| Stable Door Associates Limited | Professional & scientific | 2013 |
| Stack 15 Limited | Extraterritorial | 2015 |
| Stacked OUT Limited | Information & communication | 2009 |
| Stacksoft Limited | Information & communication | 2021 |
| Stackyard Property Limited | Real estate | 2014 |
| Stackz Limited | Hospitality | 2025 |
| Stacris Ltd | Wholesale & retail | 2025 |
| STAFF44 Ltd | Administrative & support | 2015 |
| Staffconnect Ltd | Administrative & support | 2022 |
| Staffline Group PLC | Administrative & support | 2004 |
| Staffline Limited | Extraterritorial | 2009 |
| Staffline Recruitment (NI) Limited | Administrative & support | 1984 |
| Staffline Recruitment Limited | Administrative & support | 2000 |
| Stafflink Go Solutions Ltd | Transport & logistics | 2025 |
| Stafford House (Stoke) Limited | Construction | 2020 |
| Stafford V.E. Limited | Other services | 1995 |
| Staffordshire Canine Confidence Ltd | Other services | 2024 |
| Staffordshire Wood Finishing Limited | Manufacturing | 2022 |
| Staffroom Limited | Administrative & support | 2000 |
| Staffroompro Ltd | Information & communication | 2026 |
| Stag & Thistle Finishes Ltd | Construction | 2025 |
| Stag Electrical Services Ltd | Construction | 2023 |
| Stag Lettings and Property Limited | Households | 2026 |
| Stag Property Improvements Limited | Construction | 2019 |
| Stag Stores Limited | Wholesale & retail | 2011 |
| Stag VHC Limited | Administrative & support | 2026 |
| Stage Link International Ltd | Arts & recreation | 2025 |
| Stage Ride Support Ltd | Wholesale & retail | 2022 |
| Stageheads Ltd | Arts & recreation | 2018 |
| Stagfield Group Ltd | Construction | 2017 |
| Stagyes International Ltd | Wholesale & retail | 2017 |
| Stainless Steel Designs Limited | Manufacturing | 2001 |
| Stainless Steel Sinks Limited | Wholesale & retail | 2012 |
| Stainless Tanks Limited | Manufacturing | 2011 |
| Stainsby Residential Limited | Real estate | 2021 |
| Stainton Engineering Consultants Ltd | Professional & scientific | 2019 |
| Staircase Renovation Ltd | Manufacturing | 2019 |
| Stairmand Property Limited | Real estate | 2020 |
| Stalldor Limited | Wholesale & retail | 2021 |
| Stallion Academy Ltd | Wholesale & retail | 2023 |
| Stallion Trading Limited | Wholesale & retail | 2005 |
| Stalwart Close Protection Ltd | Administrative & support | 2026 |
| Stam Construction Limited | Construction | 1999 |
| Stam Structures Limited | Extraterritorial | 2014 |
| Stamford Fisher Ltd | Wholesale & retail | 2019 |
| Stamford Healthcare Limited | Health & social care | 2022 |
| Stamford LEA Residents Management Company | Households | 2023 |
| Stamford V.E. Limited | Other services | 1995 |
| Stammers Matter CIC | Education | 2025 |
| Stammers Property Holdings Limited | Real estate | 2026 |
| Stamp Home Development Ltd | Construction | 2016 |
| Stamp Marketing Ltd | Professional & scientific | 2019 |
| Stamp Property Development Ltd | Construction | 2016 |
| Stan Berra Developments Ltd | Construction | 2022 |
| Stan Berra Ltd | Real estate | 2022 |
| Stan Trade Limited | Wholesale & retail | 2024 |
| Stan Worldwide Limited | Manufacturing | 2019 |
| Stan's Pals Pet Services Limited | Agriculture & fishing | 2018 |
| Stanbos Solutions Limited | Real estate | 2025 |
| Stanchion Group Limited | Professional & scientific | 2026 |
| Stand Consultancy Ltd | Professional & scientific | 2025 |
| Standard Consulting & Training Ltd | Professional & scientific | 2025 |
| Standard Engineering Plastics Limited | Extraterritorial | 1969 |
| Standard Hill Properties Limited | Real estate | 2025 |
| Standard Life Investment Services Limited | Extraterritorial | 1989 |
| Standard Wire Gauge Ltd | Professional & scientific | 2023 |
| Standby Events Limited | Administrative & support | 2009 |
| Standen Construction Limited | Wholesale & retail | 1967 |
| Standford Healing Ministry Ltd | Administrative & support | 2020 |
| Standhill Stores Ltd | Wholesale & retail | 2025 |
| Standogs Ltd | Agriculture & fishing | 2025 |
| Standyby Ltd | Administrative & support | 2026 |
| Stanford Gould Limited | Administrative & support | 2018 |
| Stanford Shelf Company NO. 2 Limited | Financial services | 2018 |
| Stanford Street NO. 1 Limited | Real estate | 2014 |
| Stanfra Property Holdings Ltd | Real estate | 2019 |
| Stanhope Dene Ltd | Professional & scientific | 2018 |
| Stanislaw Latka Ltd | Information & communication | 2023 |
| Stanley & Co Accountants Ltd | Professional & scientific | 2024 |
| Stanley & Livingstone Limited | Professional & scientific | 2012 |
| Stanley Empire Limited | Construction | 2011 |
| Stanley House Lettings Ltd | Real estate | 2019 |
| Stanley Osmond Limited | Health & social care | 2019 |
| Stanley Paws Limited | Households | 2022 |
| Stanley Property Group Ltd | Real estate | 2021 |
| Stannard Daly Properties Ltd | Real estate | 2017 |
| Stannier Electrical Ltd | Construction | 2023 |
| Stanningley Pharma Limited | Wholesale & retail | 2010 |
| Stanpro Ltd | Health & social care | 2019 |
| Stanton & Glebe Ltd | Information & communication | 2026 |
| Stanton Executive Solutions Ltd | Administrative & support | 2021 |
| Stanton Facilities Management Ltd | Households | 2013 |
| Stanton Hill Progressive Club Ltd | Hospitality | 2020 |
| Stanton Lane Investments Limited | Financial services | 2018 |
| Stanton-On-The-Wolds Golf Club Limited | Arts & recreation | 1928 |
| Stanue Properties Ltd | Real estate | 2018 |
| Stapleford Aluminium Limited | Manufacturing | 1981 |
| Stapleford and Sandiacre M.O.T Limited | Wholesale & retail | 2019 |
| Stapleford CUE Club Limited | Arts & recreation | 2015 |
| Stapleford Plumbing Services Ltd | Construction | 2012 |