| DR Helen Curran Coaching & Consultancy Ltd | Professional & scientific | 2022 |
| DR HJ Ltd | Information & communication | 2026 |
| DR JAS Clinics Limited | Health & social care | 2022 |
| DR Jess Training Ltd | Education | 2026 |
| DR K Latief Associates Ltd. | Health & social care | 2011 |
| DR Khan Limited | Health & social care | 2021 |
| DR Malaika Clinics Limited | Health & social care | 2021 |
| DR Marcellus BAZ BEM Consultancy Ltd | Professional & scientific | 2025 |
| DR Maruthi Limited | Health & social care | 2024 |
| DR Montio Morgan Ltd | Health & social care | 2018 |
| DR Paiva Ltd | Health & social care | 2025 |
| DR Paul Limited | Wholesale & retail | 2025 |
| DR Projects Limited | Real estate | 2013 |
| DR R Hussain Medical Services Ltd | Health & social care | 2025 |
| DR Rabi Aesthetics Ltd | Health & social care | 2024 |
| DR Rishi Shah Ltd | Health & social care | 2023 |
| DR Sande Reporting Co. Ltd | Health & social care | 2020 |
| DR Scoots Ltd | Manufacturing | 2023 |
| DR Scrap Metal Ltd | Wholesale & retail | 2022 |
| DR Shayda K Ltd | Health & social care | 2023 |
| DR Skulpt Ltd | Education | 2022 |
| DR Smile Limited | Health & social care | 2020 |
| DR SSU Ltd | Health & social care | 2022 |
| DR Taha Adamji Ltd | Health & social care | 2024 |
| DR VL Webster Ltd | Health & social care | 2019 |
| DR. Aiste Audickaite Limited | Health & social care | 2021 |
| DR. Montio Morgan Property Ltd | Real estate | 2020 |
| Drac (UK) Ltd | Construction | 2014 |
| Dracs Energy Limited | Manufacturing | 2023 |
| Drafting and Design Centre Limited | Professional & scientific | 2003 |
| Dragon Advisory Limited | Extraterritorial | 2012 |
| Dragon Structural Ltd | Professional & scientific | 2018 |
| Dragon Tooth Limited | Health & social care | 2009 |
| Dragon Wells Ltd | Hospitality | 2023 |
| Dragonflame Candles Ltd | Manufacturing | 2020 |
| Dragons Property Ltd | Real estate | 2024 |
| Drain Inspect UK Ltd | Water & waste | 2023 |
| Drain Quick Ltd | Construction | 2025 |
| Drainscan Limited | Water & waste | 1971 |
| Drake Housing Ltd | Real estate | 2003 |
| Drakehouse Limited | Construction | 2000 |
| Drape House Curtains & Beddings Ltd | Other services | 2026 |
| Drapers Bridge Management Company Limited | Households | 2015 |
| Drapers GUN Centre Limited | Wholesale & retail | 2002 |
| Drapery Management Limited | Construction | 2024 |
| Drapery Property Northampton Limited | Construction | 2020 |
| Dravya Discovery Ltd | Professional & scientific | 2020 |
| Drawing Office Requisites Limited | Manufacturing | 1988 |
| Drawn to Sports Ltd | Manufacturing | 2023 |
| Drawnablank Ltd | Professional & scientific | 2002 |
| Draxsolutions Limited | Hospitality | 2025 |
| Draycott & Sons (Holdings) Limited | Financial services | 2024 |
| Draycott Healthcare Limited | Wholesale & retail | 2025 |
| Draycott Mill Management Company Limited | Real estate | 2002 |
| Draycott Trailer Rentals Ltd | Administrative & support | 2024 |
| Draycotts Properties Ltd | Construction | 2025 |
| Drayman Court Management Ltd | Households | 2021 |
| Drayman Limited | | 1954 |
| Drayton Property Group Limited | Real estate | 2021 |
| DRB Projects Limited | Construction | 2009 |
| DRE Investments Ltd | Other services | 2020 |
| Dream House Solutions Ltd | Real estate | 2020 |
| Dream on! International Limited | Education | 2022 |
| Dream Team Commercial Cleaning Ltd | Administrative & support | 2023 |
| Dream Weddings and Events Ltd | Other services | 2016 |
| Dreamcare+ Ltd | Administrative & support | 2021 |
| Dreamcleanz Limited | Administrative & support | 2018 |
| Dreamcloud Media Limited | Administrative & support | 2016 |
| Dreamers Nest Limited | Hospitality | 2025 |
| Dreamhaute Ltd | Wholesale & retail | 2023 |
| Dreamhouse Property Limited | Real estate | 2026 |
| Dreamland Nursery Ltd | Education | 2025 |
| Dreamnestuk Limited | Construction | 2023 |
| Dreams Carz Ltd | Wholesale & retail | 2025 |
| Dreams Carz' Autocentre&Mot Limited | Wholesale & retail | 2026 |
| Dreamsport 2022 Limited | Wholesale & retail | 2022 |
| Dreamworld Ltd | Wholesale & retail | 2025 |
| Dreamy Desserts Nottingham Ltd | Wholesale & retail | 2025 |
| Dreamz Realty Ltd | Construction | 2023 |
| Dreamzul Limited | Real estate | 2026 |
| Dregan Services Ltd | Professional & scientific | 2019 |
| Dremind Limited | Manufacturing | 1977 |
| Drensmely Limited | Professional & scientific | 2020 |
| DRG Services Ltd | Construction | 2018 |
| Drift Composites Ltd | Manufacturing | 2024 |
| Driftroom Ltd | Wholesale & retail | 2016 |
| Driftwood East Midlands Limited | Real estate | 2025 |
| Driftwood Norfolk Ltd | Construction | 2025 |
| Drillbase Ltd | Wholesale & retail | 2025 |
| Drink Italian Limited | Wholesale & retail | 2014 |
| Drink PRE Limited | Manufacturing | 2026 |
| Drinks Industry Insider Limited | Professional & scientific | 2025 |
| Drinks Solutions UK Limited | Professional & scientific | 2023 |
| Drinkwater Nominees LP | | 2007 |
| Drip Create Ltd | Information & communication | 2026 |
| Dripn Panda Ltd | Wholesale & retail | 2024 |
| Drive Concrete Ltd | Transport & logistics | 2021 |
| Drive Consultancy Limited | Professional & scientific | 2014 |
| Drive Intensive Limited | Education | 2021 |
| Drive Plus Ltd | Education | 2025 |