| Donmia London Limited | Manufacturing | 2023 |
| Donna M Russell Limited | Administrative & support | 2018 |
| Don’S MK Services Ltd | Construction | 2021 |
| Doodar App Limited | Information & communication | 2021 |
| Doodar Limited | Information & communication | 2021 |
| Doodle on the Go Ltd | Wholesale & retail | 2024 |
| Dooga Ltd. | Other services | 2002 |
| Doolittle Management Company Limited | Households | 2001 |
| Doolittle Yard Management Company Limited | Real estate | 2004 |
| Door Key Property Management Limited | Real estate | 2024 |
| Door Sentry Ltd | Other services | 2024 |
| DOR Construction Ltd | Construction | 2025 |
| Doraemum Limited | Hospitality | 2023 |
| Dorani Investment Ltd | Real estate | 2023 |
| Dorhar Health Limited | Administrative & support | 2019 |
| Dorkom Ltd | Wholesale & retail | 2025 |
| Dormee Health Limited | Health & social care | 2022 |
| Dorpat Homes Ltd | Hospitality | 2021 |
| Dorridge (London) Limited | Real estate | 2006 |
| Dosa Company (MK) Ltd | Hospitality | 2025 |
| Dostoo Limited | Real estate | 2019 |
| DOT Transport Limited | Transport & logistics | 2021 |
| Dotcom Consultancy Limited | Information & communication | 2006 |
| Dotcrm Ltd | Professional & scientific | 2024 |
| Doterra (Europe) Ltd | Wholesale & retail | 2009 |
| Dotonthemap Ltd | Construction | 2018 |
| Dotts Business Solutions Limited | Professional & scientific | 2012 |
| Dotty Developments Limited | Real estate | 2021 |
| Double Impact Events Ltd | Administrative & support | 2025 |
| Double R Glass and Roofing Systems Limited | Manufacturing | 2000 |
| Double SIX Services Limited | Information & communication | 2020 |
| Doubleton Estates Ltd | Real estate | 2025 |
| Dough&Co Milton Keynes Limited | Hospitality | 2021 |
| Douglas Jackson Limited | Administrative & support | 2007 |
| Douglas Roofing and Leadwork Ltd | Construction | 2021 |
| Douglas Ryan Group Limited | Wholesale & retail | 2026 |
| Dove Beauty Academy Ltd | Education | 2023 |
| Dove Garden Management Ltd | Other services | 2025 |
| Dovetail Dwellings Ltd | Real estate | 2024 |
| Downer Holdings Limited | Financial services | 2022 |
| Downer Properties Limited | Real estate | 2022 |
| Downing Ltd Limited | Transport & logistics | 2013 |
| Downs Barn Stores Limited | Wholesale & retail | 2014 |
| Dowse Engineering Limited | Manufacturing | 2005 |
| Dowson Press Limited | Manufacturing | 2013 |
| DOX Films Limited | Information & communication | 2018 |
| DOX Productions Limited | Information & communication | 1998 |
| Doxagate Limited | Professional & scientific | 2009 |
| Doxford Property Group Limited | Real estate | 2021 |
| Doyles of London Limited | Wholesale & retail | 2012 |
| DP Associates GB Limited | Arts & recreation | 2008 |
| DP Estates TBL Limited | Hospitality | 2003 |
| DP Leisure GB Limited | Arts & recreation | 2008 |
| DP Logistics Ltd | Transport & logistics | 2023 |
| DP Realty Limited | Construction | 1993 |
| DP Sourcing Limited | Wholesale & retail | 2026 |
| DP12 Properties Ltd | Real estate | 2025 |
| DPC Rushden Limited | Construction | 2011 |
| DPF Guru Ltd | Wholesale & retail | 2024 |
| DPG Holdings 2 Limited | Financial services | 2025 |
| DPG Holdings Limited | Professional & scientific | 2006 |
| DPI Group Transport Ltd | Transport & logistics | 2021 |
| Dpkh Limited | Information & communication | 2016 |
| DPM Consulting Ltd | Professional & scientific | 2023 |
| Dpraj Limited | Wholesale & retail | 2025 |
| DPS Direction Limited | Financial services | 2003 |
| DPW Energy Services Ltd | Professional & scientific | 2017 |
| DR Akram & Associates Limited | Health & social care | 2006 |
| DR Charlie Easmon Limited | Health & social care | 2011 |
| DR Christine Bassindale Limited | Health & social care | 2020 |
| DR Harry Consulting Ltd | Education | 2025 |
| DR HG Aesthetics Ltd | Other services | 2019 |
| DR Mali Ltd | Wholesale & retail | 2025 |
| DR Marketing and Analytics Ltd | Professional & scientific | 2021 |
| DR Okuzu & Co Ltd | Health & social care | 2016 |
| DR Sharma’S Homeopathy (UK) Ltd | Health & social care | 2024 |
| DR Vaida Healthcare Ltd | Health & social care | 2025 |
| DR. Gruber Ltd | Professional & scientific | 2021 |
| DR. Innes Limited | Health & social care | 2011 |
| DR. NK Clinics Ltd | Other services | 2026 |
| Dr.Dhivya's Divaa Ayurvedic Skincare Ltd | Wholesale & retail | 2023 |
| Dr.Shadi Ltd | Health & social care | 2025 |
| DR002 Ltd | Administrative & support | 2023 |
| DRA Contracts Limited | Administrative & support | 2013 |
| Dragon Boat 2022 Ltd | Hospitality | 2022 |
| Dragon Mountain City Project Limited | Professional & scientific | 2024 |
| Dragon Retail 543 Limited | Wholesale & retail | 2025 |
| Dragon Technology Group Limited | Professional & scientific | 2026 |
| Dragon Traders Ltd | Wholesale & retail | 2016 |
| Dragonacre Limited | Professional & scientific | 1982 |
| Dragons Netball Club Ltd | Education | 2026 |
| Dragonwood Investment (UK) Ltd | Hospitality | 2022 |
| Drainage Sentry Ltd | Other services | 2024 |
| Drainflow Solutions Limited | Construction | 2016 |
| Drainwatch Ltd | Other services | 2024 |
| Drake Performance Ltd | Real estate | 2018 |
| DRAWN2DIGITAL Ltd | Information & communication | 2019 |
| Draxia Ltd | Professional & scientific | 2012 |
| Draxia Tech Limited | Information & communication | 2014 |
| Drayton Construction Services Limited | Professional & scientific | 2018 |