| DAD & Baby Limited | Information & communication | 2024 |
| Dale Chadwick Carpentry & Construction Ltd | Construction | 2019 |
| Daniel G King Limited | Information & communication | 2009 |
| Darcy Heard Properties Ltd | Construction | 2022 |
| Dart FM Services Ltd | Administrative & support | 2022 |
| Dart Supplies Ltd | Wholesale & retail | 2024 |
| Dartmoor Active Leisure Ltd. | Hospitality | 1997 |
| Dartmoor Auctions 2024 Limited | Wholesale & retail | 2024 |
| Dartmoor Auctions Limited | Other services | 2016 |
| Dartmoor Cottages Limited | Real estate | 2025 |
| Dartmoor Dens Ltd | Construction | 2025 |
| Dartmoor Domestic Appliance Repairs Ltd | Other services | 2023 |
| Dartmoor Grange Okehampton Management Company Limited | Households | 2006 |
| Dartmoor Great Stays Ltd | Real estate | 2020 |
| Dartmoor Masonry Ltd | Construction | 2020 |
| Dartmoor Multi Academy Trust | Education | 2017 |
| Dartmoor Property Management Ltd | Real estate | 2024 |
| Dartmoor Property Services Ltd | Real estate | 2021 |
| Dartmoor Scaffolding Ltd | Construction | 2024 |
| Dartmoor Software Limited | Information & communication | 2018 |
| Dave Baskerville Building Services Ltd | Construction | 2025 |
| Dave Parsons Ltd | Professional & scientific | 2019 |
| Dave Wills Catering Limited | Hospitality | 2015 |
| David Trant Limited | Wholesale & retail | 2009 |
| Davies Holdings (Somerton) Limited | Real estate | 1985 |
| DB Materials Consulting Limited | Professional & scientific | 2014 |
| DE Lucy Homes Limited | Real estate | 2022 |
| Deadline Tracker Limited | Information & communication | 2019 |
| Demand Creation Services Limited | Professional & scientific | 2025 |
| Dennis Construction Limited | Construction | 2014 |
| Derek Price Consulting Ltd. | Professional & scientific | 2019 |
| Deshi Chai Ltd | Hospitality | 2025 |
| Devon Hedge Group C.I.C. | Agriculture & fishing | 2022 |
| Devon Trade Car Centre Ltd | Wholesale & retail | 2025 |
| Diagram Visual Information Limited | Information & communication | 1972 |
| DIG IT Services Sussex Ltd | Construction | 2008 |
| Digital Character Games Ltd | Arts & recreation | 2014 |
| Digital Fashion World Ltd | Extraterritorial | 2015 |
| DIY Supplies (Okehampton) Limited | Extraterritorial | 2005 |
| Documanagement Consultancy Ltd | Administrative & support | 2017 |
| Domi Star Bubble Ltd | Wholesale & retail | 2024 |
| Donalds Menswear (Okehampton) Ltd | Wholesale & retail | 2016 |
| Donaldson Livestock Limited | Agriculture & fishing | 2017 |
| Donna Pease Ltd | Wholesale & retail | 2024 |
| Down at Hele Limited | Energy | 2010 |
| Drexim Limited | Other services | 1977 |
| Dunn Brothers Limited | Manufacturing | 2004 |
| Durafell Limited | Wholesale & retail | 2025 |
| DWW Ltd | Real estate | 2020 |
| Dynamic Cladding Limited | Construction | 2012 |
| E & O Warehousing Limited | Transport & logistics | 1975 |
| Earthwise Ventures Ltd | Construction | 2024 |
| East Devon Aesthetics Ltd | Health & social care | 2023 |
| Ebusiness Management and Marketing Ltd | Information & communication | 2015 |
| Echoes.Xyz Ltd | Information & communication | 2015 |
| Edgar Enterprises Ltd | Extraterritorial | 2017 |
| Edgemoor Properties Ltd | Real estate | 2020 |
| Edgemoor Property Management Ltd | Real estate | 2026 |
| Education Publishing Worldwide Limited | Information & communication | 2001 |
| Edwinson Green & Sons Limited | Wholesale & retail | 2002 |
| EGD Partners Ltd | Professional & scientific | 2021 |
| EGO to Eco | Professional & scientific | 2021 |
| EHF Property Ltd | Households | 2025 |
| EJB Deliveries Ltd | Transport & logistics | 2015 |
| Elemental Micro-Analysis Limited | Manufacturing | 1976 |
| Elena’S Beauty Ltd | Other services | 2026 |
| Elkins Consultancy Limited | Administrative & support | 2017 |
| Ellis Bakery Ltd | Manufacturing | 2017 |
| Ellis Imagery Ltd | Professional & scientific | 2010 |
| Ellis Oakmoor Ltd | Real estate | 2026 |
| Emily Smith Ltd | Wholesale & retail | 2018 |
| Enchanted House Beds Limited | Manufacturing | 2014 |
| Encompass Training South West Limited | Arts & recreation | 2009 |
| Enderson Commercial Ltd | Construction | 2004 |
| Endworth Developments Limited | Real estate | 2005 |
| Ensquared IT Solutions Ltd | Information & communication | 2026 |
| Equafleece Limited | Manufacturing | 2006 |
| Equafleece Trustees Limited | Professional & scientific | 2023 |
| Equi-Tots Ltd | Wholesale & retail | 2023 |
| Equine and Canine Sports Therapy Limited | Wholesale & retail | 2015 |
| ESS Woods Ltd | Professional & scientific | 2017 |
| Essential Online Traders Ltd | Wholesale & retail | 2019 |
| Essworthy Estates Limited | Agriculture & fishing | 2000 |
| EVE Oliveira BR Ltd | Education | 2023 |
| Eversfield Manor Ltd | Hospitality | 2013 |
| Eversfield Organic Retail Ltd | Wholesale & retail | 2018 |
| Exbourne Cross Garage Limited | Wholesale & retail | 2018 |
| Exeter Community Basketball Club Ltd | Education | 2026 |
| F&C Associates Limited | Professional & scientific | 2026 |
| F. J. Glass & Co. (1981) Limited | Wholesale & retail | 1981 |
| F.W. Yelland & SON (Northlew) Limited | Manufacturing | 1978 |
| Fairground Heritage Trust(The) | Arts & recreation | 1986 |
| Falmouth GIN Limited | Manufacturing | 2018 |
| FAR Frontiers Travel Limited | Administrative & support | 2006 |
| Farr Management Limited | Professional & scientific | 2019 |
| Farrar Trading Ltd | Wholesale & retail | 2024 |
| Fascination Coaching C.I.C. | Education | 2023 |
| Fast Dash Limited | Transport & logistics | 2021 |
| Fernley YEO Limited | Administrative & support | 1988 |
| Fewings & Hughes Limited | Construction | 2021 |