| DR RT Medical Services Ltd | Health & social care | 2024 |
| Dragon Energy Limited | Energy | 2004 |
| Dragon LNG Group Limited | Professional & scientific | 2004 |
| Dragon LNG Limited | Energy | 2002 |
| Dragon Systems Ltd | Construction | 2019 |
| Dragonfly Project Delivery Ltd. | Professional & scientific | 2015 |
| Dragons Breath Limited | Extraterritorial | 2008 |
| Dragons Rest Property Ltd | Hospitality | 2025 |
| Drive Clean Detailing Ltd | Wholesale & retail | 2023 |
| Dr`S R.B. Davies & C.B. Martin Limited | Health & social care | 2003 |
| Dyfed Electronics Limited | Wholesale & retail | 1981 |
| Dyfed Holdings Limited | Financial services | 2026 |
| E & E Carpentry Ltd | Real estate | 2018 |
| E J Evans & SON Limited | Transport & logistics | 2006 |
| East Berkshire Trading Limited | Wholesale & retail | 2015 |
| ECC Cleaning Services Ltd | Administrative & support | 2026 |
| Egnedol Bio-Energy Limited | Agriculture & fishing | 2015 |
| Egnedol Pembroke Eco-Power Limited | Energy | 2014 |
| Egnedol UK Limited | Professional & scientific | 2006 |
| Egnedol Wales Limited | Professional & scientific | 2014 |
| EJI Inspection & NDT Services Ltd | Professional & scientific | 2018 |
| EJL Property Sales Ltd | Real estate | 2026 |
| Electrifywales Limited | Construction | 2021 |
| Elements Gymnastics Academy Ltd | Arts & recreation | 2015 |
| Elite Electro Plating Ltd. | Manufacturing | 1998 |
| Ellajay Engineering Limited | Professional & scientific | 2016 |
| Elliots Hill Care Limited | Health & social care | 2009 |
| Energro Limited | Construction | 2026 |
| Enfield Projects Ltd | Real estate | 2026 |
| Enviroventure Waste Solutions Limited | Administrative & support | 2007 |
| EP Monumental Masons Ltd | Manufacturing | 2022 |
| European Tyre Investments Limited | Wholesale & retail | 2020 |
| Evamark Ltd | Hospitality | 2023 |
| Evan Rees (Dyfed) Limited | Wholesale & retail | 1978 |
| Eveling (Tuscan NO 31) Limited | Households | 2008 |
| Evens & Co Limited | Professional & scientific | 1992 |
| Events Flow Limited | Information & communication | 2019 |
| EVENTS4U Limited | Hospitality | 2025 |
| Evoque Estates Ltd | Real estate | 2017 |
| Ewjh Golf Limited | Wholesale & retail | 2016 |
| Exergie Limited | Professional & scientific | 2000 |
| Ezman Food Ltd | Hospitality | 2021 |
| Fair Deals Scaffolding Limited | Extraterritorial | 2015 |
| Famweld Limited | Manufacturing | 1981 |
| Femuk Limited | Professional & scientific | 2019 |
| Fire & Safety Products Ltd | Wholesale & retail | 2016 |
| First Rate Home Services Ltd | Construction | 2022 |
| First Skills Ltd | Other services | 2014 |
| Firwood Homes Limited | Manufacturing | 1993 |
| FJ Groundwork & Fencing Ltd | Construction | 2022 |
| Flecsishelf Limited | Manufacturing | 2023 |
| Flotech-Wales Ltd | Construction | 2025 |
| Flowers & Favours Limited | Wholesale & retail | 2009 |
| Food Safety Advice Service Limited | Hospitality | 2019 |
| Forrest Print Limited | Manufacturing | 2009 |
| Forrest Scaffolding & Roofing Limited | Construction | 2024 |
| Forward Global Markets Limited | Administrative & support | 2025 |
| Forward Thinking Business Limited | Administrative & support | 2004 |
| Freedom of Choice Limited | Construction | 2007 |
| Freemans (Milford Haven) Ltd | Wholesale & retail | 2011 |
| Freemans (Milford Haven) Properties Limited | Real estate | 2020 |
| Freshspace Interiors Limited | Construction | 2020 |
| FT Bouncy Castles Ltd | Arts & recreation | 2023 |
| Funtimes Entertainments Limited | Arts & recreation | 2015 |
| Fusion Installs Ltd | Construction | 2025 |
| Future GEN Care Ltd | Other services | 2024 |
| Future Generation Care Ltd | Other services | 2025 |
| G & E Fowke Limited | Agriculture & fishing | 2023 |
| Gaddarn Reach Management Company Limited | Real estate | 1988 |
| Gardening Gifts Co. Ltd | Wholesale & retail | 2025 |
| Gardner Tankage Consultancy Limited | Administrative & support | 2017 |
| Gareth Hughes (Motors) Limited | Wholesale & retail | 2021 |
| Gareth J Hughes (Motors) Limited | Wholesale & retail | 1982 |
| Gelli Marine Renewables Limited | Professional & scientific | 2016 |
| Gelli MOR Ltd | Health & social care | 2011 |
| Gemini Security & Training Ltd | Administrative & support | 2024 |
| Gemini Security Team Limited | Administrative & support | 2019 |
| Gemma Scourfield Limited | Professional & scientific | 2021 |
| GET Diggity Ltd | Financial services | 2024 |
| Gibby's Maintenance Services Ltd | Other services | 2026 |
| Global Energy Contracts Limited | Construction | 2016 |
| GMW Properties Limited | Real estate | 2020 |
| Go Greener Taxis Limited | Transport & logistics | 2018 |
| Go OUT With a Bang Competition Ltd | Arts & recreation | 2025 |
| Golden Fleece Online Limited | Wholesale & retail | 2018 |
| GP Construction Management Services Ltd | Construction | 2025 |
| Granicol Limited | Manufacturing | 2001 |
| Grass Roots Caravan and Glamping Ltd | Hospitality | 2022 |
| Greebur Ltd | Professional & scientific | 2024 |
| Greenacres Rescue Limited | Professional & scientific | 2016 |
| Griffiths Brothers Ltd | Agriculture & fishing | 2026 |
| Griffiths Property Maintenance Ltd | Construction | 2016 |
| GRS Motor Group Ltd | Administrative & support | 2016 |
| GRS Motor Holdings Ltd | Administrative & support | 2021 |
| GSD Engineering Limited | Construction | 2013 |
| H & P Pembrokeshire Ltd | Hospitality | 2025 |
| H2C02 Ltd | Energy | 2025 |
| Hadleys Plastering & Building Services Limited | Construction | 2023 |
| Hafan Housing Limited | Real estate | 2026 |
| Hakin Point Management Ltd | Real estate | 2022 |