| Zerodrytime (South Tyneside) Limited | Other services | 2014 |
| Zerodrytime Franchising Limited | Administrative & support | 2008 |
| Zerodrytime Gateshead & Tyne Valley Ltd | Other services | 2018 |
| Zerodrytime Northumberland Ltd | Other services | 2011 |
| Zerolight Limited | Information & communication | 2014 |
| Zest Aura Limited | Professional & scientific | 2025 |
| Zesty Group Ltd | Professional & scientific | 2017 |
| Zeta B Group Ltd | Real estate | 2025 |
| Zeta Education Ltd | Education | 2025 |
| ZG Business Services Limited | Professional & scientific | 2015 |
| ZG Locums Ltd | Wholesale & retail | 2023 |
| ZHA NE Ltd | Professional & scientific | 2026 |
| Zhafir Locum Limited | Wholesale & retail | 2003 |
| Zhen Kitchen Limited | Hospitality | 2023 |
| Zhen Xinn Ltd | Other services | 2022 |
| Zheng Best Massage Ltd | Other services | 2025 |
| Zheng YU Massage Limited | Health & social care | 2017 |
| Zheng YU Property Rental Co Ltd | Real estate | 2025 |
| ZHI WEI Ltd | Hospitality | 2019 |
| Zhutek Investment LLP | | 2021 |
| Ziba Collections North East Ltd. | Wholesale & retail | 2017 |
| Zibahhealthcare Ltd | Health & social care | 2025 |
| Ziesto Limited | Arts & recreation | 2016 |
| Zileo Limited | Information & communication | 2020 |
| Zille Mart Ltd | Wholesale & retail | 2025 |
| Zinchi International Limited | Administrative & support | 2025 |
| Zingbat Services Ltd | Information & communication | 2019 |
| Zinny Maid Cleaning Services Ltd | Administrative & support | 2025 |
| Zinoc Properties Ltd | Real estate | 2023 |
| Zion ARK Capital Ltd | Real estate | 2025 |
| Zionest Care Group Ltd | Health & social care | 2014 |
| Zips Cabs Ltd | Transport & logistics | 2022 |
| Ziyara & Hans Ltd | Hospitality | 2022 |
| Zizi Property Ltd | Households | 2024 |
| Zjth Ltd | Administrative & support | 2024 |
| ZK Barber 1 Ltd | Other services | 2024 |
| ZK Barbers Ltd | Other services | 2023 |
| ZK Property Ltd | Real estate | 2025 |
| ZKY Family Ltd | Households | 2026 |
| ZLA Logistics Ltd | Transport & logistics | 2026 |
| ZLA Same Day Couriers Ltd | Transport & logistics | 2025 |
| ZM28 Ltd | Real estate | 2024 |
| ZM7 Properties Ltd | Real estate | 2025 |
| Zman Limited | Wholesale & retail | 2022 |
| ZMM Limited | Wholesale & retail | 2013 |
| Zmobbarber Limited | Other services | 2026 |
| Zoball Ltd | Wholesale & retail | 2025 |
| ZOE the Wedding Florist Ltd | Wholesale & retail | 2023 |
| Zolo Properties Ltd | Real estate | 2025 |
| Zonat Limited | Real estate | 2014 |
| Zone 9 Entertainment Ltd | Arts & recreation | 2021 |
| Zone Apartments Ltd | Households | 2021 |
| Zonked Ltd | Administrative & support | 2024 |
| Zonlytiks Ltd | Information & communication | 2022 |
| Zonne Limited | Extraterritorial | 2021 |
| Zoomies Private Hire Ltd | Transport & logistics | 2025 |
| Zora Marketing Ltd | Professional & scientific | 2023 |
| Zoyue Commercial Finance Limited | Financial services | 2021 |
| ZR Finance Ltd | Professional & scientific | 2025 |
| ZR94 Holdings Ltd | Financial services | 2025 |
| Zrsas Ltd | Real estate | 2019 |
| Zsatti Ltd | Wholesale & retail | 2025 |
| ZSC Consulting Limited | Professional & scientific | 2025 |
| ZSI Auto Ltd | Wholesale & retail | 2016 |
| ZT Properties Limited | Real estate | 2019 |
| ZT Shots Limited | Wholesale & retail | 2021 |
| ZTA Consultancy Ltd | Health & social care | 2024 |
| Ztcreative Limited | Information & communication | 2014 |
| Ztelvio Limited | Extraterritorial | 2022 |
| Zula Restaurant Ltd | Hospitality | 2024 |
| Zurityne Global Talent Management Limited | Administrative & support | 2023 |
| Zwanenberg Technical Services Limited | Professional & scientific | 2007 |
| ZWE Properties Ltd | Real estate | 2023 |
| Zweet Limited | Information & communication | 2025 |
| ZX Ecom Limited | Wholesale & retail | 2023 |
| ZX Limited | Real estate | 2004 |
| ZY Investment Ltd | Real estate | 2022 |
| Zynk Holdings Limited | Information & communication | 2016 |
| Zynk Software Limited | Information & communication | 2002 |
| Zyra Offical Ltd | Other services | 2026 |
| Zyrax Limited | Wholesale & retail | 2025 |
| Zytech Auto Parts Limited | Wholesale & retail | 2025 |
| Zytronic Displays Limited | Manufacturing | 1943 |
| Zytronic Glass Products Limited | Extraterritorial | 1999 |
| Zytronic PLC | Professional & scientific | 1999 |
| ZZ Traders PVT Limited | Wholesale & retail | 2024 |
| [NO Pro-Blame] Limited | Manufacturing | 2025 |
| Âpre Hair Concept Ltd | Other services | 2023 |