| Virtual Path Systems Ltd | Information & communication | 2014 |
| Virtulet Ltd | Real estate | 2014 |
| Virtuosoal Ltd | Wholesale & retail | 2025 |
| Virtuous Toks Healthcare Ltd | Health & social care | 2023 |
| VIS Stores Limited | Wholesale & retail | 2018 |
| VIS Stores Newport Ltd | Wholesale & retail | 2022 |
| Visapath Pro Limited | Information & communication | 2026 |
| Vishay Newport Limited | Manufacturing | 2001 |
| Vishay UK Holding Company Limited | Professional & scientific | 2017 |
| Vision Computer Repairs Ltd | Information & communication | 2010 |
| Vision Court Management Company Limited | Real estate | 2015 |
| Vision Information Technology Ltd | Information & communication | 2006 |
| Vision Store Distribution Ltd | Wholesale & retail | 2020 |
| Vision Vantage Limited | Professional & scientific | 2025 |
| Vision Windows IW Ltd | Construction | 2019 |
| Visioncare AUM Ltd | Wholesale & retail | 2023 |
| Visioncare RNK Ltd | Wholesale & retail | 2013 |
| VISIONCARE15 Ltd | Wholesale & retail | 2023 |
| Visit Isle of Wight Limited | Information & communication | 2012 |
| Vista Homes (Wales) Ltd | Administrative & support | 2009 |
| Visual Healthcare Solutions Limited | Professional & scientific | 2009 |
| Visual Impact IOW Limited | Wholesale & retail | 2015 |
| Visual Impact Mobile Displays Limited | Administrative & support | 2018 |
| Vitalspare Limited | Extraterritorial | 2001 |
| Vitamax Supplements Ltd | Wholesale & retail | 2025 |
| Viva Espaniel Ltd | Other services | 2026 |
| Vivanaut of Wight Limited | Administrative & support | 2008 |
| Vivid Outsourcing Ltd | Professional & scientific | 2020 |
| Vixen Property Limited | Real estate | 2020 |
| VJ Reality Ltd | Real estate | 2025 |
| VJB Developments Limited | Construction | 2024 |
| Vladi's Pizza & Pasta Ltd | Hospitality | 2017 |
| Vmlilo Limited | Health & social care | 2017 |
| VNN Wholesales UK Ltd | Wholesale & retail | 2026 |
| Voce Consult Limited | Professional & scientific | 2009 |
| Vokins Rise (Ryde) Management Company Limited | Households | 1983 |
| Volehurst Limited | Transport & logistics | 1972 |
| Volt Cymru Electrical Ltd | Construction | 2026 |
| Voltaire (Cardiff) Limited | Professional & scientific | 2009 |
| Voltmaster BUS Limited | Manufacturing | 2025 |
| Voltric Mobility Technologies Limited | Information & communication | 2019 |
| VOS Developments Limited | Construction | 2019 |
| Vowen Homes Limited | Real estate | 2024 |
| VOX Industries Ltd | Professional & scientific | 2015 |
| Voyox Ltd | Other services | 2022 |
| VPR Building Services Ltd | Construction | 2021 |
| VPR Property Investments Ltd | Real estate | 2023 |
| VR LAB Group Limited | Wholesale & retail | 2020 |
| VR Mockups Ltd | Professional & scientific | 2023 |
| VRD Racing Ltd | Arts & recreation | 2023 |
| VRD Store Ltd | Wholesale & retail | 2016 |
| VRI Electrical Limited | Construction | 2013 |
| Vsuf Limited | Wholesale & retail | 2026 |
| VTR Group Ltd | Administrative & support | 2023 |
| W & E Engineering Limited | Manufacturing | 2026 |
| W & M Mcdonald (Pencarn Farms) Limited | Agriculture & fishing | 1995 |
| W a Taxi Solutions Ltd | Administrative & support | 2025 |
| W and W Foods (IOW) Ltd | Hospitality | 2018 |
| W B Wales S.E. Limited | Education | 2007 |
| W H (Surface Preperation UK) Ltd | Administrative & support | 1986 |
| W L Cymru Consulting Limited | Professional & scientific | 2023 |
| W O Sims & Sons Group Limited | Financial services | 2015 |
| W R Jones Services Ltd | Construction | 2015 |
| W&D Ltd | Real estate | 2024 |
| W&T Management Company Limited | Real estate | 2016 |
| W. Harold John (Metals) Limited | Water & waste | 1972 |
| W. Jerman & SON Limited | Wholesale & retail | 1950 |
| W.C. Management Company (Shanklin) Limited | Extraterritorial | 1989 |
| W.E.Dowds Limited | Professional & scientific | 1960 |
| W.G. Barrass Ltd | Wholesale & retail | 2003 |
| W.T.Jones(Transport)Limited | Transport & logistics | 1963 |
| W2WAVE Ltd | Information & communication | 2001 |
| WAC Construction Ltd | Administrative & support | 2016 |
| Waddles Grooming Salon Limited | Other services | 2023 |
| Wagstaff Estates Ltd | Extraterritorial | 2018 |
| WAI WAI (Cwmbran) Ltd | Hospitality | 2024 |
| Waitt Media Ltd. | Information & communication | 2012 |
| Waldendorf Medical Services Limited | Health & social care | 2019 |
| Waldon Property Management Limited | Real estate | 2025 |
| Wales & West Utilities Finance PLC | Financial services | 2008 |
| Wales & West Utilities Holdings Limited | Financial services | 2009 |
| Wales & West Utilities Limited | Energy | 2004 |
| Wales & West Utilities Pension Scheme Trustees Limited | Professional & scientific | 2006 |
| Wales and West Floor Restoration Ltd. | Construction | 2017 |
| Wales England Care Ltd | Health & social care | 2014 |
| Wales National Roofing Training Group | Education | 2009 |
| Wales T G Limited | Administrative & support | 1998 |
| Walijee ENT Ltd | Health & social care | 2024 |
| Walk Through Property Ltd | Construction | 2023 |
| Walker Construction & Properties Ltd | Construction | 2024 |
| Walker Skip Hire Ltd | Water & waste | 2018 |
| Wall Print Pro Limited | Manufacturing | 2026 |
| Waller Associates Limited | Construction | 2000 |
| Waller Property Services Limited | Extraterritorial | 2007 |
| Waller Services Limited | Construction | 2002 |
| Wallingfen Park Limited | Real estate | 1995 |
| Walnut Tree Farm Park & Education Centre | Arts & recreation | 2010 |
| Walsh Implements Limited | Manufacturing | 2015 |
| Walter Hunter & Co Limited | Professional & scientific | 2011 |
| Walter Robyn Properties Ltd | Construction | 2014 |