| SAI Vishnu Ltd | Information & communication | 2013 |
| Saif Social and Health Care Homes Ltd | Hospitality | 2014 |
| Saii & Co Limited | Professional & scientific | 2007 |
| Sain Limited | Transport & logistics | 2020 |
| Saina Care Limited | Health & social care | 2025 |
| Saira Khalid Ltd | Wholesale & retail | 2026 |
| Sajjad Butt UK Limited | Health & social care | 2009 |
| Sakian Retails Limited | Wholesale & retail | 2015 |
| Sales and Trading Ltd | Construction | 2025 |
| Salista Properties Ltd | Real estate | 2024 |
| Salista UK Ltd | Administrative & support | 2018 |
| Salkass Medical Limited | Health & social care | 2026 |
| Sallooz Ltd | Transport & logistics | 2018 |
| Salonaz Ltd | Wholesale & retail | 2020 |
| SAM Bedford Properties Ltd | Real estate | 2025 |
| SAM Car Hub Ltd | Wholesale & retail | 2025 |
| SAM the JAM Ltd | Hospitality | 2025 |
| Sama Alrosha Travel and Tourism Company Ltd | Professional & scientific | 2024 |
| SAN Greal Limited | Transport & logistics | 2018 |
| Sana Immigration Ltd | Professional & scientific | 2025 |
| Sanascendant Development Group Ltd | Real estate | 2026 |
| Sandbox Ventures Ltd | Wholesale & retail | 2022 |
| Sandbrick Limited | Construction | 2013 |
| Sandton Management Ltd | Real estate | 2017 |
| Sanexporto Ltd | Financial services | 2025 |
| Sang LEE (Carshalton) Ltd | Hospitality | 2019 |
| Sanguardian Property Management Ltd | Administrative & support | 2026 |
| Saniyama Ltd | Wholesale & retail | 2023 |
| Sapphire Emerald Limited | Health & social care | 2026 |
| Sapphire Horizon Consulting Ltd | Education | 2025 |
| Saracen Global Investments Ltd | Construction | 2019 |
| Saretta Ltd | Wholesale & retail | 2020 |
| Sargo Properties Ltd | Real estate | 2019 |
| Sarkar Health Services Ltd | Health & social care | 2024 |
| Sarmad Global Accountancy Services Ltd | Professional & scientific | 2011 |
| Saroya Limited | Construction | 2021 |
| Sarvazay Limited | Wholesale & retail | 2026 |
| Sarvik Ltd | Hospitality | 2024 |
| Sarwar Marketing Solutions Ltd | Information & communication | 2024 |
| Sash Healthcare Limited | Health & social care | 2013 |
| Sash One Limited | Real estate | 2020 |
| Sash Properties Investment Limited | Real estate | 2018 |
| Sathubs Limited | Wholesale & retail | 2024 |
| Satkohis Empire Holdings Ltd | Financial services | 2020 |
| Satkohis Empire Ltd | Administrative & support | 2013 |
| Satkohis Estates Ltd | Real estate | 2023 |
| Satkohis Motors Ltd | Wholesale & retail | 2015 |
| Satkohis Real Estates Ltd | Real estate | 2025 |
| Saudi Medics Ltd | Wholesale & retail | 2021 |
| Savov & SON Ltd | Construction | 2019 |
| Sawim Ltd | Wholesale & retail | 2024 |
| Sayegh and Sayegh LLP | | 2018 |
| Sazir-Damz Limited | Health & social care | 2021 |
| Scaffoldbuilders Limited | Administrative & support | 2025 |
| Scale Work Force Ltd | Administrative & support | 2011 |
| Scaleupplans Ltd | Real estate | 2019 |
| Scanit Ltd | Wholesale & retail | 2025 |
| Schipor Construction Ltd | Construction | 2015 |
| School Insight Limited | Information & communication | 1999 |
| Scissors CUT Ltd | Administrative & support | 2016 |
| Scott Storey Personal Training Limited | Health & social care | 2013 |
| Scripting Solutions Limited | Information & communication | 2011 |
| SD Removals and Builders Ltd | Transport & logistics | 2023 |
| SDK Ltd | Real estate | 2018 |
| Sdnr Limited | Real estate | 2024 |
| Seafood Home Europe Limited | Extraterritorial | 2014 |
| Seashore Vegetables and Fruits UK Ltd | Wholesale & retail | 2025 |
| Secret Heaven Limited | Wholesale & retail | 2024 |
| Secure Sparks Electrical Ltd | Construction | 2025 |
| Secure Square Ltd | Real estate | 2025 |
| Secure West London Ltd | Administrative & support | 2019 |
| Secured Electrical Limited | Manufacturing | 2025 |
| Securotix Ltd | Wholesale & retail | 2026 |
| Secyour Ltd | Construction | 2023 |
| Seedpy Car Hire Ltd | Wholesale & retail | 2023 |
| Seely Ltd | Transport & logistics | 2024 |
| Seer Trading Limited | Transport & logistics | 2018 |
| Sehc Limited | Other services | 2021 |
| Sehc Wholesale Limited | Wholesale & retail | 2020 |
| Sekar Limited | Real estate | 2024 |
| Selaj Ltd | Construction | 2025 |
| Selden Holding Real Estate Ltd | Real estate | 2024 |
| Select Land Developers Ltd | Real estate | 2023 |
| Selfie Tire Repair Trading Limited | Wholesale & retail | 2025 |
| Semaal Limited | Health & social care | 2013 |
| SEN Nanny in London Ltd | Education | 2023 |
| Seniot Ltd | Manufacturing | 2023 |
| Sensible Healthcare Ltd | Health & social care | 2020 |
| SEO Syrup Ltd | Information & communication | 2011 |
| Seopapa Ltd | Hospitality | 2021 |
| Sephoras Fame Salon Ltd | Wholesale & retail | 2018 |
| Services AM Ltd | Construction | 2024 |
| Servicing Zone Ltd | Wholesale & retail | 2024 |
| Setbox Events Ltd | Administrative & support | 2014 |
| Seven 11 Express Ltd | Wholesale & retail | 2024 |
| SFR 6 Maintenance Ltd | Real estate | 2025 |
| SG Electrical & Heating Ltd | Construction | 2017 |
| SG Legal Services Limited | Professional & scientific | 2026 |
| SH2A'S Production Limited | Professional & scientific | 2022 |
| SHA CAI Ltd | Construction | 2022 |