| S Property Management Limited | Households | 2009 |
| S&A Radia Investments Limited | Financial services | 2018 |
| S&D Mclaren Properties Ltd | Real estate | 2021 |
| S&N JV Ltd | Construction | 2025 |
| S&S Meridian Ltd | Real estate | 2020 |
| S2 Asset Management Limited | Administrative & support | 2008 |
| SA Optical Ltd | Health & social care | 2014 |
| Saaj Limited | Wholesale & retail | 1990 |
| Sabaneh Limited | Real estate | 2016 |
| Sabel Capital Limited | Real estate | 2017 |
| Sable London Ltd | Manufacturing | 2024 |
| Sabr Ventures Ltd | Real estate | 2024 |
| SAC Medical Ltd | Health & social care | 2024 |
| Sach Travel Consultants Ltd | Administrative & support | 2025 |
| Sadaat Express Limited | Hospitality | 2016 |
| Safa Lounge Ltd | Hospitality | 2023 |
| Safa Properties London Limited | Real estate | 2019 |
| Safaan Investments Limited | Real estate | 2018 |
| Safe Field Limited | Real estate | 2008 |
| Safe Ledger Solutions Ltd | Professional & scientific | 2025 |
| Saffon UK Limited | Real estate | 1999 |
| Safiyyamda Limited | Real estate | 2025 |
| Sahamm Limited | Real estate | 2014 |
| Sahay Investments Limited | Real estate | 2025 |
| SAI Health Foods Limited | Wholesale & retail | 2017 |
| SAI Hospitality Limited | Hospitality | 2024 |
| SAI MAA (2026) Ltd | Real estate | 2026 |
| SAI MAA Healthcare Limited | Financial services | 2016 |
| SAI MAA Investment Ltd | Health & social care | 2025 |
| SAI Nutrition Centre Limited | Health & social care | 2005 |
| Saioce Consultancy Ltd | Administrative & support | 2026 |
| Saiproco Limited | Real estate | 2017 |
| Saira Nutrition Limited | Health & social care | 2023 |
| Sairam Tech Solutions Ltd | Information & communication | 2015 |
| Sakin Holdings Ltd | Real estate | 2019 |
| Sakra Limited | Financial services | 2012 |
| Sakurablossom Limited | Hospitality | 2019 |
| Salayfa Ltd | Wholesale & retail | 2017 |
| Salcombe Sea School Ltd | Wholesale & retail | 2021 |
| Salesforce Consultancy Limited | Information & communication | 2019 |
| Salhouse Ltd | Information & communication | 2021 |
| Sali Pharma Ltd | Manufacturing | 2024 |
| Salient Management Consulting Ltd | Information & communication | 2017 |
| Sallywags Grooming & Daycare Limited | Other services | 2024 |
| Sallywags Ltd | Wholesale & retail | 2018 |
| Salutaris Healthcare Limited | Public administration | 2023 |
| SAM Long Independent Marine Services Group Limited | Administrative & support | 2021 |
| Saman & Saman Ltd | Wholesale & retail | 2025 |
| Samim Azimi Ltd | Manufacturing | 2026 |
| Samrat Trading Limited | Wholesale & retail | 2015 |
| Samson Property Ventures Limited | Real estate | 2005 |
| Samson Space International Ltd. | Administrative & support | 1998 |
| SAN Monique Ltd | Real estate | 2021 |
| Sanatana Consultants Ltd | Real estate | 2023 |
| Sanatana D E Global Ltd | Real estate | 2023 |
| Sanatana Developments Ltd | Real estate | 2023 |
| Sanatana Developments MR Ltd | Real estate | 2023 |
| Sandhia Investments Ltd | Real estate | 2023 |
| Sandhurst Court (Northwood) Limited | Construction | 2014 |
| Sandhurst Developments Limited | Construction | 2011 |
| Sandrock Investments Ltd | Real estate | 2016 |
| Sandy Lodge Court (Northwood) Limited | Households | 1990 |
| Sandy Lodge Golf Club Limited | Arts & recreation | 1929 |
| Sane Digital Services Ltd. | Information & communication | 2016 |
| Saneitconsultancy Limited | Information & communication | 2013 |
| Sani Properties Limited | Construction | 2014 |
| Sani Shah Investment Ltd | Real estate | 2023 |
| Sanika Limited | Real estate | 2008 |
| Sanni Associates Limited | Professional & scientific | 2015 |
| Sanni Homes Limited | Real estate | 2019 |
| Santipraxis Ltd | Professional & scientific | 2013 |
| Sapbw Solution Ltd | Information & communication | 2011 |
| Saptek Solutions Limited | Information & communication | 2022 |
| Sara Realty Limited | Real estate | 2020 |
| Sargeants Partnership LLP | | 2019 |
| Sarivaa Limited | Other services | 2015 |
| Sarratt Lodge Limited | Households | 2016 |
| SAS Energy Services Limited | Administrative & support | 2016 |
| Sasa Corporation Limited | Real estate | 2017 |
| Sasa Foods Limited | Hospitality | 2017 |
| Sasa Management Ltd | Real estate | 2017 |
| SAT Housing Limited | Hospitality | 2016 |
| Savay Consultants Limited | Professional & scientific | 2022 |
| Savay Group Limited | Administrative & support | 2025 |
| Savers Supermarket Ltd | Wholesale & retail | 2023 |
| Sayani Properties Ltd | Real estate | 2020 |
| Sayco Care Ltd | Health & social care | 2013 |
| SB Legal Consulting Ltd. | Professional & scientific | 2024 |
| SB45 Limited | Wholesale & retail | 2022 |
| SCA Prop Management Limited | Real estate | 2025 |
| Scalemount Limited | Real estate | 2006 |
| Scan Euro Steel (UK) Limited | Extraterritorial | 1999 |
| Scandal (Club Brand) Ltd | Hospitality | 2017 |
| Schad Property Limited | Real estate | 2020 |
| Schedule 32 Limited | Hospitality | 2004 |
| Schiehallion Consulting Ltd | Information & communication | 2018 |
| Scientia Associates Limited | Professional & scientific | 2023 |
| Scimitar Screen Services Limited | Information & communication | 2014 |
| SD Health Consulting Ltd | Professional & scientific | 2022 |
| Sd&I Ltd | Manufacturing | 2025 |