| Chestaer Road Shawarma Ltd | Hospitality | 2025 |
| Chester Health Limited | Health & social care | 2024 |
| Chester LE Street Health Limited | Health & social care | 2015 |
| Chestnut BIO Polymers Ltd | Professional & scientific | 2019 |
| Chetty & DAS Limited | Health & social care | 2010 |
| Cheung Family Ltd | Hospitality | 2020 |
| Cheviot Catering and Refrigeration Limited | Wholesale & retail | 2010 |
| Cheviot Learning Trust | Education | 2011 |
| Cheviot Limited | Information & communication | 2025 |
| Cheviot Marine Limited | Professional & scientific | 2026 |
| Cheviot Spray Coats Ltd | Construction | 2025 |
| Chew Properties Ltd | Real estate | 2025 |
| CHG (Newcastle) Limited | Hospitality | 1990 |
| Chhatwals Ltd | Real estate | 2019 |
| Chhipa Limited | Information & communication | 2016 |
| CHI & OTU Limited | Health & social care | 2017 |
| CHI CHI Healthcare (N E ) Ltd | Health & social care | 2015 |
| Chibo Cafe Ltd | Hospitality | 2023 |
| Chic-Antique Ltd | Wholesale & retail | 2009 |
| Chicago Acquisitions Limited | Real estate | 2013 |
| Chichester Mews (Westoe) Management Company Limited | Real estate | 2005 |
| Chichester Park Hotel Holdings Limited | Financial services | 2022 |
| Chick N Crust Ltd | Hospitality | 2025 |
| Chickalicious Ltd | Hospitality | 2018 |
| Chickalicious Newcastle Limited | Hospitality | 2026 |
| Chicken Hutt (NE) Ltd | Administrative & support | 2018 |
| Chieftain Fabrications Ltd | Manufacturing | 2017 |
| Chigcon Ltd | Professional & scientific | 2025 |
| Childcare Policy and Resources Hub Ltd | Education | 2026 |
| Children's Trusted Care Limited | Health & social care | 2025 |
| Chilicious Limited | Wholesale & retail | 2024 |
| Chilies Ltd | Wholesale & retail | 2025 |
| Chillgoodsuk Ltd | Wholesale & retail | 2022 |
| Chilli Studios (Newcastle and Gateshead Arts Studio) Limited | Health & social care | 2004 |
| Chillingham Food & Wines Ltd | Wholesale & retail | 2025 |
| Chillingham Hand Car Wash Ltd | Wholesale & retail | 2016 |
| Chillingham Properties Limited | Real estate | 2023 |
| Chillingham Road Chippy Limited | Hospitality | 2016 |
| Chillingham Road Store Limited | Wholesale & retail | 2025 |
| Chillingham Wines Limited | Wholesale & retail | 2013 |
| Chimney Sweep Activities Ltd | Health & social care | 2018 |
| Chin Chin Chinese Ltd | Hospitality | 2026 |
| Chin Chin NE Ltd | Hospitality | 2023 |
| China International Logistics and Express Mail Ltd | Wholesale & retail | 2019 |
| China Long Ltd. | Wholesale & retail | 2019 |
| Chinastar Takeout Limited | Hospitality | 2024 |
| Chinese Catering Management Limited | Hospitality | 2018 |
| Chinni Enterprises Ltd | Wholesale & retail | 2026 |
| Chip & Fish Limited | Hospitality | 2025 |
| Chipchase Medical Services Ltd | Health & social care | 2011 |
| Chipchase Sporting Club Limited | Arts & recreation | 2024 |
| Chirton Properties Limited | Real estate | 2018 |
| Chisa Maxwell Consultancy Ltd | Health & social care | 2010 |
| Chiswick News Ltd | Information & communication | 2024 |
| Chits Group International Limited | Wholesale & retail | 2025 |
| Chits Security Events and Catering Limited | Hospitality | 2025 |
| Chitsfoods Limited | Wholesale & retail | 2026 |
| Chitshealthcare Limited | Administrative & support | 2024 |
| CHJ Law Limited | Professional & scientific | 2017 |
| Chjm Events Limited | Professional & scientific | 2022 |
| Chlfinlay Ltd | Hospitality | 2025 |
| Chloe Watson Ltd | Administrative & support | 2019 |
| Chmuk Ltd | Wholesale & retail | 2024 |
| Chocohugs Ltd | Wholesale & retail | 2023 |
| Chocolate Chip Photography Limited | Professional & scientific | 2013 |
| Chogar Ltd | Real estate | 2023 |
| Chohan Care Unlimited | Real estate | 2013 |
| Choice Traders Ltd | Wholesale & retail | 2016 |
| Choose Water Limited | Wholesale & retail | 2015 |
| Chop Chop (NE) Ltd | Hospitality | 2024 |
| Chop-Ooo Global Limited | Hospitality | 2017 |
| Chopren Limited | Extraterritorial | 2024 |
| Chopwell Garage Services Ltd | Wholesale & retail | 2023 |
| Chopwell Management Company Limited | Households | 2013 |
| Chopwell Village Store Ltd | Wholesale & retail | 2022 |
| CHORTON4 | Financial services | 2013 |
| Chowdhury Family Property Ltd | Households | 2019 |
| Chowington Holdings Ltd | Real estate | 2019 |
| Chowrasta Group Limited | Hospitality | 2025 |
| CHR Events Ltd | Arts & recreation | 2024 |
| CHR Financial Solutions Limited | Financial services | 2025 |
| Chris Barker Limited | Professional & scientific | 2023 |
| Chris Cain Engineering Services Ltd | Administrative & support | 2014 |
| Chris Care Mobile Services Ltd | Administrative & support | 2024 |
| Chris Cassidy Civil Engineering Ltd | Construction | 2017 |
| Chris D Brown Electrical Limited | Construction | 2022 |
| Chris Elwood Properties Ltd | Real estate | 2024 |
| Chris Fraser Investments Limited | Financial services | 2020 |
| Chris Gill Tree Surgery Ltd | Other services | 2009 |
| Chris Gooding (IFA) Ltd | Financial services | 1998 |
| Chris Patrick Advisory LLP | | 2021 |
| Chris Patrick Consulting LLP | | 2020 |
| Chrisdell Limited | Real estate | 1973 |
| Christ Church Newcastle | Other services | 2008 |
| Christ's Gospel to the Nations CIC | Other services | 2024 |
| Christandzee Property Ltd | Real estate | 2025 |
| Christchurch Management (Newcastle) Limited | Real estate | 2005 |
| Christophe Ollerenshaw Limited | Health & social care | 2016 |
| Christopher James Owens Limited | Professional & scientific | 2018 |
| Christopher Mcerlane Ltd | Professional & scientific | 2017 |