| D & R Furnishers Limited | Wholesale & retail | 1964 |
| D G Rhodes Groundworks Limited | Construction | 2007 |
| D.L. Lemon (Wilton) Limited | Agriculture & fishing | 1961 |
| Damerstown Limited | Professional & scientific | 2020 |
| DAN Knight Consulting Limited | Professional & scientific | 2024 |
| Data Analytic Solutions Ltd | Information & communication | 2011 |
| Dataplex Datacentres (UK) Limited | Information & communication | 2015 |
| David and Goliath Limited | Professional & scientific | 2009 |
| David Cullen Ltd | Professional & scientific | 2016 |
| David M Hall Limited | Construction | 2004 |
| David Osborne Asset Management LLP | | 2017 |
| Davies Telecoms Limited | Information & communication | 2010 |
| Day 1 People Holdings Limited | Professional & scientific | 2024 |
| Day 1 People Limited | Professional & scientific | 2017 |
| Daylee Transport Ltd | Transport & logistics | 2025 |
| DB Microbiology Ltd | Administrative & support | 2017 |
| DC Gate Solutions Ltd | Construction | 2019 |
| DCM Media Ltd | Information & communication | 2022 |
| Deanns Limited | Construction | 1986 |
| Debeukelaer-Wambersie Ltd | Professional & scientific | 2006 |
| Defacto Learning Solutions Limited | Professional & scientific | 2017 |
| Depart Ltd | Transport & logistics | 2019 |
| Department 83 Limited | Agriculture & fishing | 2001 |
| Descendant Audio and AV Ltd | Wholesale & retail | 2025 |
| Design 360 Ltd | Wholesale & retail | 2005 |
| Design 360 Properties Ltd | Real estate | 2023 |
| Design Modelling Services Ltd | Professional & scientific | 2004 |
| Detail Car Care Limited | Wholesale & retail | 2021 |
| Devil's DEN (Wiltshire) Limited | Households | 2021 |
| Devotion Ecumenical Youth Project Ltd | Other services | 2022 |
| Dexterium Limited | Information & communication | 2015 |
| DGR Law Limited | Extraterritorial | 2015 |
| Dgxc Limited | Information & communication | 2015 |
| DH Mining Advisory Services Limited | Administrative & support | 2012 |
| Dhillon Traders Ltd | Wholesale & retail | 2010 |
| Diamond Equestrian Ltd | Arts & recreation | 2019 |
| Diamond International Transport Ltd | Transport & logistics | 2019 |
| Dickle Ltd | Hospitality | 2014 |
| Diego Velazquez Limited | Agriculture & fishing | 2026 |
| Diego Velazquez Stallion Limited | Information & communication | 2010 |
| DIG Club Ltd | Wholesale & retail | 2021 |
| Digital Motor Works Limited | Wholesale & retail | 2018 |
| Direct Wisdom UK Ltd | Health & social care | 2025 |
| DK Properties South West Limited | Construction | 2024 |
| DK Property Group Limited | Real estate | 2025 |
| Doctor Anna Ltd | Wholesale & retail | 2020 |
| Donald Scott Holdings Limited | Financial services | 2023 |
| Doris Archer Motorsport Limited | Administrative & support | 2024 |
| Dovetech Limited | Information & communication | 2012 |
| DQ Contracting Limited | Professional & scientific | 2014 |
| Drug Delivery Insights Limited | Professional & scientific | 2025 |
| DSA Advisory Limited | Professional & scientific | 2018 |
| DSA Taxation Limited | Extraterritorial | 2010 |
| Duckworths Arboriculture Limited | Professional & scientific | 2022 |
| Duncan Morris Solicitors Ltd | Professional & scientific | 2009 |
| Dunlin Property Ltd | Real estate | 2020 |
| DWL Landscaping Ltd | Administrative & support | 2016 |
| E & a G Stratton Limited | Agriculture & fishing | 2011 |
| E & C Engineering Ltd | Construction | 2017 |
| E J Wicks Limited | Wholesale & retail | 2013 |
| E P Cambridge UK Limited | Agriculture & fishing | 2004 |
| E-Wave Research Ltd | Administrative & support | 2021 |
| E.G. Homes Ltd | Real estate | 2019 |
| Earthlime Limited | Mining & quarrying | 2013 |
| Earthline Exchange Limited | Professional & scientific | 2014 |
| Earthline Holdings Limited | Professional & scientific | 2004 |
| Earthline Limited | Mining & quarrying | 1990 |
| East Kennet PCN Ltd | Health & social care | 2023 |
| East Leaze Farm Limited | Arts & recreation | 2020 |
| Eastcourt Advisory Limited | Professional & scientific | 2023 |
| Easthams Wellness Ltd | Arts & recreation | 2026 |
| Eastridge Capital Limited | Professional & scientific | 2011 |
| Eco Licence Ltd | Professional & scientific | 2023 |
| Ecomanta Ltd | Information & communication | 2026 |
| ED REN Investments 2 Africa GP LLP | | 2025 |
| ED REN Investments 2 Africa Holdings GP LLP | | 2025 |
| ED REN Investments 2 Gpco Limited | Professional & scientific | 2025 |
| ED REN Investments 2 SLP GP LLP | | 2025 |
| ED REN Investments 2 UK GP LLP | | 2025 |
| ED REN Investments 2 UK Holdings GP LLP | | 2025 |
| ED REN Investments 2 US GP LLP | | 2025 |
| ED REN Investments 2 US Holdings GP LLP | | 2025 |
| Eddison Developments Limited | Construction | 2018 |
| Eden AB Solar Limited | Energy | 2021 |
| Eden AW Solar Limited | Energy | 2021 |
| Eden BD Solar Limited | Energy | 2021 |
| Eden CF Solar Limited | Energy | 2021 |
| Eden CP Bess Limited | Energy | 2021 |
| Eden FG Solar Limited | Energy | 2019 |
| Eden LD Solar Limited | Energy | 2019 |
| Eden RB Solar Limited | Energy | 2020 |
| Eden Renewables Ltd | Professional & scientific | 2016 |
| Edwina Elkington Jewellery Ltd | Other services | 2020 |
| Egdam Ltd | Agriculture & fishing | 2022 |
| Eglantyne Consultancy Limited | Professional & scientific | 2023 |
| EL Land Restoration Limited | Mining & quarrying | 2024 |
| Elaine's Travel Limited | Administrative & support | 2016 |
| Elcot Letting Ltd | Real estate | 2023 |
| Electra (Swindon) Limited | Construction | 2009 |
| Elements of Avebury Limited | Wholesale & retail | 2016 |