| Buzzbar Forest Hall Ltd | Wholesale & retail | 2019 |
| Buzzbar Ltd | Hospitality | 2018 |
| Buzzymum Ltd | Wholesale & retail | 2026 |
| BV Fashion Ltd | Wholesale & retail | 2026 |
| BW Graphic Designs Ltd | Professional & scientific | 2016 |
| BW Medical Accountants Ltd | Professional & scientific | 2013 |
| BW Supply Limited | Wholesale & retail | 2024 |
| BWS (NE) Limited | Administrative & support | 2015 |
| BX1 Services Limited | Administrative & support | 2026 |
| BXB Interiors & Architecture Limited | Professional & scientific | 2014 |
| BY Annabelle Limited | Wholesale & retail | 2020 |
| BY Meow Ltd | Manufacturing | 2023 |
| BY Olesea Therapy & Spa Ltd | Other services | 2018 |
| BYD Blossom Landscape Architecture Limited | Professional & scientific | 2019 |
| Byes Solar UK Limited | Extraterritorial | 2014 |
| Byhome Limited | Other services | 2000 |
| Byker Beauty Parlour Ltd | Other services | 2022 |
| Byker Body Repair Ltd | Wholesale & retail | 2024 |
| Byker Community Coop CIC | Hospitality | 2026 |
| Byker Express Limited | Hospitality | 2024 |
| Byker Limited | Real estate | 2023 |
| Byker TEC Limited | Wholesale & retail | 2022 |
| Byker-It Ltd | Other services | 2024 |
| Byland Lodge (Management) Limited | Real estate | 2012 |
| Bymb. Collective Limited | Professional & scientific | 2022 |
| Byrne Investments Ltd | Real estate | 2000 |
| Byron Heights Residents Management Company Limited | Households | 2019 |
| Bytelabs Innovations Ltd | Wholesale & retail | 2023 |
| Bytoo Ltd | Wholesale & retail | 2023 |
| Bywell View (Management) Limited | Real estate | 1999 |
| C & G Electrical Inspection Ltd | Construction | 2019 |
| C & C Entertainment Ltd | Arts & recreation | 2012 |
| C & H (NE) Ltd | Hospitality | 2014 |
| C & H Interiors Ltd | Construction | 2018 |
| C & H Psychotherapies Ltd | Health & social care | 2023 |
| C & I Healthcare Services Ltd | Health & social care | 2019 |
| C & J Harries North East Ltd | Manufacturing | 2025 |
| C & W Investments Limited | Financial services | 2014 |
| C a Beresford Limited | Construction | 2017 |
| C a Portsmouth Limited | Manufacturing | 2001 |
| C Buchanan Properties Ltd | Real estate | 2024 |
| C C 8 Express Ltd | Hospitality | 2021 |
| C Consultancy Ltd | Professional & scientific | 2025 |
| C D & C Ltd | Hospitality | 2012 |
| C D Hall Opticians Ltd | Wholesale & retail | 2018 |
| C F Realisations 2023 Limited | Professional & scientific | 2011 |
| C Guthrie Properties Ltd | Real estate | 2025 |
| C Investments Limited | Administrative & support | 2016 |
| C J Patterson Building Contractors Limited | Construction | 2011 |
| C K Digital Ltd | Professional & scientific | 2025 |
| C L Addy Consulting Ltd | Professional & scientific | 2019 |
| C M Jordan Building (NE) Ltd | Construction | 2019 |
| C P Motors (North East) Limited | Wholesale & retail | 2011 |
| C Talbot Limited | Professional & scientific | 2016 |
| C W Taylor Property Services Limited | Real estate | 2016 |
| C&B Auto Magic Ltd | Manufacturing | 2024 |
| C&C Security NE Ltd | Administrative & support | 2025 |
| C&D Access Ltd | Professional & scientific | 2014 |
| C&D Access Training Ltd | Construction | 2020 |
| C&D Construct Ltd | Construction | 2021 |
| C&D Event Styling Ltd | Hospitality | 2021 |
| C&L Courier Services Ltd | Transport & logistics | 2022 |
| C&M Tiling Ltd | Construction | 2020 |
| C&N Sales Limited | Wholesale & retail | 2025 |
| C&P North East Limited | Real estate | 2025 |
| C&S Access and Inspection Ltd | Professional & scientific | 2015 |
| C-A Trading Ltd | Wholesale & retail | 2023 |
| C-Wealth Ltd | Professional & scientific | 2013 |
| C. D. Jennings Limited | Professional & scientific | 2020 |
| C. Sainter Enterprises Ltd | Administrative & support | 2021 |
| C.H. Steavenson Limited | Wholesale & retail | 1993 |
| C.H.Brown,Limited | Real estate | 1923 |
| C.Harveyproductions Ltd | Arts & recreation | 2025 |
| C.M.T Residential Limited | Real estate | 2025 |
| C.S.E.A. Limited | Manufacturing | 1985 |
| C4 Sightcare Newcastle Limited | Wholesale & retail | 2012 |
| C929 Planet Ltd | Real estate | 2024 |
| CA Heat Pumps Limited | Construction | 2008 |
| CA Installation Services Limited | Construction | 2015 |
| CA Tweedy Limited | Construction | 2025 |
| CA Wind Turbine Services Limited | Manufacturing | 2023 |
| Ca&B Ltd | Professional & scientific | 2024 |
| Caa-Gbg (Baby & Beauty) Limited | Wholesale & retail | 2018 |
| CAB GAS Ltd | Energy | 2023 |
| CAB Help Limited | Transport & logistics | 2025 |
| CAB Recycling Ltd | Water & waste | 2021 |
| Cabello Hair Extensions Ltd | Other services | 2025 |
| Cabinet Limited | Information & communication | 2019 |
| Cable Project Services Ltd | Administrative & support | 2022 |
| Cabrito Goat Meat Limited | Manufacturing | 2016 |
| Cacao Brew Ltd | Manufacturing | 2018 |
| Cacoon Ltd | Manufacturing | 2026 |
| CAD Bar (NE) Limited | Hospitality | 2019 |
| Cadzow Estates Limited | Professional & scientific | 2018 |
| Caelian House Ltd | Wholesale & retail | 2026 |
| Caesars Travel Ltd | Administrative & support | 2018 |
| CAF Renewables Limited | Construction | 2025 |
| Cafe 1901 Ltd | Extraterritorial | 2014 |
| Cafe Bar One Limited | Hospitality | 2004 |
| Cafe by Design Ltd | Hospitality | 2022 |