| Sandrail Limited | Professional & scientific | 1996 |
| Sandwell College Management Company Limited | Households | 2005 |
| Sandwood Securities Limited | Real estate | 1965 |
| Sandy Lane Resort Limited | Hospitality | 2011 |
| Sandyplot Limited | Real estate | 1991 |
| Sane (Midlands) Investments Limited | Financial services | 2022 |
| Sanford Group Limited | Manufacturing | 2017 |
| Sanger Convenience Store Ltd | Wholesale & retail | 2024 |
| Sanger Property Limited | Real estate | 2021 |
| Sanger Stores Limited | Wholesale & retail | 2025 |
| Sanghera Investments Limited | Real estate | 2016 |
| Sanham Farm Limited | Agriculture & fishing | 1956 |
| Sani AA Construction Ltd | Construction | 2015 |
| Sani Builders Ltd | Construction | 2024 |
| Sanisure Acquisition Company Limited | Professional & scientific | 2015 |
| Sanisure Europe Ltd. | Financial services | 2019 |
| Sanisure Intermediateco 2 Ltd | Financial services | 2019 |
| Sanisure Limited | Manufacturing | 1979 |
| Sanita's Flowers Limited | Wholesale & retail | 2023 |
| Sanitas Group Limited | Administrative & support | 2025 |
| Sanitas Property Services Ltd | Transport & logistics | 2024 |
| SANITAS2SUCCESS Ltd | Wholesale & retail | 2024 |
| Sanity Services Limited | Administrative & support | 2004 |
| Sanjha House Ltd | Health & social care | 2025 |
| Sankofa Education Limited | Education | 2011 |
| Sankofa Exchange Limited | Real estate | 2011 |
| Sankofa Financial Services Limited | Professional & scientific | 2011 |
| Sankofa Group Limited | Real estate | 2011 |
| Sankofa Legal Services Limited | Professional & scientific | 2011 |
| Sanman Investments Limited | Real estate | 2007 |
| Sanmedia Tech Solutions Ltd | Information & communication | 2024 |
| Sannico Service Station Limited | Wholesale & retail | 2006 |
| Sanotio Ltd | Health & social care | 2023 |
| Sanrav Consultancy Limited | Information & communication | 2017 |
| Sanrose Group PVT Limited | Health & social care | 2015 |
| Sans Boyle Ltd | Real estate | 2026 |
| Sans Consulting (UK) Ltd | Real estate | 2024 |
| Sans Patrie Ltd | Hospitality | 2019 |
| Sans Trent Ltd | Wholesale & retail | 2025 |
| Sans Vape Ltd | Wholesale & retail | 2024 |
| Sansar UK Limited | Information & communication | 2007 |
| Sansin Ltd | Real estate | 2023 |
| Sant Developments Limited | Construction | 2023 |
| Santo ADO Ltd | Construction | 2025 |
| Santorini (Bidco) Limited | Administrative & support | 2022 |
| Santorini (Midco 1) Limited | Administrative & support | 2022 |
| Santorini (Midco 2) Limited | Administrative & support | 2022 |
| Santorini (Topco) Limited | Administrative & support | 2022 |
| Santullo Service Limited | Health & social care | 2018 |
| Sanve Care Limited | Health & social care | 2020 |
| Sanvia Recruitment Ltd | Administrative & support | 2025 |
| Sanyaz Sparkle Cleaning Services Limited | Administrative & support | 2023 |
| Saolré Ltd | Professional & scientific | 2023 |
| Sapa Ltd | Other services | 2024 |
| Sapien ARC Ltd | Information & communication | 2020 |
| Sapien Solutions Ltd | Real estate | 2024 |
| Sapien Works Ltd | Professional & scientific | 2025 |
| Sapientia Solutions Ltd | Information & communication | 2009 |
| Saplus Consulting Ltd | Information & communication | 2014 |
| Sapphire Prestige Ltd | Real estate | 2025 |
| Sapphire Financial Solutions (Nottingham) Ltd | Professional & scientific | 2020 |
| Sapphire Group Inc Ltd | Financial services | 2024 |
| Sapphire Hair and Beauty Boutique Ltd | Other services | 2024 |
| Sapphire Home Designs Ltd | Professional & scientific | 2024 |
| Sapphire Home Improvements (Nottingham) Limited | Construction | 2010 |
| Sapphire Nails (Belper) Ltd | Other services | 2022 |
| Sapphire Property Holdings Limited | Real estate | 2018 |
| Sapphire Property Investments and Ventures Ltd | Real estate | 2019 |
| Sapphire Property Mentors Ltd | Education | 2024 |
| Sapphire Telecom Consulting Limited | Information & communication | 2007 |
| Sapphire Trade Limited | Administrative & support | 2014 |
| Sapphirepink Ltd | Manufacturing | 2021 |
| Sapphiro Books Ltd | Information & communication | 2023 |
| Sapra Holdings Limited | Financial services | 2017 |
| Saptrix Limited | Information & communication | 2004 |
| Saqa Properties Ltd | Real estate | 2018 |
| Saqfar Limited | Wholesale & retail | 2025 |
| SAR Engineering Supplies Ltd | Wholesale & retail | 2025 |
| Sara Conglomerates (UK) Limited | Manufacturing | 2025 |
| Sara Vagvolgyi Limited | Health & social care | 2025 |
| Saracens Notts Ltd | Education | 2025 |
| Saracens Securities Limited | Construction | 1969 |
| Sarach Ltd | Wholesale & retail | 2025 |
| Sarafi Fathi Ltd | Financial services | 2025 |
| Sarah 1997 Ltd | Health & social care | 2012 |
| Sarah Bath Ltd | Wholesale & retail | 2008 |
| Sarah Churm Management Limited | Arts & recreation | 2018 |
| Sarah Clark-Martin Consulting Limited | Professional & scientific | 2015 |
| Sarah Dale Designs Ltd | Professional & scientific | 2025 |
| Sarah Deakin Limited | Construction | 2012 |
| Sarah Estates Ltd | Real estate | 2025 |
| Sarah Jane Linley Hair Ltd | Other services | 2026 |
| Sarah L Roberts Limited | Financial services | 2021 |
| Sarah Mann Shaw Limited | Health & social care | 2013 |
| Sarah Mazzei Limited | Wholesale & retail | 2025 |
| Sarah Young Consulting and Coaching Limited | Other services | 2014 |
| Sarah's Housekeeping Ltd | Administrative & support | 2025 |
| Sarah's Swim School Ltd | Education | 2017 |
| Sarakenoi Limited | Other services | 2022 |
| Sarali Homes Ltd | Health & social care | 2018 |