| Striking Cards Ltd | Wholesale & retail | 2025 |
| Striking Events Limited | Administrative & support | 2022 |
| Stroke Recovery UK Limited | Health & social care | 2024 |
| Stromsholm Limited | Wholesale & retail | 2000 |
| Strong Energy Construction Ltd | Construction | 2026 |
| Strong Pilates UK Limited | Arts & recreation | 2022 |
| Strong Property Design Ltd | Construction | 2020 |
| Strongdiesel Limited | Other services | 2015 |
| Strongest Property Ltd | Real estate | 2024 |
| Stronglaminate Ltd | Other services | 2024 |
| Stroud International Co., Limited | Wholesale & retail | 2021 |
| Structech Ltd | Professional & scientific | 2017 |
| Structura Developments Ltd | Construction | 2026 |
| Structuraltech Ltd | Manufacturing | 2025 |
| Struttyourmutts Ltd | Other services | 2024 |
| Stuart James (BSF) Limited | Construction | 2024 |
| Stuart Sams FM Limited | Professional & scientific | 2019 |
| Students Stay Properties Ltd | Real estate | 2023 |
| Studiero Ltd | Education | 2020 |
| Studio 24 Digital Ltd | Information & communication | 2018 |
| Studio 29 Digital Limited | Information & communication | 2018 |
| Studio 47 Limited | Real estate | 2021 |
| Studio 59 Tattoo's Ltd | Other services | 2011 |
| Studio @22 Ltd | Other services | 2022 |
| Studio Barbers Limited | Other services | 2018 |
| Studio C3D Ltd | Professional & scientific | 2015 |
| Studio Chehade Ltd | Professional & scientific | 2015 |
| Studio Clips Ltd | Other services | 2026 |
| Studio DE Beauvoir Ltd | Professional & scientific | 2023 |
| Studio Facet Ltd | Professional & scientific | 2021 |
| Studio Holmwood Ltd | Construction | 2017 |
| Studio Regency Holdings Limited | Financial services | 2024 |
| Studio Regency Ltd | Real estate | 2016 |
| Studio Stylus Ltd | Other services | 2015 |
| Studio Temwa Ltd | Information & communication | 2022 |
| STUDIO18LONDON Ltd | Information & communication | 2024 |
| Studioageli Surveying Limited | Professional & scientific | 2014 |
| Studiogrp Ltd | Professional & scientific | 2014 |
| Studiomatica Ltd | Professional & scientific | 2020 |
| Study Orbit London Ltd | Education | 2026 |
| Studydent Ltd | Information & communication | 2026 |
| Studyhow Consultancy Ltd | Professional & scientific | 2025 |
| Stump Cross Inn Limited | Hospitality | 2025 |
| Stumpeye Limited | Manufacturing | 2023 |
| Stunning Interior Designs Ltd | Construction | 2018 |
| Stunts 4 Reel Ltd | Arts & recreation | 2014 |
| STUNTS4ACTION Ltd | Arts & recreation | 2018 |
| STW Property Limited | Real estate | 2025 |
| STX Next Limited | Information & communication | 2022 |
| Stygian Ltd | Information & communication | 2020 |
| Stylan Ltd | Information & communication | 2023 |
| Style and Strategies Ltd | Professional & scientific | 2026 |
| Style Build Ltd | Construction | 2024 |
| Style Club Group Ltd | Wholesale & retail | 2026 |
| Styledbysimrah Ltd | Other services | 2025 |
| Styleinn Ltd | Wholesale & retail | 2024 |
| Styrenic Solutions Ltd | Wholesale & retail | 2017 |
| Styx Properties Limited | Real estate | 2022 |
| Suari by Two Ltd | Wholesale & retail | 2025 |
| Subhan Consulting Limited | Professional & scientific | 2017 |
| Sublime Technology Limited | Information & communication | 2004 |
| Sublimiti Ltd | Real estate | 2024 |
| Subrickzz Ltd | Information & communication | 2024 |
| Subscripto Technologies Ltd | Professional & scientific | 2011 |
| Suburban Habitat Ltd | Administrative & support | 2023 |
| Subysphoto Ltd | Professional & scientific | 2006 |
| Subzero Acuk Limited | Energy | 2025 |
| Success FAB Motivation Ltd | Manufacturing | 2025 |
| Success Temple | Other services | 2022 |
| Successors Holding Limited | Financial services | 2024 |
| Such a Trivial Ltd | Professional & scientific | 2024 |
| SUD Shipping & Trading Ltd | Wholesale & retail | 2018 |
| Suds & Shine Events Ltd | Administrative & support | 2025 |
| Suffolk Growers Limited | Agriculture & fishing | 2018 |
| Sugati Ltd | Wholesale & retail | 2000 |
| Suiderland Plase UK Limited | Wholesale & retail | 2019 |
| Suitelink Limited | Information & communication | 2026 |
| Sujash Consulting Limited | Professional & scientific | 2016 |
| Sukh Holdings Ltd | Real estate | 2024 |
| Sukira Ltd | Health & social care | 2014 |
| Suleman Legal Services Limited | Professional & scientific | 2021 |
| Suleyman BEY Ltd | Manufacturing | 2021 |
| Sultan Management Ltd | Real estate | 2020 |
| Sultan Portfolio Ltd | Real estate | 2020 |
| Sultana's Properties Ltd | Real estate | 2025 |
| Sumac Properties Limited | Real estate | 2000 |
| Sumad Plus Limited | Professional & scientific | 2025 |
| Sumc Ltd | Information & communication | 2025 |
| Summerdaze Limited | Other services | 2023 |
| Summerfields Developments Limited | Real estate | 2017 |
| Summerfields Homes Limited | Construction | 2017 |
| Summers & Co (MK) Ltd | Construction | 2026 |
| Summit & Stone Brokerage Ltd | Financial services | 2026 |
| Summit Aero Solutions Limited | Manufacturing | 2026 |
| Summit Campers Limited | Wholesale & retail | 2021 |
| Summit Consulting Limited | Professional & scientific | 2022 |
| Summit Financial Solutions Limited | Extraterritorial | 2001 |
| Summit Oak Logistics Ltd | Transport & logistics | 2026 |
| Summit Oak Ltd | Real estate | 2025 |
| Summit Publishing Limited | Information & communication | 1995 |