| Rcad Consulting Limited | Professional & scientific | 2025 |
| Reactionless Drive Limited | Manufacturing | 2005 |
| REC2REC Search Ltd | Administrative & support | 2016 |
| Reciprocal Property Limited | Real estate | 2022 |
| Red Balloon Learner Centre - North East | Education | 2010 |
| Red Panda Technologies Ltd | Information & communication | 2005 |
| Red ROW Garden HUT CIC | Wholesale & retail | 2018 |
| Redsash Ltd | Professional & scientific | 2025 |
| Reedcode Ltd | Information & communication | 2019 |
| Rejoice Care Services Limited | Health & social care | 2024 |
| Rejuvenate Skin & LHR Ltd | Other services | 2023 |
| Remcap Group Limited | Financial services | 2025 |
| Remi Consulting Ltd | Professional & scientific | 2015 |
| Remsid Ltd | Real estate | 2025 |
| Renders Online Ltd | Wholesale & retail | 2012 |
| Renwick Animal & Pet Cremation Services Limited | Professional & scientific | 2024 |
| REP - Build Limited | Construction | 2002 |
| RETAINERS4U Ltd | Health & social care | 2023 |
| Rezai Property Solutions Ltd. | Construction | 2023 |
| Rezwana Properties Ltd | Real estate | 2023 |
| Rgsc North East Ltd | Construction | 2020 |
| Rhysgar Limited | Administrative & support | 2018 |
| Rich Rothwell Cycling Limited | Arts & recreation | 2020 |
| Richard Thompson Accountants Limited | Extraterritorial | 2009 |
| Rickard 1936 Ltd. | Real estate | 2007 |
| Ride Classics Ltd | Wholesale & retail | 2017 |
| Riderdesigned Ltd | Manufacturing | 2023 |
| Ridgeline Coffee Ltd | Hospitality | 2026 |
| Rigo Plant Hire Limited | Administrative & support | 2026 |
| Rimside Limited | Real estate | 2020 |
| Riverside Dinner Limited | Hospitality | 2022 |
| Riverworks Ltd | Construction | 2013 |
| RJ Henderson Ltd | Administrative & support | 2026 |
| RJB Consultancy Ltd | Professional & scientific | 2022 |
| RJC Building Services Limited | Manufacturing | 2013 |
| Rlca Ltd | Administrative & support | 2026 |
| Rlongman Ltd | Information & communication | 2026 |
| RMB Building Solutions Limited | Construction | 2026 |
| RMM Holdings Limited | Real estate | 2020 |
| Rmtv Energy Limited | Construction | 2019 |
| Rmtv Entertainment Limited | Construction | 2019 |
| RNH Estimating Services Ltd | Construction | 2014 |
| RNR Scaffolding & Roofing Ltd | Construction | 2020 |
| Road Runner Recovery NE Ltd | Wholesale & retail | 2024 |
| Roadline Hire Limited | Construction | 2020 |
| Roadline North East Limited | Water & waste | 2017 |
| ROB Sadler Live Audio Ltd | Arts & recreation | 2018 |
| Robert Alistair Ltd | Construction | 2025 |
| Robert Laverick Joinery Limited | Construction | 2016 |
| Robin Digital Ltd | Information & communication | 2021 |
| Robin Wilson Lets Ltd | Real estate | 2022 |
| Robinson Retreats Ltd | Hospitality | 2024 |
| Robinson-Gay (Cabinet Makers) Limited | Manufacturing | 1999 |
| Rockpool Fish & Shellfish Ltd | Manufacturing | 2019 |
| Roger's Timber Ltd | Wholesale & retail | 2021 |
| ROK 48/52 LLP | | 2022 |
| ROL Limited | Agriculture & fishing | 2002 |
| Romeo Tango Aviation Limited | Arts & recreation | 2012 |
| Roof Kerb Solutions Ltd | Wholesale & retail | 2023 |
| Roots Dental Ltd | Health & social care | 2023 |
| Rose Allan Ltd | Administrative & support | 2024 |
| Rose Atelier Ltd | Professional & scientific | 2026 |
| Rosemont Capital Holdings Ltd | Financial services | 2026 |
| Rosemont Real Estate Advisory Limited | Real estate | 2026 |
| Rothbury Development Corporation Ltd | Real estate | 2026 |
| Rothbury Golf Club Limited | Arts & recreation | 2003 |
| Rothley Hall Management Company Limited | Households | 1990 |
| Rowell Property Ltd | Real estate | 2021 |
| Rowenters Technical Services Limited | Professional & scientific | 2009 |
| Royal Sovereign House Manchester Street Apartments Management Company Limited | Hospitality | 2013 |
| RP & KK Ltd | Hospitality | 2026 |
| RP Integrity Limited | Manufacturing | 2024 |
| RS Data Science Limited | Professional & scientific | 2025 |
| RS Sandhu and Sons Property Ltd | Real estate | 2026 |
| RSG Civils Ltd | Construction | 2021 |
| Ruby Property Group Ltd | Real estate | 2021 |
| Ruff Ridge Ltd | Wholesale & retail | 2025 |
| RULE28 Ltd | Information & communication | 2024 |
| Runaway Northumberland Limited | Hospitality | 2025 |
| Rural Building Supplies (N.E.) Limited | Wholesale & retail | 2022 |
| Rural Design Centre Limited | Professional & scientific | 2019 |
| Rural Heating North East Limited | Construction | 2025 |
| Rural Partners Limited | Agriculture & fishing | 1999 |
| Rushforth Property Ltd | Real estate | 2024 |
| Ruth Dixon Content Design Limited | Information & communication | 2020 |
| Ryan Lyall Plumbing & Heating Ltd | Construction | 2025 |
| Ryderco Ltd | Real estate | 2020 |
| RYM Property Limited | Information & communication | 2024 |
| S & S Design Ltd | Manufacturing | 2019 |
| S J Marshall Building Limited | Construction | 2025 |
| S&L Installing Ltd | Construction | 2025 |
| S.A.Proudlock Ltd | Households | 2025 |
| S.D.M Properties Limited | Hospitality | 2016 |
| SA91 Properties Limited | Real estate | 2020 |
| Saddleworth Digital Ltd | Administrative & support | 2020 |
| SAF Scaffolding Solutions Ltd | Construction | 2025 |
| Safe Secure Access Solutions Limited | Manufacturing | 2026 |
| Safeguard (North East) Limited | Construction | 2011 |
| Sales People Recruitment Ltd | Administrative & support | 2014 |
| Salon @ the Yard Limited | Other services | 2018 |