| Rialto Labs Ltd | Information & communication | 2023 |
| Richard Tree (Bookkeeping) Limited | Professional & scientific | 2002 |
| Ridgeline Aviation Ltd | Transport & logistics | 2020 |
| Riverside Landscapes Limited | Construction | 2020 |
| RJ Rider Limited | Professional & scientific | 2013 |
| RKZ Limited | Professional & scientific | 2005 |
| Roar.Dog Ltd | Wholesale & retail | 2024 |
| Robot Brands Limited | Wholesale & retail | 2005 |
| Rock 'N Shards Limited | Manufacturing | 2019 |
| Rosebok Limited | Construction | 2021 |
| Rother Valley Together | Health & social care | 2011 |
| Rotherfield Motor Company Limited | Wholesale & retail | 2018 |
| Rough House Farms Limited | Agriculture & fishing | 1985 |
| Rough House Hire Ltd | Administrative & support | 2026 |
| Routemastr Technology Ltd | Information & communication | 2012 |
| RS Equine Partners Ltd | Transport & logistics | 2024 |
| RS Food Development Ltd | Hospitality | 2019 |
| Rummil Limited | Manufacturing | 2012 |
| Ryarsh Cars Limited | Wholesale & retail | 2018 |
| S B W Accounting Ltd | Professional & scientific | 2020 |
| S&A Hospitality Ltd | Hospitality | 2021 |
| Sapience Consulting Europe Limited | Professional & scientific | 2021 |
| Sapore Phil Ltd | Hospitality | 2025 |
| Satch Consultants Limited | Professional & scientific | 2012 |
| Satch Limited | Extraterritorial | 2013 |
| Scenic Risk Services Ltd. | Financial services | 2016 |
| Scentimental Limited | Wholesale & retail | 1997 |
| Schneider Form UK Ltd | Manufacturing | 2001 |
| Screen Glue Limited | Information & communication | 2013 |
| Sculpture Studio Limited | Manufacturing | 2002 |
| Seasoned Logs Limited | Agriculture & fishing | 2014 |
| Second Timbermill Court Management Company Limited(The) | Real estate | 1985 |
| Selcott Limited | Real estate | 1997 |
| Seymour Sales Training Consultancy Limited | Education | 2006 |
| Shard Fire Solutions Ltd | Construction | 2025 |
| Sharm Limited | Professional & scientific | 2004 |
| Sharpecom Limited | Professional & scientific | 2008 |
| Shoredome Limited | Real estate | 2010 |
| Shotter and Voice Limited | Construction | 2016 |
| Signet & Swan Holdings Limited | Financial services | 2024 |
| Silvertreekitchen Ltd | Manufacturing | 2026 |
| Simon Barnard Consultancy Services Limited | Information & communication | 2011 |
| Simplify Stuff Ltd | Other services | 2017 |
| Sitp Limited | Information & communication | 2026 |
| SJA Associates (London) Ltd | Information & communication | 2016 |
| SJC Business Advisers Limited | Professional & scientific | 2026 |
| SJS Groundworks Ltd | Construction | 2019 |
| Sjtw Consulting Limited | Professional & scientific | 2018 |
| Skillgate Limited | Information & communication | 1998 |
| Skinner Holden Property Advisors Limited | Real estate | 2016 |
| Solar Energy Services Ltd | Energy | 2021 |
| Sophisticated Hair Ltd | Other services | 2023 |
| South Downs Commercial Operations Limited | Hospitality | 2021 |
| South Downs Consulting Limited | Professional & scientific | 2026 |
| South Downs Embroidery Limited | Manufacturing | 2011 |
| South Downs Marquees Ltd | Hospitality | 2012 |
| South Downs National Park Trust | Other services | 2017 |
| South Heath Pathology Limited | Professional & scientific | 2019 |
| South Oak Developments Limited | Construction | 2005 |
| South Oak Homes Limited | Construction | 2019 |
| Southdown Property Solutions Limited | Real estate | 2018 |
| Southdown Shepherds Huts Limited | Administrative & support | 2016 |
| Southdowns Private Healthcare Limited | Health & social care | 2011 |
| Soxley Shaw Ltd | Professional & scientific | 2015 |
| Special Envoy Services Limited | Wholesale & retail | 2010 |
| Sports Partners International Limited | Administrative & support | 2018 |
| Sports Partners Travel and Logistics Limited | Transport & logistics | 2021 |
| Stanley Acrylics Ltd | Manufacturing | 2020 |
| Stanley Plastics Limited | Manufacturing | 1962 |
| Steelpods (Van Conversions) LLP | | 2020 |
| Striding Aitch Limited | Financial services | 2024 |
| Strudwick Scaffolding Ltd | Construction | 2017 |
| Stubbington Properties Ltd | Real estate | 2021 |
| Suescript Limited | Information & communication | 2009 |
| Sunwell Systems Ltd | Energy | 2009 |
| Superyacht Advisory Limited | Professional & scientific | 2020 |
| Supporters of Evelina London Ltd | Health & social care | 2018 |
| Sussex Enduro & Motocross Services Ltd | Wholesale & retail | 2023 |
| Sussex Standard Ltd | Financial services | 2021 |
| Tableswitch Limited | Real estate | 2005 |
| Take 10 Publishing Ltd | Professional & scientific | 2003 |
| Talismanics Limited | Professional & scientific | 2019 |
| Tamzin Lillywhite Limited | Manufacturing | 2018 |
| TBG Holdings Ltd | Administrative & support | 2021 |
| Terra Firma Auctions Ltd | Real estate | 2026 |
| THE Blackdown Partnership Limited | Professional & scientific | 2008 |
| THE Bricklayers Arms Midhurst Ltd | Hospitality | 2025 |
| THE Canape Collection Limited | Hospitality | 2001 |
| THE Chocolate Garage Limited | Education | 2022 |
| THE Fine Dining Table Ltd | Hospitality | 2026 |
| THE Freeboard Group Limited | Hospitality | 2020 |
| THE Gatehouse Management Company (Midhurst) Limited | Households | 1990 |
| THE Haven Beauty Room Ltd | Other services | 2023 |
| THE Home Service (Care Agency) Ltd | Health & social care | 2000 |
| THE Ideal Press Ltd | Professional & scientific | 2016 |
| THE Kilted KEG Limited | Hospitality | 2024 |
| THE Midhurst Bakery Limited | Wholesale & retail | 2014 |
| THE Midhurst Museum Tea Rooms Limited | Hospitality | 2019 |
| THE Old Courthouse Midhurst Limited | Households | 2022 |
| THE Really Regenerative Centre CIC | Administrative & support | 2019 |