| Dogtooth Limited | Arts & recreation | 2006 |
| Dogtooth Property Ltd | Real estate | 2017 |
| DOT Build Ltd | Construction | 2020 |
| Dots Project Delivery Ltd | Professional & scientific | 2014 |
| Doyler Limited | Arts & recreation | 2012 |
| DP Plumbing & Bathrooms Ltd | Construction | 2021 |
| Driffix Ltd | Construction | 2020 |
| Dukes Group Ltd | Hospitality | 2014 |
| E & R Assets Ltd | Real estate | 2016 |
| E Andrew Hughes Ltd | Agriculture & fishing | 2015 |
| E Coast Trading Ltd | Wholesale & retail | 2023 |
| EA Sales & Management Limited | Wholesale & retail | 2023 |
| East Yorkshire Clay Shooting Ground Ltd | Arts & recreation | 2018 |
| Eazy Office Supplies Ltd | Wholesale & retail | 2021 |
| EIA Ventures Ltd | Real estate | 2025 |
| Electrical Systems Integrator Ltd | Professional & scientific | 2023 |
| Element UK Holdco Limited | Financial services | 2017 |
| Element UK Midco Limited | Financial services | 2017 |
| Element UK Topco Limited | Financial services | 2017 |
| Elevate OUR Everyday Ltd | Professional & scientific | 2024 |
| Elia's Corner Ltd | Hospitality | 2025 |
| Elite Creator Network Ltd | Professional & scientific | 2024 |
| Elite Fencing and Ground Works Ltd | Administrative & support | 2025 |
| Elite Veterinary Ltd | Professional & scientific | 2023 |
| Elizabeth Bentley Limited | Health & social care | 2013 |
| Ellie MAI Interiors Ltd | Manufacturing | 2024 |
| Elliott and Houlder Limited | Construction | 2017 |
| Ellis Patents Holdings Limited | Manufacturing | 2012 |
| Ellis Patents Limited | Manufacturing | 1977 |
| Ellmpark Ltd | Professional & scientific | 2019 |
| Embedded Edge Ltd | Professional & scientific | 2023 |
| Embleton Technical Services Limited | Professional & scientific | 2024 |
| Embtek Limited | Information & communication | 2013 |
| EMC Technology Ltd | Wholesale & retail | 2026 |
| Emily Sutton Limited | Arts & recreation | 2017 |
| Empire Group North Yorkshire Ltd | Administrative & support | 2019 |
| EMS Electrical Ltd | Construction | 2021 |
| Encephalitis International | Professional & scientific | 2001 |
| Energy Process Partners Ltd | Professional & scientific | 2026 |
| Engineering and Marine Services Limited | Professional & scientific | 2012 |
| Enigma Lakes Ltd | Agriculture & fishing | 2024 |
| Enstor (Harrogate) Limited | Real estate | 2017 |
| Enstor (Malton) Limited | Other services | 2016 |
| Enterprise Cube C.I.C. | Administrative & support | 2012 |
| Environmental Art Ltd | Manufacturing | 2018 |
| Environmental Smart CIC | Professional & scientific | 2025 |
| Eprod Software UK Ltd. | Information & communication | 2021 |
| Equine Reproductive Services (UK) Limited | Professional & scientific | 2012 |
| Equiprofile Ltd | Professional & scientific | 2017 |
| Ernest Gray Properties Limited | Real estate | 2019 |
| Eskholme Property (Whitby) Ltd | Households | 2024 |
| Esmari Homes Ltd | Real estate | 2023 |
| Evans & James Associates Ltd | Professional & scientific | 2015 |
| Everest Telecoms Ltd | Professional & scientific | 2022 |
| Every Season Group Ltd | Information & communication | 2022 |
| Everyone Building Needs Ltd | Construction | 2024 |
| Extramuros Ltd. | Professional & scientific | 2015 |
| F P Marine Protection Ltd | Manufacturing | 2026 |
| Falcon Facilities Management Ltd | Administrative & support | 2019 |
| Fallowfield Group Limited | Financial services | 2026 |
| Fantastic Pubs Limited | Hospitality | 2025 |
| Farekna Limited | Wholesale & retail | 2013 |
| Farming Renewable Energy Limited | Wholesale & retail | 2021 |
| Fashion Reborn by Shona Ltd | Wholesale & retail | 2026 |
| Fellstone Projects Ltd | Professional & scientific | 2022 |
| Feng's SPV Ltd. | Hospitality | 2021 |
| Fergus Court Funeral Services Limited | Other services | 2016 |
| Fernhill Developments Limited | Construction | 2002 |
| Fine Wine Works Limited | Wholesale & retail | 2012 |
| Fisher Brothers Limited | Hospitality | 2016 |
| Flamingo Land Resort Limited | Arts & recreation | 2009 |
| Fletchers Coaches Ltd | Transport & logistics | 2023 |
| Flint Hall Bloodstock Ltd | Arts & recreation | 2019 |
| Flintoft Ironmongers Limited | Wholesale & retail | 2015 |
| Flinton Property Investment Ltd | Real estate | 2025 |
| Florios (Ryedale) Ltd | Hospitality | 2018 |
| Floris Cleaning Ltd | Administrative & support | 2020 |
| Flowergate Properties Ltd | Professional & scientific | 2014 |
| Flowstate Property Ltd | Real estate | 2021 |
| Flymenow Limited | Transport & logistics | 2005 |
| Flyprivately Limited | Extraterritorial | 2016 |
| Fmcg Project Solutions Ltd | Professional & scientific | 2019 |
| Food Orbit Ltd | Professional & scientific | 2018 |
| Football Life Events Limited | Information & communication | 2014 |
| Football Life Management Limited | Information & communication | 2014 |
| Football Life Production Limited | Information & communication | 2014 |
| Football Life Publications Ltd | Information & communication | 2013 |
| Forever Bouquets Ltd | Wholesale & retail | 2017 |
| Forman Management Services Limited | Administrative & support | 2019 |
| Fortifide Properties Ltd | Real estate | 2025 |
| Fortysix Events Ltd | Hospitality | 2026 |
| Four Storey Ltd | Real estate | 2010 |
| Foxy's 4 Paws Ltd | Wholesale & retail | 2019 |
| Freddy & Bobby Ltd | Other services | 2022 |
| Freedom and FUN Limited | Other services | 2022 |
| French Trading Limited | Extraterritorial | 2024 |
| From the Heart Waxmelts Ltd | Manufacturing | 2020 |
| FSP Services Ltd | Hospitality | 2024 |
| FTR Services Ltd | Professional & scientific | 2025 |
| Fundamentals 24/7 Limited | Other services | 2024 |