| RJB Engineering Services (NE) Limited | Professional & scientific | 2018 |
| RJB International Limited | Administrative & support | 2017 |
| Rjih Surveying Limited | Professional & scientific | 2024 |
| RJL Surveying Ltd | Professional & scientific | 2012 |
| RJO Electrical Limited Limited | Extraterritorial | 2025 |
| RJS Social Care Limited | Professional & scientific | 2025 |
| RK Construction and Sons Ltd | Construction | 2026 |
| RK Instrument Services Ltd | Professional & scientific | 2025 |
| RK Lettings Ltd | Real estate | 2024 |
| RK Ventures NE Limited | Professional & scientific | 2025 |
| RKJ Group Limited | Wholesale & retail | 2020 |
| RL Comms Ltd | Information & communication | 2019 |
| RLF Technical Services Limited | Construction | 2025 |
| RLG Global Limited | Professional & scientific | 2015 |
| RLP Financial Limited | Financial services | 2019 |
| RLP Hospitality Consultancy Group Limited | Hospitality | 2026 |
| RLP Inspection Limited | Professional & scientific | 2022 |
| RLP Software Limited | Hospitality | 2026 |
| RM Car Wash Ltd | Administrative & support | 2021 |
| RM Instrument Ltd | Professional & scientific | 2023 |
| RM Physiotherapy Ltd | Health & social care | 2023 |
| RM Plumbing & Heating NE Limited | Construction | 2024 |
| RMB Process Limited | Professional & scientific | 2008 |
| RMD Rental Properties Ltd | Real estate | 2025 |
| RMM Site Services Limited | Professional & scientific | 2007 |
| RMM Technical Services Limited | Professional & scientific | 2023 |
| RN Consultancy Services Ltd | Extraterritorial | 2015 |
| RN IT Consulting Limited | Information & communication | 2014 |
| Rnet Ltd | Extraterritorial | 2021 |
| RNK Transport Limited | Transport & logistics | 2017 |
| Roaa Ltd | Real estate | 2017 |
| ROAD2RX Functional Fitness Ltd | Arts & recreation | 2022 |
| Robbb Limited | Manufacturing | 2026 |
| Robert Miller Financial Management Limited | Professional & scientific | 2000 |
| Robert Sandham Paving Contractor Ltd | Construction | 2013 |
| Roberto Cleaning 25 Ltd | Administrative & support | 2025 |
| Robertson NDT Inspection Ltd | Professional & scientific | 2022 |
| Robinson Enterprises Limited | Professional & scientific | 2011 |
| Robinson Mechanical Services Ltd | Manufacturing | 2023 |
| Robinson Site Solutions Ltd | Construction | 2025 |
| Robohive Ltd | Education | 2022 |
| Robru 1 Limited | Real estate | 2024 |
| Robson & SON Builders Limited | Construction | 2022 |
| Robson DC Solutions Limited | Professional & scientific | 2024 |
| Robson Leisure Limited | Hospitality | 2022 |
| Robsons Leisure Ltd | Hospitality | 2015 |
| Roche Engineering Ltd | Manufacturing | 2020 |
| Rock Antics Middlesbrough Ltd | Arts & recreation | 2011 |
| Rock Paving & Landscapes Ltd | Administrative & support | 2018 |
| Rockcliffe Elderwood Ltd | Administrative & support | 2025 |
| Rockcliffe Engineering Limited | Manufacturing | 1981 |
| Rockdale Estates Ltd. | Construction | 2015 |
| Rocket Dog Creative Ltd | Information & communication | 2016 |
| Rocket Project Partners Ltd | Professional & scientific | 2024 |
| Rockliffe Construction Services (NE) Limited | Professional & scientific | 2011 |
| Rockwool Compliance Limited | Professional & scientific | 2026 |
| Rodlix Limited | Wholesale & retail | 2024 |
| Rogan Energy Infrastructure Ltd | Construction | 2026 |
| Rogers Bukasa Associates Ltd | Professional & scientific | 2019 |
| Rogue T Limited | Manufacturing | 2025 |
| Rohman Ltd | Professional & scientific | 2026 |
| ROJ Group Private Ltd | Wholesale & retail | 2026 |
| Rojac Investments Limited | Real estate | 2020 |
| ROK Bioconsulting Limited | Professional & scientific | 2015 |
| Rollershield Limited | Construction | 2012 |
| Rollout Brands Limited | Hospitality | 2026 |
| Roma Construction Solutions Limited | Construction | 2019 |
| Roma Lettings Limited | Real estate | 2019 |
| Roma Shop UK Ltd | Wholesale & retail | 2022 |
| Roman Leisure Limited | Hospitality | 2022 |
| Roman Road Car Sales Limited | Wholesale & retail | 1997 |
| Romangate Property Management Company Ltd | Households | 2020 |
| Romar Mechanics Ltd | Wholesale & retail | 2025 |
| Romie&Ronnie Housing Limited | Real estate | 2025 |
| Ronpolsafetysoultions Ltd | Professional & scientific | 2024 |
| ROO Properties Limited | Real estate | 2025 |
| Rookwoods Rose Ltd | Real estate | 2026 |
| Room for Design Limited | Professional & scientific | 2014 |
| Rooms at Teesside Limited | Households | 2021 |
| Rooms of Stokesley Limited | Other services | 2004 |
| Roosters Fried Chicken Stockton Limited | Hospitality | 2024 |
| Roots Residential Building Surveyors Ltd | Construction | 2022 |
| Rope Access MAN Power UK Ltd | Construction | 2017 |
| Ropetech Access Ltd | Manufacturing | 2024 |
| Rore Painting Services Ltd | Construction | 2019 |
| Rosaleigh Ltd | Information & communication | 2023 |
| Rosant Healthcare Ltd | Public administration | 2023 |
| Rose Beautician Ltd | Other services | 2020 |
| Rose Commercial Limited | Real estate | 2013 |
| Rose Cottage Construction Ltd | Construction | 2020 |
| Rose Funerals Limited | Other services | 2013 |
| Rose Wind Services Ltd | Administrative & support | 2026 |
| Roseberry Financial Limited | Financial services | 2008 |
| Roseberry Gardens Management Company Limited | Households | 2025 |
| Roseberry Newhouse Ltd | Real estate | 2004 |
| Roseberry Pet Crematorium Ltd | Other services | 2024 |
| Roseberry Property Holdings Ltd | Construction | 2019 |
| Roseberry River Limited | Wholesale & retail | 2024 |
| Roseberry Structural Limited | Administrative & support | 2013 |
| Roseberry View Ltd | Hospitality | 2026 |