regal X Ltd | Information & communication | 2025 |
| Regalbourne Developments Limited | Real estate | 2003 |
| Regan & Mason Estates Ltd | Real estate | 2020 |
| Regen Digital Ltd | Information & communication | 2024 |
| Regency Parking Solutions Ltd | Transport & logistics | 2024 |
| Regency Parking Solutions NW Ltd | Transport & logistics | 2024 |
| Regenerate EI Ltd | Administrative & support | 2024 |
| Regenerate IE Ltd | Administrative & support | 2026 |
| Regent Group Ltd | Transport & logistics | 2017 |
| Regent Medical Americas Holdings Limited | Professional & scientific | 2004 |
| Regent Medical Limited | Health & social care | 2004 |
| Regent Medical Overseas Limited | Health & social care | 2004 |
| Regional Advice Limited | Administrative & support | 2015 |
| Regional Steels (UK) Limited | Manufacturing | 2009 |
| Regional Steels Holdings Ltd | Financial services | 2019 |
| Regitek Entry Systems Ltd | Construction | 2025 |
| Regvo Ltd | Information & communication | 2025 |
| Rehab Store Ltd | Wholesale & retail | 2026 |
| Rehmaa Ltd | Wholesale & retail | 2025 |
| Rehman Brothers Limited | Real estate | 2023 |
| Rehmat Khan Collections Limited | Wholesale & retail | 2025 |
| Reic Limited | Real estate | 2015 |
| Reid Building Consultants Ltd | Professional & scientific | 2019 |
| Reiki Tradition School of Reiki Ltd | Education | 2026 |
| Relative Holdings Ltd | Financial services | 2025 |
| Relaxstays Ltd | Real estate | 2024 |
| Reliable Airport Transfers Ltd | Transport & logistics | 2024 |
| Reliantecommerce Ltd | Wholesale & retail | 2024 |
| Remap ECU Ltd | Manufacturing | 2026 |
| Remarkables South North JVS Limited | Real estate | 2018 |
| Remedian IT Solutions Limited | Information & communication | 2013 |
| Remedian Ltd | Real estate | 2007 |
| Remote 24 Care Ltd | Public administration | 2025 |
| Remotion Media Ltd | Information & communication | 2022 |
| Removal 24/7 Ltd | Water & waste | 2026 |
| Removal Services MCR Ltd | Transport & logistics | 2025 |
| Renair Conditioning and Refrigeration Ltd | Construction | 2019 |
| Renato Constantin Ltd | Transport & logistics | 2020 |
| Renato&Ranato Construction Limited | Construction | 2026 |
| Renegade Motors Ltd | Wholesale & retail | 2025 |
| Renegade Motorz Ltd | Wholesale & retail | 2025 |
| Reness Dance Troupe CIC | Arts & recreation | 2026 |
| Renewable Hydrocarbons Limited | Professional & scientific | 2009 |
| Renfab Limited | Manufacturing | 2020 |
| Rent Solutions Limited | Financial services | 2007 |
| Renteazy Equipment Solution UK Ltd | Wholesale & retail | 2024 |
| Rentorahiregroup Ltd | Administrative & support | 2026 |
| Rentoro Limited | Real estate | 2024 |
| Rentwise Homes Ltd | Real estate | 2024 |
| Repair Today Ltd | Construction | 2025 |
| Repave Ltd | Construction | 2024 |
| Repton HR Ltd | Administrative & support | 2024 |