| MC Building & Roofing Ltd | Construction | 2025 |
| Mcaulay Morgan Rentals Limited | Real estate | 2022 |
| MCC Maroni Limited | Real estate | 2018 |
| Mccombie Construction Ltd. | Construction | 2012 |
| Mccombie Developments Ltd | Construction | 2020 |
| Mccombie Properties Ltd. | Construction | 2017 |
| Mccoy Landscapes Limited | Administrative & support | 2024 |
| Mcdg Developments Ltd | Construction | 2019 |
| Mcdg Properties Ltd | Real estate | 2019 |
| Mcewan Contractors Limited | Agriculture & fishing | 2007 |
| MCG Investment Group Limited | Other services | 2026 |
| Mcgeary Holdings Limited | Financial services | 2013 |
| Mcgill Health Ltd | Wholesale & retail | 2021 |
| Mchiles Consultancy Limited | Education | 2021 |
| MCO Holdings Ltd | Real estate | 2023 |
| MCW Refurbishments Limited | Hospitality | 2025 |
| MDC Property Mgmt Ltd | Real estate | 2026 |
| Mdem Property Limited | Real estate | 2018 |
| MDM Property Ltd | Construction | 2018 |
| MDW (UK) Ltd | Wholesale & retail | 2014 |
| MDW Logistics Ltd | Transport & logistics | 2019 |
| ME Tea Ltd | Wholesale & retail | 2026 |
| Meadowcroft Estate Management Limited | Real estate | 2001 |
| Medburn Limited | Health & social care | 2023 |
| Medhub Ltd | Health & social care | 2022 |
| Mediable Ltd | Information & communication | 2009 |
| MEDIAWALLS2U Ltd | Professional & scientific | 2024 |
| Medica Therapies Ltd | Other services | 2020 |
| Medical Home Care NOW Limited | Health & social care | 2024 |
| MEE Commerce Ltd | Wholesale & retail | 2022 |
| Meerkat Management Ltd | Households | 2026 |
| Melamar Limited | Real estate | 2020 |
| Melville PR Ltd | Professional & scientific | 2012 |
| Menshouldtalk Limited | Health & social care | 2021 |
| Mensor Surveyors Limited | Professional & scientific | 2018 |
| Menus Matter Limited | Hospitality | 2008 |
| Mercia Medicine LLP | | 2022 |
| Mere Construction & Concrete Floors Ltd | Construction | 2022 |
| Mereworth Electronics Limited | Wholesale & retail | 2010 |
| Merryfall Cakes Bakery Limited | Manufacturing | 2023 |
| Metalworks of Cheshire Limited | Manufacturing | 2018 |
| Mezcalitas Ltd | Wholesale & retail | 2024 |
| MFG Group Holdings Limited | Financial services | 2024 |
| MFG Group Limited | Professional & scientific | 1999 |
| Mgks Solutions Ltd | Information & communication | 2022 |
| MGR Property Management Limited | Real estate | 1992 |
| MGT Brands Limited | Wholesale & retail | 2026 |
| Mgturner Ltd | Real estate | 2026 |
| Miantra Inclusive Living Ltd | Hospitality | 2025 |
| MIB Retail Ltd | Wholesale & retail | 2025 |
| Mibrook Engineering Ltd | Professional & scientific | 2011 |
| Mick Cookson Photography Limited | Information & communication | 1996 |
| Mick Hocking Limited | Professional & scientific | 2019 |
| Micro BIO Consultants Limited | Professional & scientific | 2015 |
| Microhelp Limited | Information & communication | 1984 |
| MID Cheshire Anaesthetic Services Limited | Health & social care | 2023 |
| MID Cheshire Community Rail Partnership CIC | Transport & logistics | 2020 |
| MID Cheshire Electrical Limited | Manufacturing | 2016 |
| MID Cheshire Roofing Ltd | Construction | 2025 |
| MID Cheshire Solutions Limited | Transport & logistics | 2017 |
| MID Cheshire Window Cleaning Limited | Administrative & support | 2019 |
| Mid-Cheshire Accountants Ltd | Professional & scientific | 2011 |
| Mid-Cheshire Fixing Products Limited | Wholesale & retail | 2000 |
| Middleton Wissett Risk Consulting Limited | Professional & scientific | 2014 |
| Midnight Oasis Limited | Information & communication | 2003 |
| Mike Chadwick Media & Managment Ltd | Other services | 2015 |
| Mike Harper Consulting Ltd | Professional & scientific | 2018 |
| Mike Leather Ltd | Wholesale & retail | 2024 |
| Mike Thompson Electrical Limited | Construction | 1987 |
| Miles Better Holidays Ltd | Administrative & support | 2020 |
| Mill Lane Garage Kingsley Limited | Wholesale & retail | 2013 |
| Millington Hadrian Group Limited | Professional & scientific | 2020 |
| Miloski Limited | Professional & scientific | 2012 |
| Miltec Digital Limited | Information & communication | 2003 |
| Mincher OPS Group Limited | Information & communication | 2026 |
| Mind Body Balance Academy CIC | Arts & recreation | 2024 |
| Mind HOW YOU Thrive Ltd | Education | 2025 |
| Minerva Holdings (Cheshire) Limited | Financial services | 2024 |
| Minivent Company Limited(The) | Professional & scientific | 1967 |
| Mint Commercial and Healthcare Ltd | Administrative & support | 2016 |
| Mint Creative Strategy Ltd | Professional & scientific | 2025 |
| Mint Ventures Ltd | Wholesale & retail | 2019 |
| Mirca Properties Limited | Construction | 2019 |
| Miri Consulting Limited | Professional & scientific | 2020 |
| Mirkwood Associates Ltd | Administrative & support | 2024 |
| Mirwell Homes Ltd | Extraterritorial | 2006 |
| MIS Active Finance Limited | Information & communication | 2022 |
| MIS Blue Light Services Group Limited | Information & communication | 2025 |
| MIS Emergency Systems Limited | Information & communication | 2001 |
| MIS Group Holdings Limited | Information & communication | 2019 |
| MJ Flooring and SON Ltd | Wholesale & retail | 2025 |
| MJ Fowler Limited | Professional & scientific | 2025 |
| MJB Hospitality Ltd | Hospitality | 2010 |
| MJM Bespoke Build Limited | Construction | 2019 |
| MK 3 Consultancy Limited | Information & communication | 2015 |
| Mlct Ltd | Information & communication | 2008 |
| MLH Engineering Inspection Limited | Administrative & support | 2007 |
| MLJ Finance Limited | Financial services | 2025 |
| Mlpharms Ltd | Financial services | 2010 |
| MLV Consultancy Limited | Professional & scientific | 2014 |