| Dunamis (U.K.) Ltd | Wholesale & retail | 2025 |
| Dundee Software Limited | Information & communication | 2024 |
| Dunscombe Ltd | Professional & scientific | 2018 |
| Duosky Commerce Ltd | Wholesale & retail | 2025 |
| Durdle Moon Records Limited | Arts & recreation | 2020 |
| Durinox & Co. Limited | Wholesale & retail | 2025 |
| Durmakos Limited | Professional & scientific | 2025 |
| Dutch Posture Solutions Ltd | Wholesale & retail | 2025 |
| Duxford Restoration Limited | Manufacturing | 2024 |
| Dwelio Estates Limited | Real estate | 2026 |
| DX Training Ltd | Education | 2025 |
| DXK Global Consulting Ltd | Professional & scientific | 2025 |
| Dycon Limited | Information & communication | 2024 |
| Dynamic Agile Services Limited | Information & communication | 2011 |
| Dynamic Plastic Solutions Ltd | Manufacturing | 2023 |
| Dynamicsy Ltd | Wholesale & retail | 2023 |
| Dynamite 74 Ltd | Wholesale & retail | 2025 |
| Dynamix-Uk Ltd | Professional & scientific | 2026 |
| Dynar Ltd | Wholesale & retail | 2025 |
| Dynatomics Ltd | Information & communication | 2025 |
| Dyneals Ltd | Wholesale & retail | 2024 |
| Dyno Fitness Limited | Information & communication | 2025 |
| DYS Tech Solutions Ltd | Wholesale & retail | 2025 |
| E & Alain Worldwide Group Limited | Administrative & support | 2020 |
| E G Marketing Ltd | Professional & scientific | 2026 |
| E Global Doctors (UK) LLP | | 2023 |
| E&C Group Ltd | Wholesale & retail | 2022 |
| E&D Inventory Ltd | Wholesale & retail | 2023 |
| E&R Motor Group Ltd | Wholesale & retail | 2025 |
| E-Motion Physiotherapy Ltd | Health & social care | 2023 |
| E-Native Ltd | Education | 2020 |
| E3 Signature Catering Ltd | Wholesale & retail | 2025 |
| E9 Consulting Ltd | Administrative & support | 2022 |
| EA Autos Limited | Wholesale & retail | 2024 |
| EA Market Limited | Wholesale & retail | 2025 |
| EA Marketing & Consultants Ltd | Administrative & support | 2025 |
| Eager OWL Ltd | Education | 2025 |
| Eagle Consultancy Ltd | Professional & scientific | 2026 |
| Eagle Imports and Exports Ltd | Wholesale & retail | 2022 |
| Eagle Likes Ltd | Administrative & support | 2022 |
| Eagle Vision Asset Management Ltd | Administrative & support | 2022 |
| Eagle-Hill Capital Group Limited | Financial services | 2025 |
| Eaglecreed Limited | Information & communication | 2024 |
| Eahworld Ltd | Administrative & support | 2018 |
| Earl Grove Limited | Manufacturing | 2025 |
| Ears Property Limited | Real estate | 2023 |
| Earth Digital Limited | Information & communication | 2009 |
| Earth Origins Ltd | Wholesale & retail | 2020 |
| Earth Woven Ltd | Manufacturing | 2026 |
| East Anglia Air Conditioning Ltd | Construction | 2026 |
| East ARC Ltd | Wholesale & retail | 2025 |
| East Blue Events Ltd | Administrative & support | 2026 |
| East Coast Media Ltd | Transport & logistics | 2019 |
| East Grinstead Womens Share CIC | Health & social care | 2025 |
| East Midlands Collector Car Storage Ltd | Transport & logistics | 2025 |
| Eastacre Estates Limited | Real estate | 2002 |
| Eastment Ltd | Wholesale & retail | 2024 |
| Eastnature Ltd | Wholesale & retail | 2024 |
| Easton Wealth Ltd | Financial services | 2026 |
| Easy Bits Limited | Information & communication | 2012 |
| Easy Traders Ltd | Wholesale & retail | 2026 |
| Easy Way Mobility Group Ltd | Wholesale & retail | 2025 |
| Easylux Limited | Wholesale & retail | 2025 |
| Easysetup International Consulting Services Ltd | Wholesale & retail | 2024 |
| Eatnoshed Ltd | Manufacturing | 2024 |
| Ebersol Limited | Real estate | 2023 |
| Ecf(Uk) Limited | Transport & logistics | 2022 |
| Echo Services Ltd | Health & social care | 2026 |
| ECK Media Limited | Other services | 2022 |
| Eclal Global Ltd | Wholesale & retail | 2025 |
| Eclare Consultancy Ltd | Professional & scientific | 2024 |
| Eclipse Home Improvements 2026 Limited | Construction | 2026 |
| Eclipt Ltd | Professional & scientific | 2025 |
| Eco Luxury Cleaning Ltd | Administrative & support | 2024 |
| Ecoaite Ltd | Wholesale & retail | 2025 |
| Ecoimpex LLP | | 2004 |
| Ecoline Import PC | | 2019 |
| Ecom Activities Ltd | Wholesale & retail | 2025 |
| Ecom ELM Ltd | Wholesale & retail | 2025 |
| Ecom Express INT Ltd | Wholesale & retail | 2024 |
| Ecom Forse Ltd | Wholesale & retail | 2026 |
| Ecom Mart INT Limited | Wholesale & retail | 2024 |
| Ecom Prtal Ltd | Wholesale & retail | 2025 |
| Ecom Ship Ltd | Transport & logistics | 2025 |
| Ecom With DE Helium Private Limited | Wholesale & retail | 2025 |
| Ecomaj Consulting Ltd | Professional & scientific | 2024 |
| Ecomfind Inc Ltd | Wholesale & retail | 2025 |
| Ecomizi Ltd | Wholesale & retail | 2025 |
| Ecomm Goods Limited | Wholesale & retail | 2024 |
| Ecommerce Corporelle Ltd | Wholesale & retail | 2026 |
| Ecomverce Agency Ltd | Wholesale & retail | 2024 |
| Ecoteo Limited | Construction | 2021 |
| Ecoworm Limited | Manufacturing | 2012 |
| ECR Minerals PLC | Mining & quarrying | 2004 |
| Ecutos Limited | Wholesale & retail | 2019 |
| ED & Edge Limited | Information & communication | 2013 |
| ED AML Solutions Ltd | Professional & scientific | 2025 |
| Eden Chaser Ltd | Extraterritorial | 2011 |
| Eden Naturelle (by Kayevirtue) Ltd | Professional & scientific | 2021 |
| Eden of London Ltd | Administrative & support | 2017 |