| Woodhurst Management Limited | Households | 1985 |
| Woods Capital Ltd | Financial services | 2017 |
| Woods Group (Surrey) Ltd | Real estate | 2018 |
| World Crew Services LLP | | 2013 |
| Worx Software Limited | Information & communication | 2020 |
| Wottz Ltd | Manufacturing | 2021 |
| Wren General Merchants Limited | Real estate | 1961 |
| Wrigley Foster Media Direct Limited | Professional & scientific | 1992 |
| Write of Reply Ltd | Professional & scientific | 2025 |
| WSA Community Consultants Limited | Health & social care | 2002 |
| Wycombe Gymnastics Academy Limited | Arts & recreation | 2012 |
| Wycombe Squash and Racketball Club Ltd | Arts & recreation | 1973 |
| Wycombe Women's AID Limited | Other services | 1988 |
| Wyfold Investments Unlimited | Financial services | 2015 |
| Wylva Properties Limited | Financial services | 2021 |
| Wylva Trading Limited | Administrative & support | 2009 |
| Xcm-Ai Ltd | Information & communication | 2026 |
| Xlcare Limited | Health & social care | 2005 |
| XV Solutions Limited | Administrative & support | 2014 |
| Yarranabbe Limited | Real estate | 2026 |
| Yorkshire & North East Hockey Limited | Arts & recreation | 2021 |
| Yorkshires Cleaning Services Ltd | Administrative & support | 2011 |
| Youmed Limited | Wholesale & retail | 2015 |
| Your Body Workshop Marlow Ltd | Other services | 2022 |
| Your Dream Car Ltd | Wholesale & retail | 2023 |
| Your Lovely Garden Limited | Administrative & support | 2014 |
| Your Voice Assocs Limited | Professional & scientific | 2026 |
| Yourultimatehealth Limited | Health & social care | 2023 |
| YPK Consutling Services Ltd | Information & communication | 2024 |
| ZAK1DESIGN Ltd | Construction | 2022 |
| Zam-Zam Care Service Limited | Health & social care | 2019 |
| Zentronix AI Limited | Information & communication | 2025 |
| Zest Drycleaners & Laundry Ltd | Other services | 2025 |
| Zeus Jedi Ltd | Financial services | 2020 |
| Zing Productions Limited | Information & communication | 2007 |
| ZKO Creative Ltd | Professional & scientific | 2022 |
| Zorin Energy Ltd | Mining & quarrying | 2025 |