| Dowoa Limited | Education | 2025 |
| Doxa DEO Consultancy Ltd | Professional & scientific | 2014 |
| Doxa Services Ltd | Other services | 2016 |
| DPB Ventures Ltd | Professional & scientific | 2024 |
| DPI Marketing Ltd | Professional & scientific | 2024 |
| DR Laraeb Ltd | Health & social care | 2026 |
| DR Margaret's Clinic Limited | Administrative & support | 2019 |
| Dragomanski Ltd | Construction | 2019 |
| Drape Method Ltd | Professional & scientific | 2026 |
| Draw Investments Ltd | Real estate | 2017 |
| DRC Corp Ltd | Wholesale & retail | 2009 |
| DRD Construction Limited | Construction | 2021 |
| Dreamy Transformations Ltd | Other services | 2019 |
| Drinko Ltd | Wholesale & retail | 2019 |
| Drinks Wholesale Group Holdings Ltd | Wholesale & retail | 2021 |
| Drinks Wholesale Group Ltd | Wholesale & retail | 1984 |
| Drop Zero Digital Ltd | Professional & scientific | 2021 |
| DRS Luxury Limited | Wholesale & retail | 2025 |
| DRY Waterproofing Limited | Construction | 2011 |
| Dryroof London Limited | Construction | 2026 |
| DS2K Limited | Health & social care | 2019 |
| DSA Sabin Ltd | Transport & logistics | 2018 |
| Dshanks Ltd | Health & social care | 2021 |
| Dtmexpressco Ltd | Wholesale & retail | 2026 |
| Dtools Limited | Wholesale & retail | 2025 |
| DUA Foundation | Health & social care | 2012 |
| Dube Legacy Enterprise Ltd | Financial services | 2026 |
| Dubelo Investments Ltd | Real estate | 2025 |
| Dulwich Accountancy Services Ltd | Professional & scientific | 2010 |
| Dunya International Limited | Extraterritorial | 2010 |
| Dunya News Limited | Information & communication | 2010 |
| Dunya TV Limited | Extraterritorial | 2010 |
| Duong Property Limited | Real estate | 2021 |
| Durga PA Limited | Real estate | 2021 |
| Durkhanai Ltd | Wholesale & retail | 2021 |
| Durodos Limited | Wholesale & retail | 2019 |
| Durshenaa Limited | Real estate | 2024 |
| Dusty House Brown Street Limited | Real estate | 2017 |
| Dusty House Hollins Limited | Real estate | 2024 |
| Dusty House Macc. Limited | Real estate | 2018 |
| Dwell Luxury Estates Limited | Real estate | 2025 |
| Dwellinks Ltd | Real estate | 2025 |
| Dworld Trading Ltd | Wholesale & retail | 2026 |
| Dyno DCO Ltd | Construction | 2020 |
| D’S Auto Repairs Ltd | Wholesale & retail | 2025 |
| E & G Eagle Construction Limited | Construction | 2024 |
| E & S Building Services Ltd | Construction | 2008 |
| E Premium Ltd | Wholesale & retail | 2023 |
| E Retail Spot Ltd | Wholesale & retail | 2020 |
| E U Building Alliance Limited | Construction | 2016 |
| E&L Family Group Limited | Financial services | 2022 |
| E&L Homes Limited | Real estate | 2020 |
| E&L Service Road Freehold Limited | Real estate | 2024 |
| E&L Service Road Limited | Real estate | 2023 |
| E&L Stays Limited | Hospitality | 2025 |
| E&V Eco Solutions Ltd | Administrative & support | 2026 |
| E-Fenk Ltd. | Wholesale & retail | 2011 |
| E-Spot Limited | Real estate | 2005 |
| E-Star Services Ltd | Health & social care | 2022 |
| E.A.T.O.W. Entity C.I.C. | Education | 2026 |
| E.H.E Property Investing Ltd | Real estate | 2022 |
| E2 Consultants Ltd | Hospitality | 2019 |
| E3 Elevate Events by Ehsaan Ltd | Professional & scientific | 2025 |
| EA Global Business Women Network Ltd | Administrative & support | 2018 |
| EAD Plumbing and Heating Specialist Limited | Construction | 2025 |
| Eagle City Church Ltd | Education | 2012 |
| Eaglesacademiccentre Ltd | Education | 2018 |
| Eaman Building Services Limited | Construction | 2019 |
| Early Nurture Ltd | Education | 2015 |
| Early Years Connect Ltd | Administrative & support | 2019 |
| Eason Properties Ltd | Real estate | 2020 |
| East Land Leather Ltd | Wholesale & retail | 2026 |
| Eastern European Health Hub CIC | Public administration | 2025 |
| Easy MOT Ltd | Wholesale & retail | 2019 |
| Easy Route Logistics Ltd | Transport & logistics | 2026 |
| Easy Shipping Ltd | Transport & logistics | 2003 |
| Easy Shop Mitcham Ltd | Wholesale & retail | 2024 |
| Easyhomz Limited | Information & communication | 2025 |
| Easytecheuropeanduk Limited | Other services | 2018 |
| Eaze PAY Ltd | Information & communication | 2019 |
| Eazy Accident Claims Ltd | Professional & scientific | 2012 |
| Eazy Carz Limited | Wholesale & retail | 2014 |
| Eazycom Ltd | Information & communication | 2013 |
| ECH Logistics Ltd | Manufacturing | 2019 |
| ECH Services Ltd | Transport & logistics | 2016 |
| Echo Lima Group Ltd | Information & communication | 2022 |
| Eclipse Concierge Ltd | Other services | 2021 |
| Eco Cleaning and Landscaping Limited | Administrative & support | 2024 |
| Ecomfinity Ltd | Wholesale & retail | 2025 |
| Economic Development Incorporated Ltd | Professional & scientific | 2021 |
| Ecowipe Cleaning Services Limited | Administrative & support | 2025 |
| Ecsi Limited | Hospitality | 2003 |
| EDC Relocation Limited | Households | 2022 |
| Eden Cars Limited | Wholesale & retail | 2015 |
| Eden Living Limited | Health & social care | 2025 |
| Eden Shack Limited | Wholesale & retail | 2023 |
| Edenway Homes Ltd | Real estate | 2024 |
| Edgehill Technology Ltd | Extraterritorial | 2020 |
| EDITH7 Services Limited | Professional & scientific | 2024 |
| Education Network Development Scheme CIC | Education | 2023 |