| Selected Beauty Products Limited | Wholesale & retail | 2024 |
| SG Sports and Entertainment Services Limited | Professional & scientific | 2020 |
| Shabeel Shabeel Ltd | Information & communication | 2021 |
| Shackleton Private Finance Ltd | Administrative & support | 2026 |
| Shah Sales Limited | Wholesale & retail | 2021 |
| Shakoor Capital | Financial services | 1998 |
| Shakoor Heritage | Financial services | 2026 |
| Shams Properties Limited | Real estate | 2016 |
| Sharez Holdings Ltd | Real estate | 2024 |
| Sharknation Ltd | Information & communication | 2021 |
| Sharplink Limited | Real estate | 1994 |
| Shenley Homes Ltd | Construction | 2022 |
| Shilpa Shah Consultancy Limited | Professional & scientific | 2023 |
| Shina Investments Limited | Real estate | 2021 |
| Shivron Support Ltd | Health & social care | 2024 |
| Shree Kunj Bihari Temple Vrindavan (UK) | Other services | 2025 |
| Shrewsbury Mews Limited | Households | 2012 |
| Shri Hari Saamarth Minerals Resources Consultancy Ltd | Professional & scientific | 2010 |
| Shri Hari Saamrath Holdings Ltd | Financial services | 2025 |
| Shri Sugarcane Juice and Ice Gola Ltd | Hospitality | 2020 |
| Sighthound Change Coop Ltd | Professional & scientific | 2024 |
| Silver EYE Productions Limited | Information & communication | 2009 |
| Silversands Mediacity Ltd | Real estate | 2016 |
| Sindh Community UK Ltd | Health & social care | 2016 |
| SIR Double Jack Investments Ltd | Real estate | 2023 |
| Sira Cash & Carry Hayes Ltd | Hospitality | 2018 |
| SKV Global Ltd | Hospitality | 2020 |
| SKV Renewables Ltd | Construction | 2004 |
| Slocombe Consultancy Ltd | Administrative & support | 2019 |
| Smart Capital Partners LLP | | 2025 |
| Sngs Property Ltd | Real estate | 2022 |
| SNN Healthcare Services Limited | Health & social care | 2026 |
| SO What NOW Limited | | 1993 |
| Solara Estates Limited | Construction | 2026 |
| South Indian Vision Limited | Hospitality | 2019 |
| Southern Counties Real Estate Company Limited | Real estate | 2014 |
| Souto Properties Limited | Real estate | 2005 |
| Spa Corporation Limited | Real estate | 2018 |
| Sparkmint Ltd | Wholesale & retail | 2024 |
| Sparrow Cleaning, Masticking and Maintenance Ltd | Administrative & support | 2015 |
| Speedocash Limited | Professional & scientific | 2012 |
| Spencer Whittle & Co Ltd | Wholesale & retail | 2000 |
| Sprite Communications Limited | Professional & scientific | 2010 |
| Squareline Roofing Specialist Ltd | Construction | 2023 |
| Srivari Diagnostic Solutions Ltd | Health & social care | 2025 |
| SS DOC Ltd | Health & social care | 2021 |
| ST Temptation Ltd | Hospitality | 2023 |
| Stackflow Technologies UK Ltd | Information & communication | 2020 |
| Star Smiles Aligners Limited | Other services | 2022 |
| Stat Marine Limited | Professional & scientific | 1993 |
| Sugar Village Ltd | Manufacturing | 2023 |
| Sun Accessories Ltd | Wholesale & retail | 2015 |
| Superb Const Ltd | Construction | 2012 |
| Svc-Uk Ltd | Construction | 2021 |
| Svengali Productions Limited | Other services | 2002 |
| Swarntech Limited | Administrative & support | 2025 |
| T & a Building Contractors Limited | Construction | 2015 |
| T&M Homes Ltd | Real estate | 2024 |
| T&U Retail Limited | Wholesale & retail | 2022 |
| TAS Foods Edgware Ltd | Hospitality | 2023 |
| TAS Foods Enfield Limited | Hospitality | 2023 |
| Tayzaar Ltd | Real estate | 2025 |
| Tecunited Investment Limited | Construction | 2022 |
| Telecom Facilities Servicing Advising & Engineering L.P. | | 2019 |
| TGW Compaction Services Limited | Other services | 2012 |
| Thai 4U Limited | Hospitality | 2012 |
| Thames Maintenance Limited | Other services | 2003 |
| Thanam Express Ltd | Wholesale & retail | 2021 |
| THE Boltons Management Company Limited | Households | 2003 |
| THE Ducks Hill Real Estate Company Limited | Real estate | 2018 |
| THE Fairways Healthy Concept Limited | Real estate | 2002 |
| THE Media Haus Ltd | Professional & scientific | 2025 |
| THE Oaks Creche and Pre-School MMC Ltd | Education | 2013 |
| Thermo Consult Limited | Administrative & support | 1993 |
| Thirty Abbey Road Limited | Households | 1994 |
| Thrive Fitness Worldwide Limited | Other services | 2023 |
| Thynknu Limited | Health & social care | 2021 |
| Tidex Finance Corporation Limited | Administrative & support | 1982 |
| Tidy Homes Limited | Construction | 1984 |
| Timeless Realty Limited | Real estate | 2024 |
| Timilsina Properties Limited | Real estate | 2024 |
| Tmat.Io Ltd | Information & communication | 2021 |
| Total Accountancy Solutions Limited | Professional & scientific | 2016 |
| Tower Holding Group Ltd | Financial services | 2018 |
| Tower Property Investments Ltd | Real estate | 2018 |
| Tower Repairs & Maintenance Ltd | Construction | 2018 |
| Trea Consultants Limited | Professional & scientific | 2020 |
| Trex Solutions Limited | Information & communication | 2024 |
| Trickett Developments Limited | Real estate | 2016 |
| Trout Spares Ltd | Real estate | 2013 |
| Trust House Securities Limited | Real estate | 2023 |
| U&Z Services Limited | Professional & scientific | 2025 |
| UM Squared Limited | Wholesale & retail | 2017 |
| Utsa Ltd | Real estate | 2018 |
| VAS (International) Limited | Extraterritorial | 2021 |
| VAS Interventure Ltd | Administrative & support | 2020 |
| Vasaikar Limited | Health & social care | 2025 |
| Vasgayee Ltd | Construction | 2013 |
| Veechu Ltd | Hospitality | 2017 |
| Vekson Ltd | Wholesale & retail | 2020 |