| Dream Exports Ltd | Wholesale & retail | 2026 |
| Dream Party Decor Limited | Hospitality | 2015 |
| Driftwood Van Conversions Ltd | Wholesale & retail | 2024 |
| Drillability Limited | Extraterritorial | 2001 |
| Drink Lomi Ltd | Wholesale & retail | 2025 |
| Drinkwise Hospitality Ltd | Hospitality | 2026 |
| Drivebeam Limited | Other services | 2003 |
| Driveora Motors Limited | Wholesale & retail | 2026 |
| Driver Force Recruitment Limited | Administrative & support | 2017 |
| Driving Joy Ltd. | Arts & recreation | 2018 |
| Drop Shot Padel Ltd | Arts & recreation | 2024 |
| Drops of Jupiter Ltd | Other services | 2024 |
| DRS Family Ltd | Real estate | 2025 |
| Drummotors and More Limited | Wholesale & retail | 2003 |
| Dry-It-Out Limited | Energy | 2003 |
| DS28 Properties Limited | Real estate | 2024 |
| DSF Engineering Design Ltd | Professional & scientific | 2024 |
| Dsjkk Limited | Real estate | 2025 |
| DSO Design Solutions Ltd | Professional & scientific | 2023 |
| DSS Services Ltd | Wholesale & retail | 2025 |
| DT Products Limited | Wholesale & retail | 2024 |
| Dt&Sons Construction Ltd | Construction | 2025 |
| DTA Bricklaying Solutions Ltd | Construction | 2024 |
| DTM Automation Ltd | Professional & scientific | 2015 |
| DTP4ALL Ltd | Manufacturing | 2026 |
| Duality Media Limited | Information & communication | 2017 |
| Dublaid Industries Ltd | Professional & scientific | 2025 |
| Dubsta LLP | | 2025 |
| Dudek Driver Limited | Transport & logistics | 2019 |
| Dudu Studios Ltd | Professional & scientific | 2022 |
| Dudugeotech Ltd | Construction | 2018 |
| Duel Group Ltd | Wholesale & retail | 2025 |
| Dugdale Investments Limited | Real estate | 1961 |
| Duggystone Media House Ltd | Information & communication | 2018 |
| Duka International Limited | Wholesale & retail | 2017 |
| Dunns Lane Property Limited | Real estate | 2021 |
| Duon Global Services LLC Limited | Other services | 2017 |
| Duradent Dental Group Limited | Health & social care | 2025 |
| Duradent Ltd | Health & social care | 2018 |
| Dustzero Cleaning Solutions Ltd | Administrative & support | 2026 |
| DV Properties Limited | Real estate | 2020 |
| DVC Local Store Ltd | Wholesale & retail | 2024 |
| DVC Taxi Limited | Transport & logistics | 2023 |
| DVR Logistics Ltd | Transport & logistics | 2022 |
| DVW Holdings Ltd | Financial services | 2025 |
| DW Trucking Limited | Transport & logistics | 2012 |
| DW77 Limited | Wholesale & retail | 2026 |
| Dwelling Evolution Ltd | Households | 2025 |
| Dwellio Ltd | Real estate | 2023 |
| Dwsk Holdings Limited | Financial services | 2022 |
| Dyble Reah (Group) Limited | Financial services | 2025 |
| Dynamic Gaming Limited | Administrative & support | 2002 |
| Dynamic Housing Solutions Ltd | Real estate | 2024 |
| Dynasty & Prestige Events Hire Limited | Administrative & support | 2023 |
| Dynetic Homes and Gardens LLP | | 2024 |
| Dynetic Homes Limited | Real estate | 2022 |
| Dynetic Limited | Information & communication | 2017 |
| DZD Reporting Limited | Health & social care | 2024 |
| E & P Properties (Nuneaton) Limited | Real estate | 2024 |
| E P Bearings Limited | Wholesale & retail | 2004 |
| E&E Work Ltd | Transport & logistics | 2025 |
| E&T IT Solutions Limited | Information & communication | 2020 |
| E&T Social Care Ltd | Health & social care | 2025 |
| E-Plas Supplies Limited | Manufacturing | 2007 |
| E-Solv Ltd | Professional & scientific | 2012 |
| E.D.C. Developments Ltd | Manufacturing | 2010 |
| E.S.J Services Ltd | Construction | 2024 |
| E.W. Blood & Sons Limited | Agriculture & fishing | 1962 |
| EAE Engineering Ltd | Professional & scientific | 2017 |
| Eagle Properties Management Ltd | Hospitality | 2020 |
| Eagles Tribe Ltd | Construction | 2017 |
| Eales Properties Ltd | Real estate | 2022 |
| Easa Group Limited | Real estate | 2016 |
| Eastboro Court Management Company Limited | Households | 1990 |
| Easyline Roofing & Guttering Ltd | Construction | 2025 |
| EAT Real Co 2 Ltd | Manufacturing | 2020 |
| EAT Real Ltd | Manufacturing | 2020 |
| EB HR Solutions Limited | Administrative & support | 2026 |
| EC Trade Cars Ltd | Wholesale & retail | 2024 |
| Ecas Academic Limited | Education | 2024 |
| Eccleston Financial Services Ltd | Financial services | 2018 |
| Echos Laser Treatments Ltd | Health & social care | 2023 |
| Eclipse Europe (Logistics) Ltd | Transport & logistics | 2010 |
| Eco Iris of Properties Limited | Real estate | 2023 |
| Ecomium Ltd | Wholesale & retail | 2026 |
| Ecopiers Ltd | Wholesale & retail | 2025 |
| ED Line Limited | Arts & recreation | 2016 |
| Eden Afro-Caribbean Food Superstore Ltd | Wholesale & retail | 2025 |
| Edge Agricultural Limited | Financial services | 2019 |
| Edge Camps UK Ltd | Health & social care | 2025 |
| Edge Drivers Ltd | Transport & logistics | 2018 |
| EDUC8 Business Consultancy Limited | Financial services | 2010 |
| EDUC8 Coventry & Warwickshire Ltd | Education | 2011 |
| EDUC8 Leicestershire Limited | Education | 2009 |
| EDUC8 Northumberland Ltd | Education | 2013 |
| EDUC8 Redcar Ltd | Education | 2013 |
| Edward Davenport Learning and Development Specialist Limited | Education | 2018 |
| Edward Davies Chiropractic Ltd | Health & social care | 2010 |
| Edwards Financial Planning Ltd | Professional & scientific | 2021 |
| Edwards Holiday Lets Limited | Real estate | 2023 |