| Domelab Ltd | Wholesale & retail | 2026 |
| Domenn Properties (Two) Limited | Real estate | 2016 |
| Domenn Properties Limited | Real estate | 2005 |
| Domepride Limited | Health & social care | 1983 |
| Domestic and Commercial Northwest Ltd | Administrative & support | 2025 |
| Domestic Appliances Online Limited | Households | 2016 |
| Domestic Builders Ltd | Construction | 2023 |
| Domestic Conversions Limited | | 1971 |
| Domestic Electricals Ltd | Construction | 2017 |
| Domestic Optimise Ltd | Administrative & support | 2026 |
| Domestic-Air Ltd | Manufacturing | 2019 |
| Domesticcleans Ltd | Administrative & support | 2025 |
| Domesticode Technologies Ltd | Information & communication | 2025 |
| Domfem International Ltd | Transport & logistics | 2019 |
| Dominant Cleaning Service Ltd | Administrative & support | 2025 |
| Dominant in Health Care Solution Ltd | Health & social care | 2014 |
| Dominex Stratixy Solutions Ltd | Extraterritorial | 2026 |
| Dominic & Co Consultancy Ltd | Professional & scientific | 2009 |
| Dominic Jerome Ltd | Real estate | 2020 |
| Dominic Keavey Limited | Information & communication | 2003 |
| Dominic Margiotta Limited | Extraterritorial | 2024 |
| Dominic Spray Anaesthesia Ltd | Health & social care | 2012 |
| Dominick House Development Ltd | Real estate | 2025 |
| Dominion City Manchester | Education | 2022 |
| Dominion Colony 7102 Limited | Administrative & support | 2019 |
| Dominion Debt Recovery Limited | Administrative & support | 2024 |
| Dominion Support 24/7 Limited | Public administration | 2026 |
| Domino Recruitment Ltd | Administrative & support | 2017 |
| Dominus Fortress Ltd | Administrative & support | 2024 |
| Domis CW (LUV) Limited | Financial services | 2024 |
| Domizil 2 Ltd | Extraterritorial | 2023 |
| Domizil 4 Ltd | Extraterritorial | 2023 |
| Domizil 5 Ltd | Extraterritorial | 2023 |
| Domo Property Ltd | Real estate | 2025 |
| Domoore Park Limited | Professional & scientific | 2022 |
| Domorade Limited | Real estate | 2001 |
| Domovly Ltd | Construction | 2022 |
| Doms 360 Constructions Ltd | Administrative & support | 2022 |
| Domus BWW UK Holdings Limited | Financial services | 2013 |
| Domus Estates Associates Limited | Real estate | 2024 |
| Domus Felicitas Holdings Limited | Wholesale & retail | 2025 |
| Domus Health Care Limited | Health & social care | 2023 |
| Domus Invest Ltd | Real estate | 2013 |
| Domus Joinery & Build Ltd | Construction | 2024 |
| Domville Builders Limited | Construction | 2015 |
| DON Darcy Ltd | Wholesale & retail | 2023 |
| DON Dent Limited | Health & social care | 2026 |
| DON Giovanni's (Knutsford) Limited | Hospitality | 2016 |
| DON Isaac Ltd | Wholesale & retail | 2019 |
| DON Kastro Ltd | Hospitality | 2026 |
| DON Luigi EST. 1988 Ltd | Hospitality | 2024 |
| Don'T Blink Productions Ltd | Information & communication | 2025 |
| Don'T Forget Enterprises Limited | Professional & scientific | 2014 |
| Don-Sergio Services Ltd | Professional & scientific | 2021 |
| Donald Developments (NO.2) Ltd | Other services | 2017 |
| Donald Wardle and SON Limited | Wholesale & retail | 1994 |
| Donate My Cashback Ltd | Information & communication | 2024 |
| Donatella Limited | Extraterritorial | 2022 |
| Doncaster Sheffield Airport Limited | Transport & logistics | 1999 |
| Doncasters Chard Limited | Manufacturing | 1964 |
| Doncastle Ltd | Real estate | 2023 |
| Donda Music Limited | Information & communication | 2020 |
| Dondada Enterprises Ltd | Wholesale & retail | 2020 |
| Done Differently Ltd | Information & communication | 2025 |
| Donegall Assets (NO 2) Limited | Extraterritorial | 2012 |
| Donegall Holdco Limited | Extraterritorial | 2014 |
| Donelan Property Investments Ltd | Financial services | 2018 |
| Donelan Property Limited | Real estate | 2016 |
| Donelan Property Maintenance Limited | Real estate | 2022 |
| Doneli Ltd | Manufacturing | 2025 |
| Doner HUT Limited | Other services | 2023 |
| Dong Guan Manchester Limited | Hospitality | 2014 |
| Dongchen International Enterprise Co., Ltd | Administrative & support | 2016 |
| Donggua BR Ltd | Wholesale & retail | 2026 |
| Dongying Catering Limited | Hospitality | 2024 |
| Donjon Creations Ltd | Wholesale & retail | 2019 |
| Donka Professional Ltd | Professional & scientific | 2022 |
| Donmarco Ltd | Hospitality | 2015 |
| Donn Design Limited | Professional & scientific | 2003 |
| Donn Investments Limited | Real estate | 1964 |
| Donna Imports (UK) Ltd | Wholesale & retail | 2019 |
| Donna Sofia Ltd | Hospitality | 2019 |
| Donnatella Domestic Services Limited | Administrative & support | 2021 |
| Donne House Limited | Wholesale & retail | 2022 |
| Donnellan Properties Ltd | Real estate | 2025 |
| Donnells Jewellers Limited | Wholesale & retail | 2012 |
| Donnison & Smith Engineering Limited | | 1983 |
| Dons Kick Spot Ltd | Wholesale & retail | 2025 |
| Dont Forget Your Hairbrush Ltd | Wholesale & retail | 2025 |
| Dontelea Limited | Wholesale & retail | 2026 |
| Dontleanonthat Ltd | Real estate | 2026 |
| Dontrelle Medical Ltd | Health & social care | 2015 |
| DOO Read Ltd | Information & communication | 2025 |
| Dooc Consults Ltd | Health & social care | 2015 |
| Dooc Properties Limited | Real estate | 2022 |
| Doodledo Limited | Information & communication | 2007 |
| Doodledo Property Ltd | Real estate | 2020 |
| Doodles Driving Services Ltd | Education | 2024 |
| Doofast Limited | Construction | 1973 |
| Doofox Ltd | Information & communication | 2026 |