| UK Pubs & Bars Ltd | Hospitality | 2023 |
| UK Vehicle Inspection Limited | Extraterritorial | 2011 |
| UKB Developments Limited | Construction | 2022 |
| Ukpubs Limited | Hospitality | 2020 |
| Ukvi Limited | Extraterritorial | 2011 |
| UL Wire and Cable Ltd | Wholesale & retail | 2021 |
| Ultimate Nails & Beauty Limited | Other services | 2003 |
| Ulvex Ltd | Administrative & support | 2026 |
| Ulwc Holdings Ltd | Financial services | 2025 |
| Ulyth Healthcare Consultancy Ltd | Health & social care | 2021 |
| Ummah Supermarket Ltd | Wholesale & retail | 2025 |
| UNA Alliance Limited | Financial services | 2009 |
| Unimark Limited | Wholesale & retail | 2026 |
| Union Public House Limited | Hospitality | 2006 |
| Uniplas UK Limited | Manufacturing | 2004 |
| Unique Home Living Limited | Real estate | 2025 |
| Unique Kitchens, Bedrooms & Bathrooms Limited | Manufacturing | 2014 |
| Unique Properties (Midlands) Ltd | Real estate | 2024 |
| Unitas Alliance Limited | Extraterritorial | 2014 |
| Unite Lettings Nottingham Ltd | Real estate | 2025 |
| United Kingdom Property Services Limited | Real estate | 2019 |
| United Kingdom Without Incineration Network (Ukwin) | Other services | 2008 |
| United Training Solutions Ltd | Education | 2020 |
| Unity ST Commercials Ltd | Real estate | 2026 |
| Universal Caring Services Ltd | Health & social care | 2016 |
| Universal Civils and Build Ltd | Construction | 2019 |
| Universal Colourworks Limited | Wholesale & retail | 2014 |
| Universal Event Catering Ltd | Hospitality | 2024 |
| Universal Fabrications Limited | Construction | 2025 |
| Universal Property Rentals Limited | Construction | 2016 |
| Universal Resource Solutions Ltd | Administrative & support | 2019 |
| University Associates International Limited | Real estate | 1974 |
| Unlim 600 Ltd | Wholesale & retail | 2016 |
| Unreal Technologies Limited | Information & communication | 2020 |
| Untitled Multimedia Ltd | Wholesale & retail | 2025 |
| UP and Down Plastics Ltd | Wholesale & retail | 2024 |
| UP Systems Limited | Manufacturing | 2000 |
| Upiluwan Software Development and Logistics Limited | Information & communication | 2015 |
| Upper Room Prayer Ministries Limited | Other services | 2020 |
| Upslant Ltd | Professional & scientific | 2025 |
| Urban Activities Ltd | Arts & recreation | 2024 |
| Urban Exotics (Mansfield) Limited | Wholesale & retail | 2015 |
| Urban Five Ltd | Wholesale & retail | 2025 |
| Urban Fusion Developments Limited | Construction | 2021 |
| Urban Joinery Ltd | Construction | 2021 |
| Urban Mycology Ltd | Wholesale & retail | 2024 |
| Urban Properties Investments Ltd | Real estate | 2017 |
| URS Resources Ltd | Administrative & support | 2022 |
| USC IP Limited | Extraterritorial | 2009 |
| Ustor Limited | Administrative & support | 2003 |
| Utility Select Limited | Manufacturing | 2020 |
| V200 Wealth Management Ltd | Financial services | 2018 |
| VAB Property Ltd | Real estate | 2025 |
| Vabk Ltd | Professional & scientific | 2021 |
| Vaco Libertas Holdings Limited | Financial services | 2024 |
| Vahterus (UK) Limited | Administrative & support | 1999 |
| Vaid Assets Limited | Real estate | 2022 |
| Vaid Capital Investments Ltd | Real estate | 2021 |
| Vale & Brown Properties Limited | Real estate | 2024 |
| Vale Holdings Limited | Financial services | 2007 |
| Vale House Limited | Households | 2011 |
| Vale Property Company (Midland and Regional) Limited | Real estate | 2016 |
| Vale Window Company Limited | Manufacturing | 1996 |
| Vale Windows Stockport Limited | Professional & scientific | 2007 |
| Valence Projects Ltd | Real estate | 2025 |
| Valencia Estates Limited | Real estate | 2018 |
| Valencia Properties Limited | Real estate | 2018 |
| Valkyrie Construction Limited | Construction | 2018 |
| Valloor UK Ltd | Wholesale & retail | 2024 |
| Vanga Properties Ltd | Real estate | 2026 |
| Vanguard Securities Ltd | Financial services | 2025 |
| Vanilla Property Ltd | Real estate | 2020 |
| Vape HQ (Lincoln) Limited | Wholesale & retail | 2009 |
| Vape HQ Holdings Limited | Financial services | 2026 |
| Vape HQ Retail Limited | Wholesale & retail | 2015 |
| Vape HQ Stocksbridge Limited | Wholesale & retail | 2015 |
| Vape HQ Stores Limited | Wholesale & retail | 2015 |
| Vapehq Limited | Wholesale & retail | 2012 |
| Vapex Eastwood Limited | Other services | 2019 |
| Varee Limited | Arts & recreation | 2012 |
| Variety Island Ltd | Hospitality | 2023 |
| Vartico Ltd | Administrative & support | 2017 |
| Vaughandale Construction Limited | Construction | 1991 |
| Vaughandale Holdings Limited | Financial services | 2011 |
| Vault Contracts Limited | Administrative & support | 2017 |
| Vault Electronic Security Limited | Administrative & support | 2007 |
| Vault Group HQ Ltd | Extraterritorial | 2019 |
| Vault Security Limited | Extraterritorial | 2018 |
| Vaults Financial Services Limited | Professional & scientific | 2013 |
| Vaultwolf Ltd | Financial services | 2025 |
| Vayun Systems Limited | Professional & scientific | 2026 |
| VCL Associates Limited | Administrative & support | 2013 |
| Vector Heroes Ltd | Wholesale & retail | 2021 |
| Vehicle Car Products Limited | Wholesale & retail | 2024 |
| Velop Developments Ltd | Construction | 2020 |
| Velop Lettings Limited | Real estate | 2020 |
| Velopair Apartments Ltd | Hospitality | 2018 |
| Velor Plumbing and Maintenance Ltd | Construction | 2026 |
| VEN Construction Limited | Construction | 2020 |
| Vencat Ventures Ltd | Real estate | 2022 |