| Sharper Fibre Ltd | Administrative & support | 2023 |
| Sharper Financial Planning Ltd | Financial services | 2024 |
| Sharpmark Solutions LLP | | 2007 |
| Shaw Advisory & Capital Limited | Professional & scientific | 2021 |
| Shaw and Hunter (Hunting and Fishing Worldwide) Ltd | Agriculture & fishing | 2024 |
| Shawarma Grill Northampton Ltd | Hospitality | 2021 |
| Shawburg Ltd | Hospitality | 2024 |
| Shawre Ltd | Wholesale & retail | 2021 |
| Shawry Services Ltd. | Construction | 2022 |
| Shayneruth Limited | Transport & logistics | 2025 |
| SHC Installation Ltd | Wholesale & retail | 2023 |
| Sheaf Close Catering Limited | Hospitality | 2023 |
| Shears Way Ltd | Wholesale & retail | 2025 |
| Shed Properties Ltd | Real estate | 2021 |
| Shedding Light Ltd | Professional & scientific | 2016 |
| Shedirey International Limited | Wholesale & retail | 2024 |
| Sheena Davison & Associates Limited | Health & social care | 2024 |
| Sheer Sports Limited | Arts & recreation | 2008 |
| Shefa Trading Limited | Wholesale & retail | 2024 |
| Sheffield 3 Limited | Professional & scientific | 2019 |
| Sheffield Wednesday Football Club Limited | Arts & recreation | 1990 |
| Shefford Developments Limited | Construction | 2016 |
| Shehnaz Limited | Health & social care | 2022 |
| Sheikh Industries Ltd | Information & communication | 2020 |
| Sheilites Ltd | Health & social care | 2022 |
| Sheinman Opticians Limited | Health & social care | 2007 |
| Shekigrill Ltd | Hospitality | 2025 |
| Sheldon Property Ltd | Real estate | 2021 |
| Sheldon Research Ltd | Information & communication | 2022 |
| Shelf Life Shop Ltd | Wholesale & retail | 2025 |
| Shell Agri Limited | Wholesale & retail | 2020 |
| Shell Marketing Limited | Professional & scientific | 2011 |
| Shellas Limited | Health & social care | 2016 |
| Shelley's Catering Services Ltd | Other services | 2018 |
| Shellplant LLP | | 2025 |
| Shelly K Limited | Health & social care | 2012 |
| Shellyk Clinic Ltd | Health & social care | 2021 |
| Shelton Electrical Services Limited | Construction | 2006 |
| Shema Computer Services Ltd. | Transport & logistics | 2008 |
| Shenka Ltd | Water & waste | 2023 |
| Shenly Limited | Other services | 2017 |
| Shep Holdings Ltd | Financial services | 2024 |
| Shepherd Decorating Ltd | Construction | 2016 |
| Sheppard CMS Ltd | Professional & scientific | 2025 |
| Sheppards Close NP Management Co (2013 ) Ltd | Households | 2013 |
| Sheppards Court (RTM) Management Company Ltd | Households | 2006 |
| Sheraton & Sons Property Services Ltd | Construction | 2011 |
| Sherbourne Recruitment Associates Limited | Administrative & support | 2018 |
| Shergill Logistics Limited | Transport & logistics | 2018 |
| Sheridan & Jephcott Limited | Construction | 2000 |
| Sherman Transport Limited | Transport & logistics | 2012 |
| Shermarsh Ltd | Real estate | 2025 |
| Sherpa MT Limited | Health & social care | 2025 |
| Sherry Design Limited | Administrative & support | 1996 |
| Sherwood Maintenance Limited | Administrative & support | 2024 |
| Shetty Medical Services Limited | Health & social care | 2024 |
| Shezza Ltd | Health & social care | 2018 |
| SHF Homes Ltd | Construction | 2024 |
| SHF Ltd | Construction | 2021 |
| Shgh IS Consultancy Ltd | Information & communication | 2013 |
| Shhstreetwear Limited | Wholesale & retail | 2019 |
| SHI Miah Properties Ltd | Households | 2026 |
| Shialoh Services Limited | Health & social care | 2014 |
| Shiel Developments Ltd | Construction | 2015 |
| Shield NN Ltd | Public administration | 2022 |
| Shield Transport Ltd | Transport & logistics | 2025 |
| Shields Fire Doors Ltd | Construction | 2025 |
| Shift N Fit Limited | Other services | 2026 |
| Shillingstone Fields Management Limited | Real estate | 2026 |
| Shine Development Concept CIC | Health & social care | 2012 |
| Shine Marketing Limited | Professional & scientific | 2026 |
| Shine Pro Cleaning Ltd | Administrative & support | 2024 |
| Shine With P Ltd | Administrative & support | 2025 |
| Shining Lights Enterprise C.I.C. | Other services | 2024 |
| Shinobi Consulting Ltd | Professional & scientific | 2025 |
| Shinobi Investments Limited | Real estate | 2023 |
| Shinwari M Limited | Hospitality | 2023 |
| Shinwari M-Food Limited | Hospitality | 2026 |
| Shipping Made Easy Limited | Transport & logistics | 2016 |
| Shipston Road Alderminster Management Company Limited | Extraterritorial | 2016 |
| Shirdi SAI RAM Properties Ltd | Real estate | 2021 |
| Shire Aggregate Recycling Ltd | Water & waste | 2024 |
| Shire Alliance Commercial Ltd | Administrative & support | 2022 |
| Shire Alliance Domestic Limited | Administrative & support | 2018 |
| Shire Alliance Group Ltd | Administrative & support | 2022 |
| Shire Mobility EOT Trustees Limited | Administrative & support | 2023 |
| Shire Mobility Limited | Wholesale & retail | 2001 |
| Shires Artificial Lawn Care Limited | Administrative & support | 2023 |
| Shirley Street Properties Limited | Real estate | 2025 |
| Shivaay Imports Ltd | Wholesale & retail | 2024 |
| Shivalry Ltd | Professional & scientific | 2023 |
| Shive Enterprise Limited | Hospitality | 2023 |
| Shoar Design Limited | Professional & scientific | 2015 |
| Shoe Army Clothing Ltd | Wholesale & retail | 2026 |
| Shoe Merchants House Management Company Limited | Real estate | 2003 |
| Shoebarn Developments Limited | Real estate | 2024 |
| Shoebridge Engineers Ltd | Manufacturing | 2020 |
| Shoebridge Holdings Ltd | Financial services | 2021 |
| Shoebridge Investments Ltd | Financial services | 2021 |
| Shoetown Coffee Ltd | Wholesale & retail | 2021 |