| Strategzilla Ltd | Information & communication | 2022 |
| Stratford Garage Limited | Manufacturing | 2016 |
| Stratford Property (Investments) Limited | Real estate | 1999 |
| Stratford Property Services Limited | Real estate | 1999 |
| Stratford Special Projects Ltd | Professional & scientific | 2024 |
| Stratfords Fashions Limited | Wholesale & retail | 1996 |
| Stratigen Health & Life Sciences Ltd | Professional & scientific | 2026 |
| Strawmag Ltd | Manufacturing | 2019 |
| Streamline Studios Ltd | Administrative & support | 2019 |
| Street Food Club Limited | Hospitality | 2017 |
| Street Level Music Group Limited | Arts & recreation | 2020 |
| Street Philosophy Ltd | Wholesale & retail | 2021 |
| Streets Property Investments Limited | Real estate | 2025 |
| Streetwise Management Limited | Other services | 2012 |
| Strength LAB Gym Ltd | Education | 2021 |
| Strength Within 01 Ltd | Wholesale & retail | 2025 |
| Strength Within by KT Limited | Arts & recreation | 2025 |
| Stretch Vision Ltd | Construction | 2022 |
| Stribbons Ltd | Manufacturing | 2011 |
| Strictly Podiatry Ltd | Health & social care | 2024 |
| Stridden Limited | Administrative & support | 2025 |
| Stride Ahead Ltd | Education | 2024 |
| Strides Group Ltd | Other services | 2021 |
| Stringer-Bourne Limited | Professional & scientific | 2020 |
| Strive (Overseas) Limited | Health & social care | 1963 |
| Strivo United Ltd | Arts & recreation | 2025 |
| Strm Solutions Ltd | Transport & logistics | 2025 |
| Strong Anderson Ltd | Professional & scientific | 2026 |
| Strong Furniture Ltd | Manufacturing | 2023 |
| Strong Plastering Ltd | Construction | 2026 |
| Stronghold Trading Group Ltd. | Professional & scientific | 2003 |
| Strongtower Lettings Ltd | Real estate | 2023 |
| Stroy Construction Ltd | Construction | 2020 |
| Structurapro Ltd | Construction | 2023 |
| Strydden Ltd | Administrative & support | 2026 |
| Sttebs Education Limited | Education | 2024 |
| Stuart Banks Engineering Limited | Professional & scientific | 2003 |
| Stuart House Investments Limited | Construction | 2024 |
| Stuart Innovations Limited | Professional & scientific | 2024 |
| Stuart Investment Holdings Limited | Construction | 2024 |
| Stuart Keeves Ltd | Transport & logistics | 2021 |
| Stuart M Johnson Limited | Administrative & support | 2008 |
| Student Chat Limited | Education | 2018 |
| Student Homes Limited | Real estate | 2010 |
| Student Moral Support Ltd | Education | 2019 |
| Studentdot Limited | Information & communication | 2023 |
| Studfast Stud Welding Limited | Manufacturing | 1988 |
| Studio 53C Limited | Other services | 2020 |
| Studio C Dance Ltd | Education | 2025 |
| Studio DC Ltd | Professional & scientific | 2015 |
| Studio Directory Ltd | Professional & scientific | 2026 |
| Studio Laurie Ltd | Information & communication | 2026 |
| Studio One Media Centre Limited | Manufacturing | 2003 |
| Studio Perkins Ltd | Professional & scientific | 2024 |
| Studio Salmon Ltd | Information & communication | 2026 |
| Studio Seventeen Pilates Limited | Arts & recreation | 2025 |
| STUDIO1 Classic Ltd | Other services | 2021 |
| Studiome Interiors Limited | Professional & scientific | 2023 |
| Studios NN1 Ltd | Real estate | 2025 |
| Study Smart Academy Ltd | Administrative & support | 2024 |
| Study Tech Limited | Information & communication | 2023 |
| STUFF4YOU Ltd | Wholesale & retail | 2024 |
| Stunited Community Interest Company | Information & communication | 2019 |
| Sturins Transport Ltd | Transport & logistics | 2017 |
| Style and Fashion Events Limited | Hospitality | 2022 |
| Style Cheat Ltd | Wholesale & retail | 2018 |
| Style Empire Ltd | Manufacturing | 2016 |
| Style Hospitality Limited | Hospitality | 2010 |
| Styleglaze Installations Limited | Construction | 2009 |
| Styler LAB Limited | Wholesale & retail | 2026 |
| Styler MX Northampton Limited | Wholesale & retail | 2020 |
| Stylez Limited | Other services | 2025 |
| Stylus Collections Ltd | Wholesale & retail | 2023 |
| Stymon Ltd | Real estate | 2021 |
| SU3 Wfsc Ltd | Real estate | 2019 |
| SUB Blue Developments Ltd | Real estate | 2022 |
| SUB Blue Homes Ltd | Real estate | 2022 |
| SUB Blue Ltd | Construction | 2014 |
| Subbie Ltd | Information & communication | 2022 |
| Sublime Media Limited | Information & communication | 2004 |
| Subs Brickwork Limited | Construction | 2020 |
| Subs Construction Limited | Construction | 2019 |
| Subs Resourcing Ltd | Construction | 2018 |
| Substantia Portfolio Limited | Real estate | 2014 |
| Subway GT Billing Ltd | Hospitality | 2022 |
| Success Plus Limited | Information & communication | 2011 |
| Success Point Education Ltd | Education | 2025 |
| Succour Health Practitioners Ltd | Public administration | 2023 |
| Suco Medical Limited | Health & social care | 2025 |
| SUE Cardy Ltd | Other services | 2021 |
| SUE West 1 Limited | Real estate | 2019 |
| SUE West 2 Limited | Real estate | 2019 |
| Sugar Factory Ltd | Wholesale & retail | 2021 |
| Sugar Riot Ltd | Manufacturing | 2026 |
| Suit of Sins Trans Ltd | Transport & logistics | 2025 |
| Sujo Property Ltd | Real estate | 2021 |
| Sukuya Limited | Hospitality | 2014 |
| Sultan's Kitchen 2023 Ltd | Hospitality | 2023 |
| SUM Answers Limited | Professional & scientific | 2005 |
| Summer Furniture Ltd | Wholesale & retail | 2025 |