| Innvopack Holdings Limited | Financial services | 2023 |
| Inovarex Group Ltd | Wholesale & retail | 2025 |
| Inrose Limited | Wholesale & retail | 2026 |
| Insideline Support CIC | Information & communication | 2025 |
| Insider Brands Limited | Professional & scientific | 2022 |
| Insight Health and Therapy Ltd | Health & social care | 2021 |
| Insight Metrics Ltd | Professional & scientific | 2023 |
| Inspire Parfums LLP | | 2025 |
| Inspired by Wonder Ltd | Wholesale & retail | 2022 |
| Inspired Remote Assistance Ltd | Information & communication | 2025 |
| Inspirehubb Limited | Professional & scientific | 2023 |
| Integralis Solutions Limited | Construction | 2025 |
| Integrated Transport Services Limited | Transport & logistics | 2023 |
| Integrative Psychotherapy Centre Ltd | Health & social care | 2026 |
| Integritas Tax Recruitment Limited | Professional & scientific | 2025 |
| Intel Tuition Ltd | Education | 2024 |
| Intelico Limited | Information & communication | 2012 |
| Intellectual Cookie Limited | Financial services | 2024 |
| Intels Hub Ltd | Information & communication | 2026 |
| Intentional Team Coaching Limited | Professional & scientific | 2022 |
| Inter Property Group Limited | Real estate | 2025 |
| Interaction Online Limited | Information & communication | 2010 |
| Interactive Century Culture Co., Ltd | Wholesale & retail | 2026 |
| Interactive Dating & Entertainment Limited | Information & communication | 2002 |
| Interactive Industries Ltd | Wholesale & retail | 2024 |
| Interactive London Ltd | Other services | 2024 |
| Interboard L.P. | | 2017 |
| Intergrated Business Support Limited | Administrative & support | 2025 |
| International Business Analysts Limited | Information & communication | 2025 |
| International Careers Network Ltd | Education | 2024 |
| International Culture & Education Center Ltd | Information & communication | 2024 |
| International Education and Migration Consultants Ltd | Professional & scientific | 2019 |
| International LAB for Interdisciplinary Research | Professional & scientific | 2024 |
| International Legal Advisers Limited | Professional & scientific | 2007 |
| International Star Media Ltd | Information & communication | 2025 |
| Internet Software Ltd | Information & communication | 2009 |
| Intersect Software Ltd | Information & communication | 2023 |
| Interstock Trade Limited | Wholesale & retail | 2026 |
| Intrachartered Ltd. | Administrative & support | 2014 |
| Intranex Limited | Information & communication | 2024 |
| Introduced Clothing Ltd | Wholesale & retail | 2025 |
| Intta Studio Ltd | Wholesale & retail | 2025 |
| Inubiz Marketing Ltd | Information & communication | 2026 |
| INUV8 Limited | Professional & scientific | 2024 |
| Inveniumx Limited | Professional & scientific | 2025 |
| Inventio Ltd | Professional & scientific | 2025 |
| Inverway Ltd | Professional & scientific | 2024 |
| Invest Station Group Ltd | Education | 2025 |
| Investment Catalyst Limited | Financial services | 2024 |
| Investment Structures Limited | Real estate | 2019 |
| Invictus Emergency Response Ltd | Health & social care | 2026 |
| Invinsive Ltd | Wholesale & retail | 2021 |
| Invision Consulting Limited | Professional & scientific | 2025 |
| Invy Ltd | Information & communication | 2026 |
| Inyourroots Ltd | Information & communication | 2026 |
| ION Tech Engineering Ltd | Manufacturing | 2024 |
| Ionix Limited | Information & communication | 2005 |
| Ioss Consulting Ltd | Professional & scientific | 2024 |
| Iotclass CIC | Education | 2026 |
| Ipeak Academy Ltd | Wholesale & retail | 2023 |
| Irie Social Care Ltd | Health & social care | 2023 |
| IRM13 Ltd | Wholesale & retail | 2026 |
| Iron Bridge Gear Ltd | Wholesale & retail | 2025 |
| Iron Stable Ltd | Information & communication | 2026 |
| Iron&Iron Marine Limited | Professional & scientific | 2024 |
| Ironbike Ltd | Manufacturing | 2025 |
| Ironixpay Ltd | Information & communication | 2026 |
| Ironpulse Technologies Ltd | Information & communication | 2025 |
| Isabel Straw Consulting Ltd | Professional & scientific | 2025 |
| Isadora Jewellery Ltd | Manufacturing | 2020 |
| Isar Green Ltd | Construction | 2019 |
| Isaro Jewelry Trading Limited | Wholesale & retail | 2025 |
| Iscan Global Limited | Wholesale & retail | 2025 |
| Iseco Limited | Wholesale & retail | 2026 |
| Isha’S Events Ltd | Arts & recreation | 2026 |
| Ishe Global Limited | Wholesale & retail | 2025 |
| Isigim Ltd | Wholesale & retail | 2023 |
| ISJ Accounting Limited | Administrative & support | 2018 |
| Isla NF Limited | Professional & scientific | 2020 |
| Island Wool Ltd | Manufacturing | 2023 |
| Islands Contracting Ltd | Construction | 2023 |
| Islands Food Drinks Vibes Ltd | Hospitality | 2023 |
| Isthistrue Ltd | Information & communication | 2025 |
| IT Infrastructure Implementation Services Ltd | Information & communication | 2025 |
| IT Labs Inc Ltd | Information & communication | 2025 |
| It's NOT Even Limited | Professional & scientific | 2026 |
| ITC Solutions Ltd | Information & communication | 2015 |
| Itchen Group Holdings Limited | Professional & scientific | 2022 |
| Itera Logic Ltd | Information & communication | 2026 |
| ITS Elevate Marketing Ltd | Professional & scientific | 2025 |
| Iuagd Lpjg Limited | Wholesale & retail | 2025 |
| Ivanovs DEV Ltd | Wholesale & retail | 2025 |
| Iverys Ltd | Professional & scientific | 2025 |
| Ivology Ltd | Health & social care | 2025 |
| Ivor & Co Limited | Real estate | 2023 |
| IVY Fashion Limited | Wholesale & retail | 2023 |
| IWM Atomic Ltd | Information & communication | 2025 |
| IY Interiors Limited | Real estate | 2021 |
| Iyaad Applications Technologies Trading Limited | Wholesale & retail | 2026 |
| Iyam Limited | Information & communication | 2017 |