| Enorth Staffing Ltd | Administrative & support | 2014 |
| Enpowersystems Limited | Information & communication | 2015 |
| Enrich Beauty (MK) Ltd | Other services | 2016 |
| Ensaunya Ltd | Administrative & support | 2020 |
| Enso Sportswear Limited | Manufacturing | 2019 |
| Ensy Consulting Ltd | Professional & scientific | 2025 |
| Entcancercare Ltd | Health & social care | 2015 |
| Enter Employment Ltd | Administrative & support | 2023 |
| Enterpoint Properties Limited | Real estate | 2009 |
| Enterprise Analysts Limited | Information & communication | 2023 |
| Enterprise Business Ally Solutions Limited | Information & communication | 2010 |
| Enterprise Minds UK Ltd | Information & communication | 2021 |
| Enterprise Resource Management Limited | Extraterritorial | 1999 |
| Enterprise Solution Limited | Health & social care | 2015 |
| Enterprise Transformation Consulting Limited | Professional & scientific | 2014 |
| Entertainment Hub Ltd | Wholesale & retail | 2009 |
| Entertainment International Ltd | Information & communication | 2018 |
| Entex Business Solution Ltd | Professional & scientific | 2015 |
| Entex Investment Limited | Real estate | 2023 |
| Entice MS Ltd | Wholesale & retail | 2024 |
| Entrepot Ltd | Transport & logistics | 2026 |
| Entrepreneur Communities Ltd | Professional & scientific | 2025 |
| Entrepreneur Fusion Ltd | Information & communication | 2014 |
| Entropy Consultancy Ltd | Information & communication | 2023 |
| Entrue Limited | Information & communication | 2022 |
| Entyre Group Limited | Real estate | 2019 |
| Entys Curtis Ltd | Information & communication | 2014 |
| Enums Ltd | Information & communication | 2008 |
| Enviro Collections Ltd | Water & waste | 2017 |
| Environmental Building Solutions Limited | Professional & scientific | 1998 |
| Environmental Capital Limited | Professional & scientific | 2006 |
| Environmental Design Solutions Limited | Information & communication | 1988 |
| Environmental Markets Board Limited | Public administration | 2026 |
| Envirotec Management Services (UK) Ltd | Construction | 2011 |
| Envision Healthcare Training Limited | Health & social care | 2020 |
| Envlp Ltd | Construction | 2024 |
| Envorium Limited | Wholesale & retail | 2017 |
| Enyas Coffee Limited | Wholesale & retail | 2025 |
| Enzo Pilla Carpentry Limited | Construction | 2019 |
| Enzo's Catering Ltd | Hospitality | 2012 |
| EOG Property Management Limited | Hospitality | 2024 |
| EON Graphics Limited | Professional & scientific | 2023 |
| EON Services Limited | Education | 2017 |
| Eonli Ltd | Information & communication | 2010 |
| EOS Strategies Limited | Information & communication | 2025 |
| EP Electrics Ltd | Construction | 2021 |
| EP Practice (Milton Keynes) Limited | Health & social care | 2014 |
| EPA Group Ventures Limited | Financial services | 2024 |
| EPA Investments Limited | Financial services | 2020 |
| EPA Media Limited | Information & communication | 2025 |
| EPA Property Investments Limited | Real estate | 2023 |
| Epage Design Consultants Limited | Administrative & support | 2012 |
| Epcs Solutions Ltd | Administrative & support | 2019 |
| Ephesus MK Ltd | Hospitality | 2020 |
| Epic Action Media Ltd | Extraterritorial | 2025 |
| Epic Haulage Limited | Transport & logistics | 2025 |
| Epic Pies Ltd | Manufacturing | 2017 |
| Epicpoker Limited | Information & communication | 2011 |
| Epicure Limited | Extraterritorial | 1993 |
| Epigram Ventures Limited Partnership | | 2014 |
| EPR Loco Ltd | Administrative & support | 2024 |
| Epsidata Ltd. | Information & communication | 2014 |
| Epsilon Civil Engineering Ltd | Construction | 2024 |
| EQN Outsourced Services Limited | Professional & scientific | 2018 |
| Equal London Fashion Clothing Ltd | Manufacturing | 2018 |
| Equalibrium Ltd | Professional & scientific | 2016 |
| Equalis Holdings Ltd | Financial services | 2025 |
| Equalis Trading Ltd | Other services | 2025 |
| Equality Advocates Ltd | Administrative & support | 2016 |
| Equalsmart Ltd | Wholesale & retail | 2023 |
| Equanimous IT Solutions Ltd | Information & communication | 2014 |
| Equay Limited | Professional & scientific | 2013 |
| Equine Saddlers UK Ltd | Wholesale & retail | 2024 |
| Equinox Cleaning Service Ltd | Administrative & support | 2024 |
| Equinutrients Limited | Wholesale & retail | 2024 |
| Equita Corporate Finance LLP | | 2008 |
| Equity Security Services Ltd | Administrative & support | 2010 |
| Equitynest Ventures Ltd | Real estate | 2025 |
| ER Design Limited | Professional & scientific | 2024 |
| ER Prime Properties Limited | Real estate | 2019 |
| ERA DE Tramuntana Limited | Hospitality | 2021 |
| Eralddo Construction Ltd | Construction | 2026 |
| Erasmus Education Ltd | Education | 2025 |
| Eratu Mohc Ltd | Real estate | 2017 |
| Eray & Cedin Solutions Ltd. | Information & communication | 2018 |
| Ercap Consulting Ltd | Information & communication | 2018 |
| Erdei Merch Aisle Ltd | Wholesale & retail | 2022 |
| Erfit Ltd | Construction | 2026 |
| Ergonoeng UK Ltd | Professional & scientific | 2023 |
| Eric Bridget Enterprise Limited | Health & social care | 2018 |
| Eric T Handy Services Ltd | Construction | 2024 |
| Ericus Drylining Limited | Construction | 2023 |
| Eridu Ltd | Real estate | 2021 |
| Erigan Ltd. | Information & communication | 2016 |
| Erinion Ltd | Manufacturing | 2024 |
| Eriviva Properties Ltd | Real estate | 2024 |
| Ernest and Edith Limited | Information & communication | 2015 |
| Ernest Charles Holdings Ltd | Real estate | 2021 |
| Ernest Miller Ltd | Financial services | 2020 |
| Ernshia Group Limited | Hospitality | 2026 |