| Dcsl Limited | Health & social care | 2008 |
| Debt Collection Law Firm Ltd | Financial services | 2010 |
| Decalux Consulting Ltd | Information & communication | 2022 |
| Decebal Consulting Ltd | Construction | 2025 |
| Decodel Ltd | Transport & logistics | 2016 |
| Defaultcollective Ltd | Information & communication | 2012 |
| Delfland Nurseries Limited | Agriculture & fishing | 1985 |
| Deller Moore Ltd | Professional & scientific | 2019 |
| Devis Convenience Store Limited | Wholesale & retail | 2021 |
| DH Aero Ltd | Manufacturing | 2023 |
| Diamond Flooring & Carpets Ltd | Wholesale & retail | 2025 |
| Digital Accounting Services Ltd | Extraterritorial | 2025 |
| Digital Evolution Matrix Ltd | Extraterritorial | 2025 |
| Dilson Leeding Ltd | Real estate | 2018 |
| Dilson Leeding Peterborough Ltd | Financial services | 2018 |
| Dimitro Annis Ltd | Wholesale & retail | 2019 |
| Direct Vehicle Locks Ltd | Wholesale & retail | 2023 |
| DJW Infastructure UK Limited | Construction | 2024 |
| DM Utilities Limited | Construction | 2010 |
| Doctor Tree Ltd | Administrative & support | 2017 |
| Doddington the 100TH Club CIC | Other services | 2024 |
| Dodoiu Limited | Professional & scientific | 2021 |
| Dodson Bros. (Thatchers) Limited | Construction | 1978 |
| Doggy Styling Limited | Other services | 2019 |
| Dollar Label Ltd | Wholesale & retail | 2024 |
| Donna Elvira (UK) Ltd | Wholesale & retail | 2020 |
| Doorbrite Ltd | Other services | 2022 |
| Dottie About Ltd | Wholesale & retail | 2024 |
| Doublespark Limited | Information & communication | 2005 |
| Dougill Food Engineering Ltd | Professional & scientific | 2017 |
| Dovydas Trans Ltd | Transport & logistics | 2018 |
| DPR Surveys Ltd | Professional & scientific | 2021 |
| Drainage & Roofing Central Limited | Wholesale & retail | 2021 |
| Drum Ventures Ltd | Wholesale & retail | 2020 |
| DSO Network Ltd | Professional & scientific | 2024 |
| DSP Electrical Ltd | Construction | 2020 |
| Dual Climate Air Conditioning Ltd | Construction | 2025 |
| Dunham Management Ltd | Administrative & support | 2018 |
| Dykemoor Farm Ltd | Agriculture & fishing | 2002 |
| Dylcor Limited | Information & communication | 2018 |
| Dynamic FAN Services Ltd | Professional & scientific | 2023 |
| E R Fisher Ltd | Health & social care | 2022 |
| E.H.Morris(Stonea)Limited | Agriculture & fishing | 1963 |
| East Anglia Utilities Ltd | Energy | 2017 |
| Easy Cooling Company Ltd | Construction | 2009 |
| Eco Hand Car Wash Ltd | Other services | 2023 |
| Edward Ventures Limited | Wholesale & retail | 2021 |
| Edwards Bros. (Spaldwick) Limited | Agriculture & fishing | 1958 |
| Edycare Ltd | Health & social care | 2023 |
| EGB Real Estate Ltd | Financial services | 2025 |
| EGB Vacuum Limited | Manufacturing | 2005 |
| EGE Services Ltd | Construction | 2021 |
| EGF Installations Ltd | Construction | 2013 |
| Egnal Limited | Transport & logistics | 2004 |
| Elecomp Co. Ltd | Wholesale & retail | 2006 |
| Electrical Ventures Limited | Construction | 2021 |
| Elite Building and Groundworks Ltd | Construction | 2020 |
| Elite Packing Services Limited | Administrative & support | 2011 |
| Elite Surfacing & Civils Ltd | Construction | 2023 |
| Elkin Plumbing & Heating Ltd | Construction | 2025 |
| Elliptical Design Limited | Administrative & support | 2011 |
| Elmhurst Electrical Ltd | Construction | 2024 |
| Elon Electrical Ltd | Construction | 2024 |
| Elysian Medical Aesthetics Clinic Ltd | Health & social care | 2025 |
| EMI Interiors Ltd | Construction | 2015 |
| Enis Construction Solutions Ltd | Construction | 2016 |
| Ensign Motors Limited | Wholesale & retail | 2010 |
| Environmental Science Hygiene Limited | Manufacturing | 2020 |
| EO Contractors Limited | Construction | 2022 |
| EP Fast Food Ltd | Hospitality | 2023 |
| Essential Salon Supplies Ltd | Wholesale & retail | 2020 |
| Estafest CIC | Arts & recreation | 2024 |
| Estover Properties Limited | Construction | 2019 |
| EU Kabel Ltd | Manufacturing | 2016 |
| Eurogreen Limited | Water & waste | 2025 |
| Europa Express Service Limited | Wholesale & retail | 2017 |
| Eventus Hire (Lincoln) Ltd | Administrative & support | 2024 |
| Ezgin Ltd | Real estate | 2023 |
| F.C.S. Construction Limited | Other services | 1999 |
| F.J.S. Services Limited | Manufacturing | 2006 |
| Fairfax Ventures Holdings Limited | Financial services | 2020 |
| Fairfax Ventures Limited | Financial services | 2020 |
| Farlow Technical Services Limited | Professional & scientific | 2015 |
| FDI Construction Ltd | Construction | 2019 |
| Fengari Empire Ltd | Professional & scientific | 2021 |
| Fengimushrooms Ltd | Agriculture & fishing | 2026 |
| Fenland Area Community Enterprise Trust | Education | 2002 |
| Fenland Auction Services Limited | Wholesale & retail | 2014 |
| Fenland Business Services Ltd | Professional & scientific | 2005 |
| Fenland Car Breakers Ltd | Wholesale & retail | 2019 |
| Fenland Cooling Services Limited | Construction | 2023 |
| Fenland Eco Builders (Soham) Limited | Extraterritorial | 2010 |
| Fenland Future Limited | Construction | 2020 |
| Fenland Heating Services Limited | Construction | 2019 |
| Fenland Liftrucs Limited | Manufacturing | 2007 |
| Fenland Mega Storage Ltd | Transport & logistics | 2023 |
| Fenland Metalica Ltd | Manufacturing | 2016 |
| Fenland PCN Ltd | Health & social care | 2024 |
| Fenland Poultry & Game Ltd | Agriculture & fishing | 2021 |
| Fenland Property Developers Limited | Real estate | 2010 |