| Riva Ridge Ltd | Information & communication | 2023 |
| Riverwoods Consulting Ltd | Professional & scientific | 2018 |
| Riverwoods Drive Management Company Limited | Extraterritorial | 2011 |
| RJM Criminal Defence Ltd | Professional & scientific | 2023 |
| RJS Strategy Ltd | Professional & scientific | 2017 |
| RKF Consult Limited | Construction | 2006 |
| RMB Chelsea Limited | Construction | 2013 |
| RMB Elpin Ltd | Construction | 2019 |
| ROB Cole PM Services Ltd | Information & communication | 2013 |
| ROB Eagle Limited | Professional & scientific | 2000 |
| Roberts Riley BI Ltd | Financial services | 2013 |
| Robicheaux Ltd | Wholesale & retail | 2026 |
| Robinhill Property Management Company Limited | Households | 1993 |
| Rock Asset Management Limited | Real estate | 2002 |
| Rock Capital Partners Limited | Construction | 2025 |
| Rock Co. Capital Limited | Real estate | 2014 |
| Rock Co. Limited | Real estate | 2014 |
| Rock Co. Properties Limited | Real estate | 2012 |
| Rocket Fuel Incorporated Ltd | Professional & scientific | 2023 |
| Roger Frier & Associates Limited | Professional & scientific | 1987 |
| Rolling Stock Limited | Information & communication | 1988 |
| Romenpost Limited | Information & communication | 1999 |
| Rootsy Ltd | Wholesale & retail | 2025 |
| Rosalind Barrance Limited | Professional & scientific | 2015 |
| Rosemary Place (Marlow) Limited | Households | 2006 |
| Rounding Corners Ltd | Professional & scientific | 2020 |
| Rowjam Consulting Limited | Professional & scientific | 2014 |
| RRM Lettings Ltd | Real estate | 2024 |
| RS Elite Homes Ltd | Real estate | 2026 |
| RS REG Consultancy Limited | Professional & scientific | 2022 |
| Rubik's Brand Limited | Professional & scientific | 2013 |
| Ruby Pseudo Consulting Ltd | Professional & scientific | 2007 |
| Rucola Limited | Hospitality | 1998 |
| Runners' Retreat Marlow Limited | Wholesale & retail | 2011 |
| Ruskells Ltd | Professional & scientific | 2006 |
| Russetts Consultancy Limited | Real estate | 2017 |
| Rust Inc Limited | Other services | 2021 |
| RWA Capital Limited | Financial services | 2023 |
| Ryan Pritchard Consulting Ltd | Information & communication | 2020 |
| S & B Hair Limited | Other services | 2020 |
| S Cleared Limited | Information & communication | 2026 |
| S N Property Developments Ltd | Real estate | 2018 |
| S Walton Associates Ltd | Professional & scientific | 2024 |
| S.A.E.M Construction Ltd | Construction | 2021 |
| S.J. Cheshire Limited | Wholesale & retail | 1988 |
| S3 Mercury SUB Ltd | Information & communication | 2024 |
| S3 Topco UK Ltd | Information & communication | 2024 |
| SA Pharma Global Ltd | Wholesale & retail | 2025 |
| Saarek Skin Limited | Health & social care | 2024 |
| Sagittarius Intellectual Property LLP | | 2009 |
| Saikamalam Consulting UK Ltd | Information & communication | 2011 |
| Saint Edwards Estates Limited | Construction | 2014 |
| Saint London Studios Ltd | Professional & scientific | 2025 |
| Sako Ltd | Other services | 2011 |
| Salamanca Endo UK Ltd | Administrative & support | 2026 |
| Salcombe Tea Company Ltd | Manufacturing | 2025 |
| Salon Ambience Limited | Wholesale & retail | 1998 |
| Saltee Skincare Limited | Wholesale & retail | 2018 |
| SAM I AM Ltd | Information & communication | 2024 |
| Samantha Lines Footwear Limited | Wholesale & retail | 2022 |
| Samay (Ckaf) Ltd | Hospitality | 2016 |
| Samay (Yogi) Ltd | Hospitality | 2026 |
| Sanctuary Sound Limited | Administrative & support | 2004 |
| Sandhurst Asset Management Ltd | Real estate | 2026 |
| Sandpipers Place (Cookham) Management Company Limited | Households | 2007 |
| Sandy Bryant Limited | Households | 1976 |
| Sandy Royden Consulting Ltd | Professional & scientific | 2023 |
| Sandyman-Investments Ltd | Wholesale & retail | 2021 |
| Sanha UK Ltd | Administrative & support | 2004 |
| Sara Agar Interiors Ltd | Professional & scientific | 2005 |
| Sara Hughes Home Ltd | Wholesale & retail | 2012 |
| Sarah Grace London Ltd | Manufacturing | 2016 |
| Sarah Mannerings Ltd | Professional & scientific | 2017 |
| Sarthe Cars Ltd | Manufacturing | 2019 |
| SAS Software Limited | Information & communication | 1977 |
| Sashed Ltd | Construction | 2015 |
| Saturn Hotels Limited | Administrative & support | 2025 |
| Sauktax Ltd | Professional & scientific | 2020 |
| Savage & Savage Property Ltd | Real estate | 2023 |
| Savage Reputation Limited | Professional & scientific | 2025 |
| Savage Residential Limited | Real estate | 2016 |
| Save Marlow's Greenbelt Limited | Other services | 2023 |
| Sbrm Property Ltd | Real estate | 2023 |
| Scamp and Dude Limited | Wholesale & retail | 2016 |
| Scaramanga Holdings Ltd | Financial services | 2020 |
| Sceptre Gate Management Company Limited | Households | 2014 |
| Schwabe Pharma (UK) Limited | Health & social care | 2005 |
| Schwing Limited | Manufacturing | 2006 |
| Schwing Stetter (UK) Ltd | Manufacturing | 1946 |
| Scorpio Electrical Limited | Construction | 1997 |
| Scorpio IP Limited | Administrative & support | 2002 |
| Scott & Chase Hair & Beauty Limited | Other services | 2020 |
| Scott & Chase Limited | Other services | 2020 |
| Scottwell Properties Ltd | Real estate | 2025 |
| SD Aviation Aircraft Interior Recycling Limited | Water & waste | 2014 |
| SD Carpentry & Building Ltd | Construction | 2021 |
| Seacliff Consulting Ltd | Professional & scientific | 2022 |
| Seagate Systems (UK) Limited | Information & communication | 1995 |
| Sean Antony Hairdressing Limited | Real estate | 2017 |
| Sean Wheeler Consulting Ltd | Professional & scientific | 2020 |