| Every Think in One Shop Ltd | Wholesale & retail | 2025 |
| Everybody Counts (Northampton) Limited | Health & social care | 2024 |
| Everyclient Limited | Professional & scientific | 2004 |
| Everyday English Ltd | Education | 2016 |
| Everyone Elite C.I.C. | Education | 2024 |
| Everything IS Beautiful Ltd | Information & communication | 2025 |
| Eviee Technologies Limited | Information & communication | 2018 |
| Evin Kebab Limited | Hospitality | 2016 |
| Evnex Limited | Wholesale & retail | 2018 |
| EVO Personnel Holdings Limited | Financial services | 2025 |
| EVO Personnel Limited | Administrative & support | 2021 |
| Evolucija C.I.C. | Other services | 2021 |
| Evolutax Limited | Professional & scientific | 2024 |
| Evolution Capital (UK) Limited | Financial services | 2010 |
| Evolution Engineers Ltd | Professional & scientific | 2012 |
| Evolution Solution Services Limited | Financial services | 2025 |
| Evolution Transport (Northants) Limited | Transport & logistics | 2010 |
| Evolve Advice Ltd | Education | 2017 |
| Evolve Automotive Consultancy Ltd | Professional & scientific | 2025 |
| Evolve Cars Northampton Ltd | Transport & logistics | 2023 |
| Evolve Creative Consulting Ltd | Other services | 2004 |
| Evolve Electrical Installations Ltd | Construction | 2019 |
| Evolve Healthcare Products Limited | Wholesale & retail | 2014 |
| Evolve Hospitality Recruitment Holdings Limited | Administrative & support | 2023 |
| Evolve Hospitality Recruitment Ltd | Administrative & support | 2013 |
| Evolve Supported Living Ltd | Hospitality | 2024 |
| Evolve Your Future Limited | Education | 2007 |
| Evosha Holdings Ltd | Financial services | 2018 |
| EVZ Electrical Limited | Manufacturing | 2024 |
| EW Events Ltd | Administrative & support | 2025 |
| EW Floral Limited | Wholesale & retail | 2025 |
| EWA Trans Ltd | Transport & logistics | 2013 |
| Ewest Healthcare Limited | Health & social care | 2012 |
| Ewiz Logistics Ltd | Administrative & support | 2021 |
| EWM FP Ltd | Professional & scientific | 2021 |
| EX Transport Ltd | Transport & logistics | 2018 |
| EX Valeting Services Ltd | Other services | 2018 |
| Excalibur Furniture Ltd | Wholesale & retail | 1998 |
| Excalibur Real Estate Ltd | Real estate | 2014 |
| Exceed Support Services Ltd | Health & social care | 2017 |
| Excel 24 Limited | Information & communication | 2013 |
| Excel Body Repairs Limited | Administrative & support | 2002 |
| Excel Corporation Ltd | Financial services | 2025 |
| Excel Drainage Ltd | Water & waste | 2020 |
| Excel Environmental Ltd | Water & waste | 2026 |
| Excel Medical Ltd | Professional & scientific | 2023 |
| Excel Properties (Northampton) Limited | Real estate | 2008 |
| Excel Roofing Solutions Ltd | Construction | 2016 |
| Excel TDM Ltd | Health & social care | 2021 |
| Excelcium Consulting Limited | Professional & scientific | 2014 |
| Excelerate Packaging Services Ltd | Manufacturing | 2025 |
| Excellent Catering Ltd | Hospitality | 2018 |
| Excellent Source Catering Ltd | Manufacturing | 2024 |
| EXCELR8IN Ltd | Information & communication | 2020 |
| Excelserve Electrical Contractors Ltd | Construction | 2021 |
| Exceptional Trailer Rental Limited | Administrative & support | 2020 |
| Exchange Group NN Limited | Hospitality | 2025 |
| Exclusive Logistiq Ltd | Transport & logistics | 2018 |
| Exclusive Ventures & Co Ltd | Hospitality | 2025 |
| Exeat Leisure Limited | Financial services | 2014 |
| Exec Grooming Ltd | Other services | 2020 |
| Exib Limited | Construction | 2001 |
| Exitref Ltd | Wholesale & retail | 2025 |
| EXL Pharmacy Limited | Health & social care | 2009 |
| Exodus Law Ltd | Professional & scientific | 2014 |
| Exodus Luxe Ltd | Wholesale & retail | 2025 |
| Exotic Kudos Ltd | Wholesale & retail | 2019 |
| Experia Limited | Information & communication | 1998 |
| Experience Design Consultants Ltd | Information & communication | 2016 |
| Experience Healthcare Professionals Ltd | Public administration | 2018 |
| Expert Barbers Northampton Ltd | Other services | 2025 |
| Expert Carpet Cleaning Services Ltd | Extraterritorial | 2025 |
| Expert Clearcoat Correction Ltd | Wholesale & retail | 2026 |
| Expert Image Photography Limited | Other services | 2016 |
| Expert Tyres Limited | Wholesale & retail | 2015 |
| Expert UK Cleaning Ltd | Administrative & support | 2019 |
| Exploratory Consultants Limited | Professional & scientific | 2025 |
| Explore Chocolate Ltd | Manufacturing | 2020 |
| Expodya E-Commerce Ltd | Wholesale & retail | 2022 |
| Export-Tech Limited | Transport & logistics | 2005 |
| Exporto England Ltd | Transport & logistics | 2022 |
| Express Barbers Limited | Other services | 2014 |
| Express Building Ltd | Construction | 2016 |
| Express Composite Solutions Ltd | Manufacturing | 2012 |
| Express Containers Ltd | Transport & logistics | 2008 |
| Express Ductwork Services Limited | Construction | 1997 |
| Express Falcon Ltd | Transport & logistics | 2016 |
| Express Ironing Services Limited | Other services | 2025 |
| Express Lubricants Limited | | 1989 |
| Express Recovery Solutions Ltd | Transport & logistics | 2021 |
| Express Store Northampton Ltd | Wholesale & retail | 2026 |
| Express Tanning & Beauty Ltd | Other services | 2011 |
| Express Van Ltd | Transport & logistics | 2023 |
| Express-Sameday Ltd | Transport & logistics | 2025 |
| Expression Music School Ltd | Information & communication | 2022 |
| Expressroute Courier & Logistics Ltd | Transport & logistics | 2025 |
| Exquisite Enhancements Ltd | Other services | 2023 |
| Exquisite Indian Cuisine Limited | Hospitality | 2011 |
| Exrat Limited | Hospitality | 2013 |
| Exrat Operations Limited | Hospitality | 2014 |