| Earls Abbey Limited | Agriculture & fishing | 2015 |
| Easi Uplifts (Maintenance) Limited | Manufacturing | 2007 |
| Easi Uplifts (Mini Cranes) Limited | Administrative & support | 2008 |
| Easi Uplifts (N.I.) Limited | Administrative & support | 1995 |
| Eastlink Trading Ltd | Transport & logistics | 2025 |
| Eastwood Demolition Limited | Water & waste | 2015 |
| Eastwood Envirowaste (Newline) Limited | Water & waste | 2015 |
| Eastwood Envirowaste (Newtownabbey) Limited | Water & waste | 2015 |
| Eastwood Fleet Services Limited | Wholesale & retail | 1972 |
| Eastwood Group Holdings Limited | Water & waste | 2015 |
| Eastwood Limited | Construction | 1991 |
| Ecom Accounting Solutions for YOU Ltd | Professional & scientific | 2024 |
| Eden Decorators & Property Maintenance Ltd | Construction | 2018 |
| Edgar Electrical Supplies Ltd | Wholesale & retail | 2025 |
| Edward Wilson & Co., (Steeplejacks) Limited | Construction | 1975 |
| Efectis Uk/Ireland Limited | Public administration | 2017 |
| EH Foods Ltd | Hospitality | 2024 |
| EHC Central Services Ltd | Health & social care | 2021 |
| Eightball Ltd | | 2000 |
| EJC & SON Limited | Mining & quarrying | 2025 |
| EJC Construction Solutions & Training Ltd | Education | 2025 |
| EJC Plant Hire (2011) Ltd | Administrative & support | 2011 |
| EJC Propco 1A Limited | Construction | 2020 |
| EJC Propco Limited | Construction | 2019 |
| Ekco Ventures Limited | Real estate | 2025 |
| Elan Group Ltd | Financial services | 2025 |
| Electraform Limited | Information & communication | 2016 |
| Electrical Wholesale Express Limited | Wholesale & retail | 2008 |
| Electus Healthcare (Abingdon) Ltd | Health & social care | 2021 |
| Electus Healthcare (Cedarhurst) Ltd | Health & social care | 2020 |
| Electus Healthcare (Edgewater) Ltd | Health & social care | 2020 |
| Electus Healthcare (Larne) Ltd | Health & social care | 2021 |
| Electus Healthcare (Ravenhill) Ltd | Health & social care | 2023 |
| Electus Healthcare (Saintfield) Ltd | Health & social care | 2020 |
| Electus Healthcare 3 Limited | Health & social care | 2025 |
| Electus Midco Ltd | Health & social care | 2021 |
| Elite Nails & Beauty Ltd | Other services | 2018 |
| Elite Renovations & Solid Foundations Ltd | Construction | 2024 |
| Elizabeth ANN Hair Rush Park Ltd | Other services | 2016 |
| Ellen Finlay Consulting Ltd | Professional & scientific | 2026 |
| Ellis Autoparts (NI) Limited | Wholesale & retail | 2009 |
| Elly's Batting Mentality Ltd | Education | 2024 |
| Emaan Subs Ltd | Hospitality | 2014 |
| Emcg Transport Limited | Transport & logistics | 2016 |
| Emcloughlin Ltd | Professional & scientific | 2018 |
| Emerald Construction Limited | Real estate | 2004 |
| Emerald Developments (Armagh) Limited | Construction | 2014 |
| Emerald Security NI Ltd | Administrative & support | 2024 |
| Emma Ross Aesthetics Ltd | Health & social care | 2020 |
| Emma Ross Training Ltd | Health & social care | 2022 |
| Emojm Ltd | Wholesale & retail | 2023 |
| Encompass Rehab Ltd | Other services | 2022 |
| Endosurgery (N.I.) Limited | Health & social care | 2021 |
| Enefdar Ltd | Information & communication | 2025 |
| Energii Ltd | Other services | 2024 |
| Enhance Distribution Ltd | Wholesale & retail | 2014 |
| Enhance Education Ltd | Administrative & support | 2016 |
| Entedi (UK) Limited | Arts & recreation | 2019 |
| Envi Therapies Ltd | Health & social care | 2022 |
| Envisioned Property Investments Ltd | Real estate | 2025 |
| Eolian Limited | Wholesale & retail | 1987 |
| EOS Community Consulting CIC | Professional & scientific | 2020 |
| Epona Cars Ltd | Wholesale & retail | 2023 |
| Eqbi Limited | Information & communication | 2013 |
| Equipped to Care (NI) | Other services | 2026 |
| ERA Bespoke Joinery Ltd | Construction | 2025 |
| Erne Rope Access Limited | Administrative & support | 2016 |
| Erudite Digital Solutions Ltd | Information & communication | 2021 |
| ES Courier Service Ltd | Transport & logistics | 2018 |
| Euro Bros Limited | Wholesale & retail | 2025 |
| Euro Brothers Inc Ltd | Wholesale & retail | 2025 |
| Euro Car Wash and Valeting Centre Ltd | Other services | 2023 |
| Excellence Awards Ltd | Administrative & support | 2021 |
| Executive Car Hire (NI) Ltd | Administrative & support | 2013 |
| Exemplar Coffee Limited | Wholesale & retail | 2023 |
| Expertise and Diligence Ltd | Health & social care | 2017 |
| Extern Group | Professional & scientific | 2013 |
| Extern Northern Ireland | Health & social care | 1982 |
| Eyecare Carnmoney Limited | Health & social care | 2012 |
| F G Anderson & Sons Ltd | Construction | 2021 |
| F L Mccullough & Sons Limited | Extraterritorial | 1944 |
| F. B. Smyth & Co Limited | Wholesale & retail | 2003 |
| Fairfields Property Management Ltd | Real estate | 2002 |
| Fairview NI Property Investments Ltd | Real estate | 2023 |
| Fanatic Sports Apps Limited | Information & communication | 2021 |
| Farmadosis Ltd | Wholesale & retail | 2021 |
| Farset Films Ltd | Information & communication | 2017 |
| FC Tours Ltd | Administrative & support | 2023 |
| FC38 Ltd | Information & communication | 2024 |
| Fernville Properties Ltd | Households | 2017 |
| Fever Free Ltd | Manufacturing | 2019 |
| FFF Thomas Mccolgan Limited | Arts & recreation | 2025 |
| FG Engineering Commercial Ltd | Manufacturing | 2016 |
| FGC Motors (N.I.) Limited | Wholesale & retail | 2026 |
| Fh&Co Ltd | Hospitality | 2026 |
| Financial Professionals (NI) Ltd | Financial services | 2009 |
| Finn Ltd | Professional & scientific | 2017 |
| First Forklifts Limited | Professional & scientific | 2000 |
| Fittpro Studios Ltd | Arts & recreation | 2015 |
| Fktd Ltd | Health & social care | 2017 |