| Acarrr Ltd | Construction | 2025 |
| Accessacity Ltd | Information & communication | 2025 |
| Accident Hotline Limited | Financial services | 2005 |
| Accsentient Limited | Information & communication | 2022 |
| ACD Hospitality Ltd | Hospitality | 2024 |
| ACG Homes Ltd | Real estate | 2024 |
| ACG Support Ltd | Health & social care | 2024 |
| ACG Topco Ltd | Financial services | 2024 |
| Acorns (North Tyneside) | Health & social care | 2014 |
| Acre Design NE Ltd | Professional & scientific | 2017 |
| Activate Health Ltd | Arts & recreation | 2025 |
| Activate Physiotherapy Limited | Health & social care | 2013 |
| Active Care and Development Ltd | Education | 2022 |
| Active Leisure & Entertainment Limited | Administrative & support | 2024 |
| Activities Abroad Limited | Administrative & support | 2004 |
| ACW Property Management Company Limited | Households | 2017 |
| AD & G Investments Ltd | Real estate | 2025 |
| AD Naturum Ltd | Professional & scientific | 2026 |
| ADC Wind-Tech Ltd | Construction | 2025 |
| Adderley Associates Ltd | Professional & scientific | 2022 |
| Adlek Limited | Construction | 1999 |
| Adpg Property Ltd | Real estate | 2025 |
| Advance Fire & Security Systems Limited | Real estate | 2022 |
| ADVANCE365 Ltd | Wholesale & retail | 2017 |
| Advanced Interior Solutions North East Limited | Professional & scientific | 2010 |
| Aegeus Limited | Professional & scientific | 2008 |
| Aeirtec Ltd | Professional & scientific | 2003 |
| Aerial Beats Ltd | Education | 2026 |
| Aetherys Ltd | Information & communication | 2025 |
| Afass Limited | Administrative & support | 2013 |
| Afortiori Development Ltd | Professional & scientific | 2017 |
| Agamed Mental Health Ltd | Health & social care | 2019 |
| AGE UK Newcastle and North Tyneside | Health & social care | 1983 |
| AGE UK Newcastle Limited | Other services | 2021 |
| AGE UK North of Tyne Ltd | Other services | 2019 |
| AGE UK NT Corporate Support Services Ltd | Administrative & support | 2022 |
| AHG 25 Ltd | Hospitality | 2025 |
| AHG Fish Quay Ltd | Hospitality | 2025 |
| AHL Industrial Pipework Specialists Ltd | Other services | 1989 |
| AI and Management Qualifications Body Limited | Education | 2025 |
| AI Technology Studios UK Limited | Information & communication | 2025 |
| Aiantas Limited | Other services | 2020 |
| Aikmanandson Ltd | Wholesale & retail | 2026 |
| Aiko Roof Bars Limited | Manufacturing | 2024 |
| Air Conditioning Maintenance Services (U.K.) Ltd | Other services | 2003 |
| Airsoft Draws Ltd | Wholesale & retail | 2026 |
| Airwordy Ltd | Information & communication | 2021 |
| AIS Training Limited | Education | 2023 |
| AJ Cars NE Ltd | Wholesale & retail | 2025 |
| AJ Wylde Consulting Ltd | Professional & scientific | 2025 |
| AJA Engineering Limited | Professional & scientific | 2017 |
| AJB Chiropractic Limited | Health & social care | 2017 |
| Ajlm Services Ltd | Construction | 2025 |
| Ak-Design Limited | Professional & scientific | 2007 |
| Akcreative Ltd | Wholesale & retail | 2023 |
| AKG Science Support Limited | Extraterritorial | 2017 |
| AKM Medical Ltd | Health & social care | 2025 |
| AKP Electrical Limited | Construction | 2020 |
| AL Coastal Properties Limited | Real estate | 2025 |
| Alan Carr Jaguar Services Ltd | Wholesale & retail | 2026 |
| Alan Dennett Financial Services Limited | Financial services | 2012 |
| Alastair Woodruff Ltd | Professional & scientific | 2007 |
| Albatross Golf Holidays & Events Ltd | Administrative & support | 2020 |
| Alcaso Properties Ltd | Real estate | 2016 |
| Alcaso Properties Newcastle Limited | Real estate | 2022 |
| Alcaso Services Ltd | Professional & scientific | 2022 |
| Alegeo Ltd | Professional & scientific | 2025 |
| Alethoscope Media Ltd | Arts & recreation | 2018 |
| Alex Barber Ltd | Other services | 2022 |
| Alexander Legal Services Limited | Professional & scientific | 2019 |
| Algas Medical Installations (North East) Ltd | Construction | 2020 |
| ALL About the Bees Limited | Wholesale & retail | 2019 |
| ALL Stars Nursery Newcastle Ltd | Education | 2012 |
| Allen Baldwin Coatings Ltd | Construction | 2026 |
| Alliance JIU Jitsu Newcastle Limited | Education | 2026 |
| Allstarsgroup LLP | | 2016 |
| Alma Dental Limited | Health & social care | 2019 |
| Almighty / Street Gang Limited | Arts & recreation | 2025 |
| Aloe Education Ltd | Education | 2026 |
| Altevo Energy Ltd | Professional & scientific | 2024 |
| Alva Advisory Ltd | Professional & scientific | 2021 |
| Alvagate Limited | Real estate | 2025 |
| AM Automotive Group Ltd | Wholesale & retail | 2025 |
| AM Comms Network Ltd | Information & communication | 2020 |
| AM Performance Cars Ltd. | Wholesale & retail | 2014 |
| AM Safety Support Ltd | Professional & scientific | 2020 |
| AM Vocal Studio Ltd | Education | 2025 |
| AM Voltage Ltd | Construction | 2026 |
| Amakhala Limited | Professional & scientific | 2005 |
| Americana Blues Festival Limited | Arts & recreation | 2024 |
| Amethyst Independent Financial Advisers LLP | | 2014 |
| AMP! Advisory Ltd | Professional & scientific | 2023 |
| Amron Properties Limited | Real estate | 2009 |
| AMS Welding & Fabrication Ltd | Manufacturing | 2024 |
| AMW Tech Services Ltd | Construction | 2024 |
| AMY Harrison Limited | Professional & scientific | 2018 |
| Ananthaneni Global Services Limited | Information & communication | 2022 |
| Andco Ltd | Information & communication | 2024 |
| Andrew Stobbs Civil Engineering Ltd | Construction | 2021 |
| Andrew Swan Law Limited | Professional & scientific | 2022 |