| Polypearl Limited | Construction | 1985 |
| Positive Impact Communications & Training Limited | Professional & scientific | 2002 |
| Positive Jess Limited | Other services | 2023 |
| Quantumleap Management Systems Ltd | Professional & scientific | 2005 |
| Queensway Engineering (Scunthorpe) Limited | Manufacturing | 1970 |
| R J Coleman (Electrical) Limited | Construction | 2002 |
| R.Hall Aluminium Welding Ltd | Transport & logistics | 2002 |
| R.J.P. Marine Limited | Real estate | 1994 |
| Rapideffort Limited | Hospitality | 1996 |
| Reitanlagen-Stiller (UK) Limited | Wholesale & retail | 2005 |
| Richard Mason Limited | Construction | 2005 |
| Rickmere Limited | Professional & scientific | 1984 |
| River Street Limited | Real estate | 2007 |
| Rocal Insulating Panels Ltd. | Manufacturing | 1993 |
| Rustik Events Ltd | Arts & recreation | 2026 |
| Rustik Kitchen Ltd | Hospitality | 2025 |
| S.G.D. Scaffolding Ltd | Construction | 2001 |
| S.M. Goodchild Limited | Manufacturing | 1973 |
| Scunthorpe Golf Club Limited(The) | Real estate | 1936 |
| Sentex Trading Limited | Manufacturing | 2002 |
| Shamrock Consulting Ltd | Administrative & support | 2019 |
| Shining Little Stars Limited | Education | 2003 |
| Shucksmith Accountants (Brigg) Limited | Professional & scientific | 2002 |
| Simon Group Pension Fund Limited | Financial services | 1999 |
| Simply Angelic Ltd | Administrative & support | 2003 |
| Smith & Walker (Optometrists) Limited | Health & social care | 1969 |
| Solid Structures Limited | Construction | 2004 |
| South Ferriby Marina Limited | Arts & recreation | 2006 |
| Steeper Physical Therapy Services Limited | Health & social care | 2002 |
| Subsaturn Limited | Professional & scientific | 1997 |
| T W S Facias Limited | Water & waste | 2001 |
| T. Dobson Limited | Construction | 1997 |
| T.G. Sowerby Developments Limited | Construction | 1980 |
| Tebway Limited | Construction | 1983 |
| Technica Measurement Limited | Professional & scientific | 2024 |
| THE China Project Management Services Limited | Professional & scientific | 2005 |
| THE Crosby Community Association | Administrative & support | 2004 |
| THE Willows Beauty Salon Limited | Other services | 2002 |
| Thomas Bell & Sons Limited | Wholesale & retail | 1976 |
| Total Steel Solutions Limited | Professional & scientific | 2003 |
| Tower Construction Associates Limited | Construction | 2004 |
| Toyink Enterprise Ltd | Administrative & support | 2016 |
| Trade East (Elsham) Limited | Wholesale & retail | 2008 |
| Truecast Limited | Manufacturing | 2006 |
| TVT Investments Limited | Real estate | 2005 |
| W J Betts Ltd | Construction | 2002 |
| W. Graham & Sons Limited | Real estate | 1964 |
| Wakenhill Ltd | Wholesale & retail | 2003 |
| Walkers Construction Limited | Construction | 1976 |
| Walt's Travel Limited | Information & communication | 2001 |
| Water Margin (Barton) Limited | Extraterritorial | 2003 |
| WFT Developments Limited | Construction | 2005 |
| Woodcombe Developments Limited | Construction | 2005 |
| Wraith Joinery Limited | Manufacturing | 1997 |
| X B G Scunthorpe Limited | Construction | 2004 |
| Yxmmn Ltd | Wholesale & retail | 2026 |