| Homerest Limited | Construction | 2003 |
| Homes & Stoves (NE) Limited | Construction | 2018 |
| Homes and Gardens North East Ltd | Administrative & support | 2020 |
| Homes Important 4U Ltd | Construction | 2025 |
| Homes Network Ltd | Information & communication | 2021 |
| Homes Newcastle Ltd | Construction | 2021 |
| HOMES2EXCEL Ltd | Construction | 2012 |
| HOMES2LET Limited | Professional & scientific | 1998 |
| Homesafe Equity Release Limited Partnership | | 2005 |
| Homesick Consultancy Ltd | Professional & scientific | 2024 |
| Homesol Limited | Real estate | 2023 |
| Homesource Limited | Wholesale & retail | 2021 |
| Homevision Property Services Ltd | Households | 2019 |
| Homewith Bargains Limited | Wholesale & retail | 2012 |
| Homey Haus Ltd | Real estate | 2023 |
| Homing Bird Theatre CIC | Arts & recreation | 2023 |
| Honest Smile Ltd | Wholesale & retail | 2025 |
| Honey Property Group Ltd | Real estate | 2022 |
| Honeybadger Holdings Ltd | Professional & scientific | 2014 |
| Honeybadger Solutions Limited | Professional & scientific | 2002 |
| Honeybird Studios Limited | Information & communication | 2023 |
| Hong.K Limited | Hospitality | 2025 |
| Honjet LLP | | 2024 |
| Honorables Dating Network Ltd | Information & communication | 2024 |
| Honorables News Network Limited | Manufacturing | 2024 |
| Hood Street Estates Limited | Real estate | 2021 |
| Hoods Greenhouse Limited | Wholesale & retail | 2012 |
| Hook Pictures Ltd | Information & communication | 2012 |
| Hooked-On Group Limited | Professional & scientific | 2015 |
| Hooker & Young Limited | Other services | 2004 |
| Hopax Europe Limited | Professional & scientific | 1999 |
| Hope Beyond Borders CIC | Professional & scientific | 2025 |
| Hope Chisunzi Ltd | Health & social care | 2021 |
| Hope Holdings Ltd | Households | 2025 |
| Hope's Happy Hounds Limited | Agriculture & fishing | 2018 |
| Hope's Properties NE Ltd | Real estate | 2024 |
| Hope(Helping Other People to Excel) Community Interest Company | Administrative & support | 2025 |
| Hopeful Solutions Ltd | Education | 2023 |
| Hopescaff Ltd | Construction | 2026 |
| Hoppers Signs Limited | Manufacturing | 2002 |
| Hoppers Wood Ltd | Professional & scientific | 2025 |
| Hoppr Protein Ltd | Manufacturing | 2023 |
| Hopscotchnewcastle Limited | Hospitality | 2025 |
| Hopwood VAT Limited | Professional & scientific | 2012 |
| Horao Neurolabs Ltd | Health & social care | 2025 |
| Hore Exors of RA Decd Limited | Construction | 2010 |
| Horia's Buisness Ltd | Construction | 2024 |
| Horizon & Wellbeing Ltd | Other services | 2026 |
| Horizon Cheerleading CIC | Arts & recreation | 2023 |
| Horizon Estate NCL Ltd | Real estate | 2026 |
| Horizon Global Services Ltd | Health & social care | 2022 |
| Horizon Wholesalers Ltd | Wholesale & retail | 2025 |
| Horse Weighbridge North East Limited | Professional & scientific | 2021 |
| Horseley Bridge & Thomas Piggott Limited | | 1946 |
| Horses & Humanity Community Interest Company | Education | 2023 |
| Horsley Property Services Limited | Construction | 2001 |
| Horticulture Specialist Nursery Ltd | Agriculture & fishing | 2023 |
| Horton Grange Country House Hotel Limited | Hospitality | 2005 |
| HOS Skin Therapy Limited | Other services | 2024 |
| Hospital Electrical Services Limited | Construction | 2026 |
| Hospitality Enterprises Limited | Hospitality | 2023 |
| Hospitality HR Management Ltd | Administrative & support | 2019 |
| Hostel Traders Ltd | Manufacturing | 2017 |
| Hot Stone Pizza House Limited | Hospitality | 2023 |
| Hot Yoga Newcastle Ltd | Arts & recreation | 2019 |
| Hotel 52 (Parkmore) Limited | Hospitality | 2018 |
| Hotel Dog Ltd | Extraterritorial | 2014 |
| Hotel Operations Limited | Hospitality | 2004 |
| Hotspur Architecture Limited | Professional & scientific | 2022 |
| Hotspur Capital Partners Limited | Financial services | 2017 |
| Hotspur Electrical Ltd | Professional & scientific | 2020 |
| Hotspur Management Ltd | Real estate | 2004 |
| Houblon Financial Services Ltd | Financial services | 2025 |
| Houghton LE Spring TEC Limited | Wholesale & retail | 2022 |
| Hoults Holdings Limited | Professional & scientific | 2011 |
| Hoults Limited | Real estate | 1936 |
| Hound Hub Collective Ltd | Wholesale & retail | 2026 |
| House 4 Pets Ltd | Wholesale & retail | 2020 |
| House and Properties Ltd. | Real estate | 2004 |
| House Doctors NE Ltd | Construction | 2025 |
| House of Aroma Ltd | Hospitality | 2025 |
| House of Azia Ltd | Hospitality | 2022 |
| House of Balloons North East Limited | Administrative & support | 2021 |
| House of Blessings Cleaning Services Ltd | Administrative & support | 2025 |
| House of Brooke Interior Design Studio Ltd | Professional & scientific | 2026 |
| House of Cars - Newcastle Ltd | Wholesale & retail | 2023 |
| House of Coria Limited | Real estate | 2026 |
| House of Crumbs Limited | Hospitality | 2013 |
| House of Desserts (N.E.) Ltd | Hospitality | 2021 |
| House of Hyderabad Limited | Hospitality | 2026 |
| House of Languages Limited | Professional & scientific | 2026 |
| House of Lavb Ltd | Other services | 2025 |
| House of Meat Limited | Wholesale & retail | 2024 |
| House of Qidwai Ltd | Wholesale & retail | 2025 |
| House of Scents Limited | Wholesale & retail | 2021 |
| House of Trade (NE) Ltd | Wholesale & retail | 2020 |
| House of Yohfee Ltd | Other services | 2026 |
| HOUSE54 Studios Ltd | Information & communication | 2023 |
| Housewarm Limited | Construction | 2011 |
| Hoverdrone Limited | Construction | 2012 |