| CR Enterprises (SW) Limited | Hospitality | 2019 |
| Craig Derrick Limited | Construction | 2014 |
| Craig Gahagan Wealth Management Ltd | Professional & scientific | 2023 |
| Cranham Sports LLP | | 2009 |
| Crapstone Brewery Limited | Manufacturing | 2020 |
| Creative Co Design Studio Ltd | Professional & scientific | 2023 |
| Creative Learning Solutions Limited | Education | 2009 |
| Creative Pathways. Nature. Arts. Wellbeing Ltd. | Information & communication | 2024 |
| Crisp Hotels Limited | Hospitality | 2018 |
| CRJ Billericay Holdings Limited | Hospitality | 2019 |
| CRM365 Solutions Limited | Professional & scientific | 2017 |
| Croft Management Solutions Ltd | Information & communication | 2025 |
| Crokers Grange Farm Limited | Agriculture & fishing | 2020 |
| Crome Food Technical Limited | Hospitality | 2018 |
| Crosbie Properties Ltd | Real estate | 2022 |
| Crossover Promotions Ltd | Information & communication | 1992 |
| Crown & Blade Ltd | Other services | 2026 |
| Crumbs Totnes Limited | Wholesale & retail | 2026 |
| Crystal Technica Limited | Wholesale & retail | 2004 |
| Csrchina Limited | Professional & scientific | 2004 |
| CTD Quickstep Limited | Education | 2002 |
| CTS Inspection Services Ltd | Professional & scientific | 2026 |
| Cubic Couriers Ltd | Transport & logistics | 2014 |
| Culver House Chudleigh Management Company Limited | Real estate | 2021 |
| Cummings Court Management Association Limited | Households | 1988 |
| Cura Under Your Skin Ltd | Manufacturing | 2025 |
| Curor Ltd | Information & communication | 2023 |
| Custom Business Software Limited | Information & communication | 2010 |
| CUT Cost Carpets (Devon) Ltd | Extraterritorial | 2011 |
| CV Check Limited | Administrative & support | 1997 |
| Cydrax Limited | Financial services | 2018 |
| D & a = X Investments Limited | Real estate | 2018 |
| D B Construction SW Ltd | Construction | 2024 |
| D Bayley Installations Limited | Construction | 2022 |
| D Brain & Co Limited | Wholesale & retail | 1979 |
| D C Building and Roofing Limited | Construction | 2015 |
| D Grogan Creative Ltd | Professional & scientific | 2018 |
| D J Developments Newton Abbot Limited | Construction | 2021 |
| D J Guppy & Sons Limited | Construction | 2010 |
| D M Electrical Services (Torbay) Limited | Construction | 2007 |
| D Pugh Logs Ltd | Agriculture & fishing | 2025 |
| D S Developments (SW) Limited | Construction | 2008 |
| D&D Beechey Ltd | Hospitality | 2017 |
| D&E Shears Ltd | Construction | 2018 |
| D&F Direct Ltd | Wholesale & retail | 2022 |
| D-Technic Limited | Manufacturing | 2026 |
| D.G. Weeks (Printers) Limited | Manufacturing | 2007 |
| D.J. Corbett Limited | Manufacturing | 2002 |
| DA Chef Service Ltd | Hospitality | 2024 |
| DA' Latest Limited | Information & communication | 2004 |
| Daatb Ltd | Arts & recreation | 2018 |
| Daccombe Manor Farm Limited Liability Partnership | | 2006 |
| Dacors Ltd | Professional & scientific | 2007 |
| Dainton Group Services Limited | Administrative & support | 1980 |
| Dainton Portable Building Systems Limited | Professional & scientific | 2002 |
| Dainton Portable Buildings Limited | Professional & scientific | 1973 |
| Daison Estates,Limited | Wholesale & retail | 1923 |
| Daisy Chain Property Services Limited | Administrative & support | 2021 |
| Daisychain Pre-School Ltd | Education | 2010 |
| Dalbury Court (Newton Abbot) Management Company Ltd | Households | 2015 |
| Daly Pathways Ltd | Education | 2019 |
| Dampco Limited | Administrative & support | 2003 |
| DAN Cook Carpentry & Building Ltd | Construction | 2018 |
| DAN Cook Investments Ltd | Financial services | 2023 |
| DAN Holmes Performance Ltd | Professional & scientific | 2019 |
| DAN Taylor Decorating Contractors Limited | Construction | 2015 |
| Daniel a Clarke Properties Ltd | Real estate | 2025 |
| Daniell Enterprise Ltd | Real estate | 2026 |
| Daniels Holdings (Devon) Limited | Wholesale & retail | 2018 |
| Daniels Steel (Devon) Limited | Wholesale & retail | 2015 |
| Dape Holdings Ltd | Wholesale & retail | 2022 |
| Daracombe Wholesale Ltd | Wholesale & retail | 2023 |
| Darbys Garage Limited | Wholesale & retail | 2026 |
| Dark Bar Drinks Ltd | Wholesale & retail | 2021 |
| Dark Desires Photography Studio Limited | Professional & scientific | 2023 |
| Dark Horse Developments South West Ltd | Construction | 2025 |
| Dark Horse Recruitment Ltd | Administrative & support | 2021 |
| Dark Shadows Paranormal UK Ltd | Administrative & support | 2021 |
| Darnell Services Limited | Administrative & support | 1999 |
| Darnells Audit Limited | Professional & scientific | 2014 |
| Darnells Estate Management Limited | Administrative & support | 2012 |
| Darrell Willcocks Architects Limited | Professional & scientific | 2012 |
| Dart Careers Limited | Other services | 2005 |
| Dart Ecology Ltd | Professional & scientific | 2015 |
| Dart Garage Limited | Wholesale & retail | 2016 |
| Dart Group (SW) Ltd | Construction | 2022 |
| Dart Matter Limited | Professional & scientific | 2025 |
| Dart Surveys Ltd | Professional & scientific | 2019 |
| Dartbridge Ltd | Health & social care | 2023 |
| Dartmeet Consultants Ltd | Administrative & support | 2004 |
| Dartmeet Developments Limited | Construction | 2002 |
| Dartmeet Services Limited | Construction | 1996 |
| Dartmoor Adventures LLP | | 2020 |
| Dartmoor Ambulance Service CIC | Health & social care | 2012 |
| Dartmoor Associates Limited | Financial services | 2014 |
| Dartmoor Blankets Ltd | Wholesale & retail | 2025 |
| Dartmoor Butchers Limited | Wholesale & retail | 2011 |
| Dartmoor Collective CIC | Wholesale & retail | 2020 |
| Dartmoor Commercial GAS Limited | Construction | 2016 |
| Dartmoor Court Management Company Limited | Households | 2005 |