| Dudley Plant Hire Limited | Construction | 1978 |
| Dudman Group Trading Limited | Mining & quarrying | 2013 |
| Duelstone Ltd | Information & communication | 2022 |
| Dugout Tech Company Limited | Information & communication | 2025 |
| Dulari Automotive Limited | Wholesale & retail | 2018 |
| Dumade Property Management Ltd | Real estate | 2023 |
| Dumas Accounting and Business Support Limited | Professional & scientific | 2002 |
| Dumi's Healthcare Ltd | Health & social care | 2014 |
| Dunamic Limited | Education | 2025 |
| Duncan Grove Ltd | Professional & scientific | 1999 |
| Duncan Osterley Management Company Limited | Households | 1981 |
| Duncan Roofing & Building Ltd | Construction | 2021 |
| Duncan Scott Associates Ltd | Professional & scientific | 2013 |
| Duncan Sinclair Consulting Ltd | Professional & scientific | 2019 |
| Duncan's Dog Co Ltd | Other services | 2020 |
| Duncan's Doggy Daycare Limited | Other services | 2013 |
| Duncombe Street Community House Limited | Arts & recreation | 2010 |
| Duncombe Street Garage Ltd | Wholesale & retail | 2023 |
| Duncow Bar & Grill Ltd | Hospitality | 2020 |
| Dunemount Consulting Limited | Information & communication | 2025 |
| Dung Beetle Solutions Limited | Professional & scientific | 2014 |
| Dungrange Limited | Real estate | 2011 |
| Dunn Investments Limited | Administrative & support | 1995 |
| Dunnis Limited | Professional & scientific | 2012 |
| Dunnottar Developments Limited | Manufacturing | 2005 |
| Duns TEW Kitchens Limited | Administrative & support | 2007 |
| Dunstable Glass 2020 Limited | Construction | 2019 |
| Dunwell Care Ltd | Hospitality | 2019 |
| DUO Logic Limited | Professional & scientific | 2019 |
| Duomo Avenue Limited | Wholesale & retail | 2025 |
| Duravit UK Limited | Wholesale & retail | 2001 |
| Durka Traders Ltd | Wholesale & retail | 2019 |
| Durndell Building Surveyors Ltd | Professional & scientific | 2022 |
| Dusila Ltd | Wholesale & retail | 2025 |
| Dustcontrol UK Limited | Manufacturing | 1996 |
| Dutch Fries Shack Ltd | Hospitality | 2019 |
| Duxbury Associates Ltd | Professional & scientific | 2017 |
| DV & Sons Properties Ltd | Real estate | 2021 |
| DV8 Future Living Limited | Construction | 2022 |
| Dvdo Consultancy Ltd | Administrative & support | 2023 |
| DVI Resilience Ltd | Administrative & support | 2021 |
| DVJ Consulting Limited | Information & communication | 2023 |
| DVM Change Management Limited | Professional & scientific | 2012 |
| DW Consulting Limited | Information & communication | 2013 |
| DW MK Transport Ltd | Transport & logistics | 2023 |
| Dwelling Space Ltd | Hospitality | 2013 |
| DWG Construction Ltd | Construction | 2022 |
| DWG Services MK Ltd | Construction | 2022 |
| DWI Heritage Ltd | Construction | 2023 |
| Dwnr & Co. Limited | Professional & scientific | 2013 |
| Dwseal Limited | Construction | 2019 |
| DWT Transporting Ltd | Transport & logistics | 2021 |
| Dwyer Accountants Ltd | Professional & scientific | 2016 |
| Dwyer LUX Painting and Cleaning Limited | Construction | 2024 |
| Dxbbathrooms Limited | Wholesale & retail | 2024 |
| DXK Properties Ltd | Real estate | 2022 |
| Dxma UK Limited | Wholesale & retail | 2020 |
| Dyaco UK Limited | Wholesale & retail | 2018 |
| Dyazo UK Ltd | Wholesale & retail | 2020 |
| DYD Ltd | Professional & scientific | 2015 |
| Dyfed Telecom Ltd | Information & communication | 2012 |
| Dymond Property Consulting Limited | Information & communication | 2014 |
| Dynamic Air Limited | Manufacturing | 1983 |
| Dynamic Crowd Measurement Ltd | Information & communication | 2020 |
| Dynamic Design Electrical Limited | Construction | 2019 |
| Dynamic Driving Academy Limited | Transport & logistics | 2018 |
| Dynamic Engineers Limited | Professional & scientific | 2022 |
| Dynamic Healthcare Consultancy Ltd | Health & social care | 2019 |
| Dynamic Imaging Analytics Limited | Manufacturing | 2015 |
| Dynamic Industries Limited | Information & communication | 1996 |
| Dynamic Ledgers Ltd | Information & communication | 2019 |
| Dynamic Moves Services Limited | Transport & logistics | 2020 |
| Dynamic Shooting Systems (World-Wide) Limited | Administrative & support | 2016 |
| Dynamic Steel Limited | Manufacturing | 2019 |
| Dynamic Technologies Europe Ltd | Information & communication | 1999 |
| Dynamic Technologies Group Ltd | Information & communication | 2021 |
| Dynamic Threads Ltd | Manufacturing | 2018 |
| Dynamic Transport Limited | Transport & logistics | 2015 |
| Dynamic Water Systems (UK) Ltd | Construction | 2019 |
| Dynamicchildcare Limited | Health & social care | 2026 |
| Dynamics Business Consulting Limited | Information & communication | 2017 |
| Dynamics Business Solutions Ltd | Information & communication | 2007 |
| Dynamics Management Services Limited | Information & communication | 2011 |
| Dynamics Property Investments Ltd | Real estate | 2021 |
| Dynamicspro (UK) Ltd | Information & communication | 2014 |
| Dynamo Composites Limited | Manufacturing | 2016 |
| Dynamo Diabetes Ltd | Education | 2017 |
| Dynamo Mortgages Limited | Financial services | 2006 |
| Dyocense Limited | Information & communication | 2024 |
| Dyrect Ltd | Real estate | 2026 |
| DZE UK Ltd | Construction | 2022 |
| Dzodzo Limited | Wholesale & retail | 2011 |
| E & a Studios Ltd | Arts & recreation | 2013 |
| E & E Logistics Limited | Transport & logistics | 2024 |
| E & G MK Solutions Ltd | Construction | 2022 |
| E & M Electronic Services Ltd | Other services | 2008 |
| E & S Albion Limited | Real estate | 2017 |
| E & S Heating & Ventilation Limited | Manufacturing | 1985 |
| E & S Medical Services Ltd | Health & social care | 2024 |
| E & S Services Limited | Financial services | 2016 |