| Eddie Knights Commercials Limited | Wholesale & retail | 2003 |
| Eddison Homes Ltd | Real estate | 2025 |
| Eden (Market Harborough) Limited | Other services | 2020 |
| Eden Bond Ltd | Construction | 2023 |
| Eden Court (Market Harborough) Company Limited | Households | 1985 |
| Edge Bespoke Ltd | Manufacturing | 2019 |
| Edge Carpentry & Joinery Ltd | Construction | 2021 |
| Edgy Productions Limited | Information & communication | 2002 |
| Edmund and Field Ltd | Professional & scientific | 2023 |
| Edridge Film and TV Services Ltd | Information & communication | 2023 |
| EDT Direct ION Limited | Manufacturing | 2001 |
| Edward Connor Solicitors | Professional & scientific | 2017 |
| Edwards Distillers Ltd | Manufacturing | 2023 |
| EEL Consultancy Ltd | Professional & scientific | 2019 |
| Efficiency Control Services Limited | Professional & scientific | 2008 |
| EFW Waring Limited | Manufacturing | 2020 |
| EH Electrical Services Midlands Limited | Construction | 2017 |
| Eidna Limited | Hospitality | 2018 |
| EJF Design & Services Ltd | Professional & scientific | 2026 |
| Ekojoe Community Interest Company | Agriculture & fishing | 2019 |
| Elecross Limited | Wholesale & retail | 2011 |
| Eliona Healthcare Limited | Health & social care | 2013 |
| Elitah Ltd | Professional & scientific | 2018 |
| Elite 6S Leagues Limited | Arts & recreation | 2025 |
| Elite Construction Network Ltd | Professional & scientific | 2025 |
| Elite Private Recruit Limited | Administrative & support | 2025 |
| Elldeli Foods Limited | Hospitality | 2020 |
| Elle Jane Ltd | Hospitality | 2016 |
| Elliecare Ltd | Health & social care | 2023 |
| Elliott Consult Ltd | Professional & scientific | 2011 |
| Ellipse Accountants & Business Advisers Ltd | Extraterritorial | 2017 |
| Elwell Watchorn & Saxton LLP | | 2005 |
| EM Travel Ltd | Administrative & support | 2026 |
| Emac Solutions Ltd | Professional & scientific | 2018 |
| Embody Coaching Ltd | Professional & scientific | 2008 |
| Embrace Sheq Management Services Ltd | Professional & scientific | 2024 |
| Emergent Technology Solutions Limited | Manufacturing | 2015 |
| Emerson and Wests (Holdings) Limited | Financial services | 2023 |
| Emerson and Wests of Market Harborough Limited | Wholesale & retail | 1973 |
| EMG Diesupplies Ltd | Manufacturing | 2017 |
| EMG Tradinguk Limited | Wholesale & retail | 2015 |
| Emkat Solutions Limited | Professional & scientific | 2009 |
| EMM Lettings Ltd | Real estate | 2025 |
| Emma Duchess.Com Limited | Wholesale & retail | 2024 |
| Emmtech Limited | Professional & scientific | 2009 |
| Empire Ground Care Limited | Administrative & support | 2016 |
| Empowered Care Homes Limited | Health & social care | 2024 |
| EMS Properties and Rentals Ltd | Real estate | 2025 |
| Emsak Holdings Limited | Financial services | 2018 |
| END Honour Killings C.I.C. | Health & social care | 2022 |
| Energy Gateway Limited | Education | 2013 |
| Engage & Prosper Ltd | Professional & scientific | 2023 |
| Engine Yard Service Company Ltd | Administrative & support | 2020 |
| Enjoying BPM Ltd | Professional & scientific | 2016 |
| Enrich Tech Solutions Limited | Other services | 2024 |
| Epic Adventure Ltd | Professional & scientific | 2009 |
| Equity Release Council | Other services | 1994 |
| ERC Property and Development Limited | Construction | 2016 |
| Erin Woodger Holdings Ltd | Financial services | 2023 |
| Ermine Street Consultants Limited | Professional & scientific | 2015 |
| Ermine Street Estates Limited | Construction | 2007 |
| ERR Creations Ltd | Manufacturing | 2024 |
| Eshaan Trading Limited | Wholesale & retail | 2015 |
| ESM Applications Ltd | Manufacturing | 2024 |
| Espais Roca Limited | Real estate | 2023 |
| Essential Speech and Language Therapy Ltd | Health & social care | 2020 |
| Essential Stage Supplies Ltd | Extraterritorial | 2007 |
| Establo Coffee Ltd | Manufacturing | 2025 |
| Euromec Contracts Limited | Construction | 1997 |
| European Missionary Fellowship | Other services | 1998 |
| Evenflow Plumbing Ltd | Construction | 2022 |
| Eveson Projects Ltd | Construction | 2015 |
| EVO Utilities Limited | Administrative & support | 2026 |
| Evolution APS Limited | Information & communication | 2024 |
| Evolution Pricing Limited | Professional & scientific | 2016 |
| Evolve by Katie Ltd | Administrative & support | 2025 |
| Evolve Coaching Ltd | Other services | 2019 |
| Evolve Martial Arts CIC | Education | 2026 |
| Evolve to Grow Ltd | Professional & scientific | 2009 |
| EWF Consulting Ltd | Professional & scientific | 2021 |
| EWF Fit Kettering Ltd | Arts & recreation | 2021 |
| EWF Fit Market Harborough Ltd | Arts & recreation | 2021 |
| EWF Group Ltd | Arts & recreation | 2020 |
| Exceed NRG UK Limited | Construction | 2023 |
| Exceptional Trailer Sales Limited | Wholesale & retail | 2015 |
| Executive Talent Limited | Administrative & support | 2007 |
| Exine Technology Limited | Information & communication | 2018 |
| Eyebrook Feeds Limited | Extraterritorial | 2002 |
| EZ Technology Limited | Wholesale & retail | 2016 |
| Ezee Group International Limited | Manufacturing | 2015 |
| F&J Distribution Ltd | Wholesale & retail | 2026 |
| F9 Construction Limited | Construction | 2026 |
| FAB Trading Limited | Wholesale & retail | 2016 |
| Fabricorp.Net Limited | Professional & scientific | 2010 |
| Fabulous Accountancy Limited | Professional & scientific | 2017 |
| Fabulous Advisory Limited | Professional & scientific | 2020 |
| Fabulous Financial Limited | Professional & scientific | 2020 |
| Fabulous Group Limited | Professional & scientific | 2020 |
| Fabulous Marketing Limited | Professional & scientific | 2020 |
| Fabulous People Limited | Administrative & support | 2021 |