| FOX Scaffolding Devon Ltd | Construction | 2022 |
| Foys Independent Traders Limited | Wholesale & retail | 2023 |
| Fpenwill Limited | Professional & scientific | 2018 |
| Frame by Frame Academy Ltd | Information & communication | 2024 |
| Frames and Boxes Ltd | Wholesale & retail | 2003 |
| Francis Studios Ltd | Information & communication | 2023 |
| Frank Keeley Tax Services Ltd. | Professional & scientific | 2003 |
| Frank Pictures Limited | Information & communication | 2016 |
| Frankman Design Limited | Professional & scientific | 2013 |
| Frecos Holdings Limited | Extraterritorial | 2019 |
| Fred Christophers & SON Limited | Other services | 2010 |
| Freedom VET Limited | Professional & scientific | 2018 |
| Fremor Limited | Information & communication | 2025 |
| French Construction Limited | Extraterritorial | 2003 |
| Frequency Precision Limited | Manufacturing | 1985 |
| Fresh Start (Devon) Property Development Limited | Real estate | 2000 |
| Fresh Start (Eire) Ltd | Health & social care | 2001 |
| Freshfaceuk Ltd | Wholesale & retail | 2022 |
| Friend Computers Limited | Information & communication | 1997 |
| Frontline Community Protection Ltd | Public administration | 2015 |
| Frost Fencing Ltd | Construction | 2014 |
| Frost Plumbing Ltd | Construction | 2022 |
| Frosts Fleet Limited | Transport & logistics | 2002 |
| Fruit Marketing Limited | Administrative & support | 2019 |
| Fruitcake Consulting Limited | Wholesale & retail | 2005 |
| FSH Health & Wellbeing Ltd | Health & social care | 2021 |
| Fuelcatalyst LLP | | 2026 |
| Fuell Associates Ltd | Professional & scientific | 2022 |
| Fuelled by Caffeine (SW) Limited | Wholesale & retail | 2025 |
| Fuelled by Caffeine Limited | Hospitality | 2000 |
| Fulford and Green (SW) Ltd | Professional & scientific | 2018 |
| Fulford and Green Ltd | Professional & scientific | 2007 |
| Full Board Gaming Limited | Arts & recreation | 2022 |
| Full Circle Building Services Ltd | Construction | 2024 |
| Fuller Education Limited | Education | 2014 |
| FUN Factory Clothing Limited | Wholesale & retail | 2025 |
| Fung Sing Devon Limited | Hospitality | 2020 |
| Fuscina Limited | Manufacturing | 2025 |
| Futurae Manus Limited | Financial services | 2025 |
| Future Footings Ltd | Real estate | 2014 |
| Future of Floating Wind Limited | Professional & scientific | 2023 |
| Future Technology Creations Ltd | Professional & scientific | 2017 |
| Future Technology Resources Ltd | Education | 2017 |
| Futurebrain Ltd | Professional & scientific | 2019 |
| Fyrne Ltd | Financial services | 2021 |
| G & K Management Limited | Arts & recreation | 2011 |
| G B Paving Ltd | Construction | 2011 |
| G Eggbeer & Sons Limited | Professional & scientific | 1945 |
| G P Services (South West) Limited | Construction | 2018 |
| G R Cutland Limited | Construction | 2009 |
| G W Plumer & Sons Limited | Construction | 2001 |
| G&A Hospitality Ltd | Hospitality | 2019 |
| G&H Southwest Homes Limited | Other services | 2017 |
| G-Elec Ltd | Construction | 2022 |
| G. Thomas & Co Ltd. | Other services | 2003 |
| G. Thomson Properties Limited | Administrative & support | 2010 |
| GA Luscombe Holdings Ltd | Financial services | 2018 |
| Gadgetverse Ltd | Wholesale & retail | 2022 |
| Gaia Estates Limited | Real estate | 2018 |
| Gaia House Trust | Other services | 1990 |
| Gaia Vibrance Ltd | Other services | 2022 |
| Gallamoy Food Consultancy Ltd | Professional & scientific | 2019 |
| GAP Recruitment Limited | Administrative & support | 2010 |
| Gary Thomas Mortgages Limited | Financial services | 2016 |
| Gaskell Enterprises Limited | Wholesale & retail | 2021 |
| Gateshire Limited | Agriculture & fishing | 1974 |
| Gaucho Britannia Films Ltd | Information & communication | 2024 |
| GB Innovation Works Limited | Professional & scientific | 2013 |
| GB Property Investments Limited | Real estate | 2023 |
| GB Property Leases Limited | Real estate | 2024 |
| GB Seeds CIC | Professional & scientific | 2025 |
| GBR Marine Ltd | Professional & scientific | 2021 |
| GC Financial Advice Ltd | Financial services | 2024 |
| GDD Networks Ltd | Information & communication | 2024 |
| Gdynia Lettings Ltd | Real estate | 2024 |
| Geach Aggregates Limited | Wholesale & retail | 2021 |
| Geach Haulage Limited | Transport & logistics | 2018 |
| GEM Property Investors Ltd | Real estate | 2018 |
| GEM Testing Solutions Limited | Administrative & support | 2011 |
| Genauction Ltd | Administrative & support | 2002 |
| Gentle Recovery Ltd | Health & social care | 2024 |
| GEO Park Cafe Limited | Hospitality | 2016 |
| Geoheat Plumbing & Heating Ltd | Construction | 2022 |
| Geologic Coreholes Ltd | Construction | 2024 |
| George Bailey Investments Ltd | Financial services | 2023 |
| GEORGESTRBHB201213 LLP | | 2013 |
| Georgina Duffin Consulting Limited | Professional & scientific | 2016 |
| Georgina's Eco Cleaning Team Ltd | Administrative & support | 2018 |
| Gerard Securities Limited | Real estate | 1961 |
| German Auto Services Limited | Wholesale & retail | 2016 |
| GET Plastered Southwest Limited | Construction | 2017 |
| Gething Property Holdings Ltd | Households | 2024 |
| Geyser Water Treatment Ltd | Water & waste | 2005 |
| GHM Commerce Ltd | Wholesale & retail | 2025 |
| Ghurkas Parkside Nepalese Limited | Hospitality | 2020 |
| GIB Fire Risk Services Ltd | Public administration | 2013 |
| Gibbins Quality Meats Limited | Wholesale & retail | 2021 |
| Gibson Investment Group Limited | Extraterritorial | 2015 |
| Glanvill Contract Fixing Limited | Construction | 2014 |
| Glass Refurbishment Southwest Limited | Other services | 2020 |