| Rodent Holdings Limited | Financial services | 2019 |
| Roebuck Residential Holdings Limited | Real estate | 2021 |
| Roger M Lambert Limited | Construction | 2003 |
| Rosemary Farm Limited | Agriculture & fishing | 2017 |
| Rowlows Limited | Wholesale & retail | 2012 |
| RPK Enterprises Ltd | Hospitality | 2023 |
| RPM Driving Services Ltd | Transport & logistics | 2011 |
| RPS Lincolnshire Limited | Construction | 2017 |
| RSG Contract Services Ltd | Professional & scientific | 2010 |
| Rubaroc Limited | Manufacturing | 2003 |
| Rugby Motor Company Limited | Wholesale & retail | 2002 |
| Rural Delights Ltd | Wholesale & retail | 2013 |
| Russell Jones Limited | Professional & scientific | 2001 |
| Ryland Design Services Limited | Professional & scientific | 2004 |
| S & J Holdings (Tealby) Limited | Financial services | 2016 |
| S & S Stacey Limited | Information & communication | 2016 |
| S&P Logistics Ltd | Transport & logistics | 2015 |
| S.A.M Advisory (Lincs) Ltd | Wholesale & retail | 2020 |
| S.Drakes Pressure Washing Services Limited | Agriculture & fishing | 2003 |
| S.M.Chatterton Limited | Manufacturing | 2006 |
| Sable Fraser Limited | Hospitality | 2009 |
| Safe Tech Fire Limited | Construction | 2023 |
| Safe-Patch IT Consultancy Limited | Information & communication | 2018 |
| Safiyyah's Spice Ltd | Hospitality | 2023 |
| Samson Products Limited | Wholesale & retail | 2012 |
| Sandhayes Consultancy Limited | Administrative & support | 2025 |
| Sandra Murphy Ltd | Administrative & support | 2024 |
| Sapperton (Lincs) Ltd | Real estate | 2023 |
| Schwampari Soft Drink Co. Limited | Other services | 1990 |
| Sealworks (UK) Limited | Wholesale & retail | 1999 |
| Second Element (Holdings) Limited | Professional & scientific | 2017 |
| Second Element Agriculture Ltd | Agriculture & fishing | 2018 |
| Second Element Compliance Limited | Professional & scientific | 2025 |
| Second Element Group Limited | Professional & scientific | 2025 |
| Second Element Limited | Water & waste | 2002 |
| Second Element Training Limited | Education | 2021 |
| Sefton House Rules Ltd | Real estate | 2016 |
| SELL2MOVE Limited | Wholesale & retail | 2009 |
| Sensor Link Fire & Security Ltd | Administrative & support | 2019 |
| Seven Accounting Limited | Professional & scientific | 2018 |
| SH! Property and Homes Limited | Real estate | 2021 |
| Shelspeed Ltd | Wholesale & retail | 2016 |
| Shepherd Seeds Limited | Agriculture & fishing | 2015 |
| SHG Property Investments Limited | Water & waste | 2026 |
| SHH Love Limited | Information & communication | 2012 |
| Shrewd Management Limited | Professional & scientific | 2011 |
| Sightdrive Limited | Information & communication | 2023 |
| Silt Side Holdings Limited | Professional & scientific | 2013 |
| Silt Side Properties Limited | Construction | 2013 |
| Simbam Investments Limited | Wholesale & retail | 2014 |
| Simon Brace EV Consultancy (Sbevc) Limited | Professional & scientific | 2024 |
| Simon Cheeseman Financial Services Limited | Financial services | 2014 |
| Simon Ives Ltd | Professional & scientific | 2016 |
| Site Competence Ltd | Education | 2021 |
| Site-Survey BC Ltd | Construction | 2019 |
| Sittingbourne Accountancy Services Ltd | Professional & scientific | 1998 |
| Sitto Solutions Ltd | Professional & scientific | 2024 |
| Sixhills Prior Limited | Extraterritorial | 1979 |
| Sixhills Road Management Company Ltd | Households | 2020 |
| SJ Building and Design Limited | Construction | 2019 |
| SJ Wheatley Electrical Limited | Construction | 2005 |
| SKB Event Catering Ltd | Hospitality | 2025 |
| Skedulaa Limited | Information & communication | 2025 |
| Skin Couture Beauty Limited | Other services | 2013 |
| Sky-Eye Security & Hospitality Solutions Ltd | Administrative & support | 2026 |
| Sleaford Day Nursery Limited | Real estate | 2003 |
| Sleaford Properties Limited | Hospitality | 2007 |
| Sleaford Window Company Limited | Construction | 2012 |
| SLW Properties Limited | Real estate | 2016 |
| Smart Drive Motors Limited | Wholesale & retail | 2025 |
| Smart Kitchens and Bedrooms Limited | Wholesale & retail | 2011 |
| Smart Vaping (Harwich) Limited | Wholesale & retail | 2018 |
| Smart Vaping Limited | Wholesale & retail | 2018 |
| Smith & Wesson Limited | Extraterritorial | 2024 |
| Snake Vape Limited | Extraterritorial | 2022 |
| Snipe Properties Limited | Construction | 1987 |
| Socius Accountants Limited | Professional & scientific | 2021 |
| Socius Holdings Limited | Financial services | 2024 |
| Soho Brand Consultancy Limited | Professional & scientific | 2020 |
| Solomon Bay Willmington Ltd | Extraterritorial | 2024 |
| Somersby Homes Limited | Construction | 2019 |
| Soriano Accident Repair Centres Limited | Wholesale & retail | 2025 |
| Soriano Racing Limited | Arts & recreation | 2016 |
| South View Management Company (Fillingham) Ltd. | Extraterritorial | 1992 |
| Southview Consulting Group Ltd | Professional & scientific | 2025 |
| Sparkplugz (Holdings) Limited | Financial services | 2026 |
| Sparksign Ltd | Professional & scientific | 2025 |
| Sparling Agronomy Services Limited | Agriculture & fishing | 2004 |
| SPC 2015 Ltd | Extraterritorial | 2013 |
| Specialist Signs Limited | Extraterritorial | 2022 |
| Speeds (Derby) Limited | Real estate | 2014 |
| Speeds Strawson Ltd | Real estate | 2023 |
| SPG System Services Ltd | Professional & scientific | 2016 |
| Spick & Span Home Services Limited | Administrative & support | 2015 |
| Spridlington Viners Limited | Agriculture & fishing | 1967 |
| Springbok Engineering Limited | Professional & scientific | 1996 |
| Springbok Machinery Limited | Professional & scientific | 1997 |
| Stainfield Farms Limited | Hospitality | 2010 |
| Stan Ploy Limited | Professional & scientific | 2011 |
| Stanley Electronic Services Ltd | Manufacturing | 2013 |