| Scripdrop Limited | Wholesale & retail | 2026 |
| SCT Projects Limited | Manufacturing | 2022 |
| SCW Design and Fit Ltd | Construction | 2025 |
| Seamless Construction Limited | Construction | 2013 |
| Seandavis Transport Limited | Transport & logistics | 2013 |
| Second Chance Classics Limited | Wholesale & retail | 2023 |
| Send Support Services Ltd | Education | 2025 |
| SFE Family Houses Limited | Real estate | 2022 |
| Sharpening Centre Ltd | Professional & scientific | 2024 |
| Shaun Carter Racing Limited | Professional & scientific | 2023 |
| Shebdon Farm Barns Management Company Limited | Extraterritorial | 2010 |
| Shed Eventing Ltd. | Hospitality | 2023 |
| Sheldon Bourne Services Limited | Professional & scientific | 2021 |
| Shepherd Inns Ltd | Real estate | 2005 |
| Shepley's Butchers Limited | Wholesale & retail | 2015 |
| Show Motions Limited | Administrative & support | 2018 |
| Shropshire 1797 Investments Limited | Real estate | 2020 |
| Shropshire Alloy Fabrications Limited | Manufacturing | 2018 |
| Shropshire Barber Limited | Other services | 2019 |
| Shropshire Car Sales Ltd | Wholesale & retail | 2022 |
| Shropshire Commercial Trading Limited | Real estate | 2011 |
| Shropshire Day Care Centre Limited | Health & social care | 2022 |
| Shropshire Heat Limited | Financial services | 2010 |
| Shropshire Joinery and Construction Ltd | Construction | 2023 |
| Shropshire Off-Grid Heating Ltd | Construction | 2024 |
| Shropshire OIL and GAS Ltd | Construction | 2016 |
| Shropshire PIT Bikes Ltd | Wholesale & retail | 2024 |
| Shropshire Respite Centre Limited | Health & social care | 2022 |
| Shropshire Roofing & General Building Ltd | Construction | 2020 |
| Signfish Ltd | Professional & scientific | 2022 |
| Silver Close (Norton) Limited | Households | 2020 |
| Silver Spur Livery Ltd | Agriculture & fishing | 2019 |
| Simon Sherwin Limited | Wholesale & retail | 2009 |
| Simplysim Solutions Ltd | Wholesale & retail | 2025 |
| SJ Clifford Investments Limited | Real estate | 2024 |
| Sjcrecruitment Ltd | Administrative & support | 2024 |
| SK Poultry Services Limited | Agriculture & fishing | 2016 |
| SKE Partnership Limited | Real estate | 2014 |
| Skitt Consulting Ltd | Information & communication | 2021 |
| Skrd Limited | Professional & scientific | 2014 |
| Sky RAY Ltd | Wholesale & retail | 2025 |
| Sky Wing Express Courier Ltd | Transport & logistics | 2025 |
| Skyreach Solutions Ltd | Administrative & support | 2025 |
| Slater Farms Limited | Agriculture & fishing | 2013 |
| SLE Property Limited | Real estate | 2021 |
| Sloanmarsh Ltd | Hospitality | 2025 |
| SM Chatha Limited | Real estate | 2025 |
| Smalltech Ltd | Information & communication | 2006 |
| Smithfield Motors Ltd | Wholesale & retail | 2019 |
| Smithy Maintenance Limited | Administrative & support | 2011 |
| SMJ Autoservice Ltd | Wholesale & retail | 2018 |
| SMR Recycling Limited | Water & waste | 2014 |
| Soffi Parker Ltd | Wholesale & retail | 2021 |
| Solen Stewardship Limited | Agriculture & fishing | 2025 |
| Solen Web Development Ltd | Information & communication | 2020 |
| Some Nice Productions Limited | Professional & scientific | 2023 |
| Southeastern Trading Corporation Ltd | Construction | 2020 |
| Southern Comfort Cattery Ltd | Other services | 2026 |
| SP Caravan & Motorhome Servicing Ltd | Wholesale & retail | 2025 |
| SP Holiday Lets Limited | Real estate | 2021 |
| Specialised Pest Services Limited | Administrative & support | 2026 |
| Specialist Farm Enterprises Limited | Agriculture & fishing | 2010 |
| Spikey Enterprise Limited | Wholesale & retail | 2024 |
| Sports ER (International) Limited | Professional & scientific | 2018 |
| Sports ER Limited | Health & social care | 2009 |
| Springfield Golf Ltd | Arts & recreation | 2024 |
| Squirrel Asset Management Ltd | Real estate | 2019 |
| SRF Consulting Ltd | Professional & scientific | 2022 |
| Staffbreaks Ltd | Wholesale & retail | 2026 |
| Staffordshire Bathrooms Limited | Construction | 2016 |
| Staffordshire Fire Doors Limited | Wholesale & retail | 1939 |
| Stage Tech Event Hire Limited | Administrative & support | 2023 |
| Stamer House (Penkhull) Management Limited | Hospitality | 2005 |
| Stephensons Properties Group Limited | Real estate | 2024 |
| Steve Walwyn Financial Planning Ltd | Financial services | 2012 |
| Stevens Collision Repair Specialists Ltd | Wholesale & retail | 2013 |
| Stevens Hospitality Group Ltd | Hospitality | 2020 |
| Stobus Business Consultancy Ltd | Administrative & support | 2020 |
| Stripes & Graphics Ltd | Professional & scientific | 2020 |
| Stubbs Builders (Norbury) Limited | Construction | 2003 |
| Studley Farm Limited | Construction | 2018 |
| Styche Hall Management Company Limited | Hospitality | 1987 |
| Styche Valley Services Limited | Agriculture & fishing | 2010 |
| Sugnall Farms Limited | Agriculture & fishing | 2000 |
| Sumit Systems Ltd | Administrative & support | 1999 |
| Summerfield Surveyors Limited | Real estate | 2019 |
| Supa Strikers North Shropshire Ltd | Arts & recreation | 2023 |
| Supermarket Surplus Limited | Wholesale & retail | 2011 |
| Superviseme Ltd | Information & communication | 2020 |
| Supply Chain Integrators Limited | Professional & scientific | 2011 |
| Surplus Papers Limited | Wholesale & retail | 2010 |
| Surrey Fire and Security Systems Ltd | Construction | 2021 |
| Sutton Lakes Limited | Real estate | 2009 |
| Swanley Developments Ltd | Professional & scientific | 1997 |
| Swanpit Nurseries Limited | Wholesale & retail | 2002 |
| SWF Roofers & Builders Ltd | Construction | 2022 |
| Swin Autos Limited | Wholesale & retail | 2023 |
| T B Builders Limited | Construction | 2002 |
| T.W. Dixon (Developments) Limited | Construction | 2014 |
| TAG Lane Holdings Ltd | Financial services | 2023 |