| Uptown Girl MK Ltd | Other services | 2016 |
| Uptown Style Ltd | Professional & scientific | 2022 |
| Upvc Online Ltd | Wholesale & retail | 2010 |
| Upways Group Ltd | Wholesale & retail | 2025 |
| UR Closet Services Ltd | Wholesale & retail | 2021 |
| UR Investments Limited | Real estate | 2009 |
| Ur-Nammu Publishing Ltd | Information & communication | 2026 |
| Urban & Rural (Ampthill) Limited | Real estate | 2016 |
| Urban & Rural (Bedford) Limited | Real estate | 2018 |
| Urban and Rural Milton Keynes Limited | Real estate | 2015 |
| Urban and Rural New Homes Limited | Real estate | 2026 |
| Urban Automotive Ltd | Wholesale & retail | 2013 |
| Urban Bespoke Styling Limited | Manufacturing | 2019 |
| Urban Charging Limited | Construction | 2018 |
| Urban Crane Ltd | Information & communication | 2016 |
| Urban Crest Property Management Ltd | Real estate | 2025 |
| Urban Eden MK Limited | Other services | 2007 |
| Urban Edition Limited | Wholesale & retail | 2026 |
| Urban Food Brands Limited | Administrative & support | 2016 |
| Urban Gate Property Solutions Ltd | Real estate | 2025 |
| Urban Group Holdings Limited | Financial services | 2021 |
| Urban Gym Ltd | Other services | 2024 |
| Urban Link Holdings Limited | Financial services | 2023 |
| Urban Luxury Windows Ltd | Construction | 2025 |
| Urban Manufacturing Company Limited | Manufacturing | 2020 |
| Urban Minds Engineering Limited | Construction | 2022 |
| Urban Nooks Ltd | Real estate | 2025 |
| Urban OM Yoga Ltd | Arts & recreation | 2022 |
| Urban Roots MK Limited | Construction | 2019 |
| Urban Sense Limited | Professional & scientific | 2008 |
| Urban Skies (Holdings) Limited | Professional & scientific | 2023 |
| Urban Skies Ltd | Professional & scientific | 2019 |
| Urban Smoke Kitchen Limited | Hospitality | 2025 |
| Urban Solutions (MK) Ltd | Construction | 2024 |
| Urban Targets Ltd | Arts & recreation | 2023 |
| Urban Verve Ltd | Wholesale & retail | 2026 |
| Urbanart Projects Ltd | Construction | 2024 |
| Urbanpowa Limited | Wholesale & retail | 2007 |
| Urbix Technologies Limited | Information & communication | 2026 |
| Urgent Transit Limited | Transport & logistics | 2017 |
| Uridium Group Limited | Information & communication | 2024 |
| Urlglobe Ltd | Information & communication | 2011 |
| USA Fashion (UK) Limited | Wholesale & retail | 1996 |
| USA Properties Limited | Real estate | 1999 |
| USA Top Nails Ltd | Other services | 2024 |
| USABLE365 Limited | Construction | 2025 |
| Usave Emea Ltd | Administrative & support | 2023 |
| Ushodaya Services Ltd | Information & communication | 2013 |
| Usmac UK Limited | Wholesale & retail | 2014 |
| Usman Finance Ltd | Health & social care | 2022 |
| USP Design Ltd | Professional & scientific | 2022 |
| Uspec Solutions Limited | Construction | 2015 |
| Uspec Solutions Services Ltd | Construction | 2026 |
| Usrising UK Ltd | Construction | 2017 |
| UT International Ltd | Wholesale & retail | 2019 |
| Utano Ltd | Wholesale & retail | 2025 |
| Uu-Tech Consulting Ltd | Information & communication | 2025 |
| UUI Limited | Manufacturing | 2015 |
| UV View Ltd | Other services | 2024 |
| UW Group Limited | Wholesale & retail | 2021 |
| UX Craft Ltd | Information & communication | 2019 |
| Uxbridge Maritime Services Limited | Extraterritorial | 2018 |
| Uxbridge Special Projects Limited | Administrative & support | 2019 |
| Uzaklar Construction and Development Limited | Construction | 2019 |
| Uzma Holdings Ltd | Real estate | 2025 |
| V & a Auto Repairs Ltd | Wholesale & retail | 2022 |
| V Composites Ltd | Manufacturing | 2022 |
| V Eleven Consultancy Ltd | Information & communication | 2025 |
| V Formation Solutions Ltd | Professional & scientific | 2020 |
| V Group International Limited | Wholesale & retail | 2002 |
| V Property Investments Ltd | Real estate | 2025 |
| V S Boateng & Associates Limited | Administrative & support | 2024 |
| V S Consultancy Limited | Professional & scientific | 2007 |
| V Star Group Ltd | Financial services | 2025 |
| V Star Ltd | Wholesale & retail | 2006 |
| V Track Global Tech Limited | Information & communication | 2024 |
| V V Brothers Limited | Wholesale & retail | 2012 |
| V É L E R N Limited | Wholesale & retail | 2026 |
| V&G Healthcare Ltd | Health & social care | 2020 |
| V&G Properties Ltd | Real estate | 2022 |
| V&H Group Ltd | Real estate | 2021 |
| V&M Cleaning Company Ltd | Administrative & support | 2025 |
| V-Shu Limited | Wholesale & retail | 2023 |
| V-Square Technologies Limited | Information & communication | 2012 |
| V. Drought & Co Limited | Professional & scientific | 1993 |
| V.And S.P. Ltd | Transport & logistics | 2023 |
| V.O Distribution Ltd | Transport & logistics | 2021 |
| V24 Estates Ltd | Real estate | 2024 |
| VA Medical and Professional Services Ltd | Health & social care | 2022 |
| Vaaafrica Limited | Wholesale & retail | 2025 |
| Vaamg Consulting Limited | Information & communication | 2016 |
| Vaamg Holding Limited | Financial services | 2022 |
| Vacuum Interrupters Testing and Supply Europe Ltd | Manufacturing | 2013 |
| Vacuum Technologies Limited | Professional & scientific | 2012 |
| Vadevalor Limited | Financial services | 2019 |
| Vaess (UK) Limited | Wholesale & retail | 2024 |
| Vagivi Tech Ltd | Information & communication | 2026 |
| Vagtech Limited | Wholesale & retail | 2005 |
| Vaidya Services Limited | Health & social care | 2018 |
| Vaishika Ltd | Real estate | 2024 |